CAS: 1118-84-9; Allyl Acetoacetate

相似化合物

141-97-9 22418-80-0 77504-73-5

上下游产品

CAS号105-45-3 乙酰乙酸甲酯 | CAS号107-18-6 烯丙醇 | CAS号141-97-9 乙酰乙酸乙酯 | CAS号674-82-8 双乙烯酮 | CAS号88593-98-0 3-bromopropyl 3... | CAS号1694-31-1 乙酰乙酸叔丁酯 | CAS号321904-66-9 prop-2-enyl 6-e... | CAS号85920-63-4 5-(1-羟基亚乙基)-2,2... | CAS号107-05-1 氯丙烯 | CAS号111903-66-3 prop-2-enyl 2-m... | CAS号5396-89-4 乙酰丙酮苄酯 | CAS号21045-82-9 prop-2-enyl 2-c... | CAS号206446-98-2 4-hydroxy-5-phe... | CAS号132008-24-3 prop-2-enyl 3-p... | CAS号3508-78-9 3-烯丙基戊烷-2,4-二酮 | CAS号109-49-9 烯丙基丙酮 | CAS号75265-80-4 3-prop-2-enylhe... | CAS号67-64-1 丙酮 | CAS号58547-18-5 4-hydroxy-6-phe...

Prop-2-Enyl 6-Ethoxy-5,6-Dihydro-2-Methyl-1,4-Oxathiin-3-Carboxylate置于间氯过氧苯甲酸体系中,用 二氯甲烷,氯仿 用作溶剂,化学反应 300.0H,反应生成乙酰乙酸烯丙酯
参考文献:α,α'-二氧代亚砜的分子内杂diels-Alder反应-[3.3.1]-双环骨架的新途径
标题:α,α'-二氧代亚砜的分子内杂diels-Alder反应-[3.3.1]-双环骨架的新途径
摘要:叔丁基硫基取代的1,4-氧杂草黄素的简单转化允许制备草硫黄素s-氧化物.这些反过来是相应的具有束缚的内部富电子双键的α,α'-二氧亚砜二烯的合适的前体.检查这些亚砜的合成效用,我们观测到水解或分子内环加成反应,取决于反应中心之间的距离和双键上的取代.从环加成物中获得具有[3.3.1]骨架和sp 2桥头碳的双环衍生物.
Doi:10.1002/1099-0690(200011)2000:22<3721::Aid-Ejoc3721>3.0.Co;2-B

专利信息

专利号:WO-2013164856-A1
优先权日:2012-05-04
标题 :A process for preparing intermediates of 10-propargyl-10-deazaaminopterin (pralatrexate) synthesis and the intermediates thereof
发明人：ALLA RAMA RAO VENKATA; RAMARAO CHANDRASHEKAR; MICHEL PATRICK THOMAS; NITLIKAR LAKSHMIKANT HANUMANTHRAO; KALAM BHUPATHI REDDY; DUDUKA RAMPRASAD
权利人:AVRA LAB PRIVATE LTD; ALLA RAMA RAO VENKATA; RAMARAO CHANDRASHEKAR; MICHEL PATRICK THOMAS; NITLIKAR LAKSHMIKANT HANUMANTHRAO; KALAM BHUPATHI REDDY; DUDUKA RAMPRASAD
摘要:A process for preparation of 4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic acid and other key intermediates in synthesis of 10-propargyl-10-deazaaminopterin (Pralatrexate) and the intermediates thereof. The 10-propargyl-10-deazaaminopterin (Pralatrexate) is obtained by peptide formation and ester hydrolysis of the intermediate compound 4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic acid by methods known in the art.

专利号:US-10799441-B2
优先权日:2011-06-06
标题:Skin treatments containing pyrroloquinoline quinone (PQQ) esters and methods of preparation and use thereof
发明人：LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C
权利人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C; PCR TECH HOLDINGS LC
摘要:The present invention relates to cosmetic or dermatological compositions containing PQQ or its esters, methods of treating or promoting skin changes by topical application of these compositions, and methods of synthesis of PQQ esters. The PQQ ester-containing compositions of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the PQQ esters of the present invention have an antioxidant effect that is useful in treating a skin change.

专利号:US-5654441-A
优先权日:1995-09-14
标 题 :Synthesis of 1,3-oxathiolane sulfoxide compounds
发明人：MCPHEE DEREK JAMES
权利人:UNIROYAL CHEMICAL LTD
摘要:A process for the production of a 1,3-oxathiolane sulfoxide of the formula ##STR1## wherein X is an amino group of the formula --NHR, wherein R is hydrogen, phenyl, C 1 -C 8 alkyl, C 3 -C 6 cycloalkyl, nitrophenyl, (C 1 -C 4 alkoxy)phenyl, furfuryl, halophenyl, tolyl, napthyl, biphenyl or hydroxyphenyl; or X is an alkoxy group of the formula --OR 1 wherein R is C 1 -C 6 alkyl, n which process comprises oxidizing a 1,3-oxathiolane of the formula ##STR2## wherein X is as defined above, in the presence of an effective amount of aqueous hydrogen peroxide and a sterically-hindered organoselenium compound of the formula ##STR3## wherein R 2 is aryl, mono-, di- or tri-substituted with C 1 -C 3 alkyl, n to the produce the 1,3-oxathiolane sulfoxide. This process stereoselectively produces the cis stereoisomer of the 1,3-oxathiolane sulfoxide. Additionally, there is disclosed a novel method for the preparation of 5,6-dihydro-2-methyl-1,4-oxathiin compounds using this process.

专利号:US-4286091-A
优先权日:1980-05-19
标 题:Synthesis of pyridazinone pharmaceutical intermediates using diketene reactant
发明人：BIMBER RUSSELL M; BUCHMAN RUSSELL; DEPOMPEI MICHAEL F; POWERS LARRY J
权利人:DIAMOND SHAMROCK CORP
摘要:Valuable pyridazinone intermediates to pharmaceutically useful compounds can be prepared in surprisingly high yields by the reaction of the corresponding monohydrazone with diketene, preferably in the presence of a basic catalyst. In an especially preferred embodiment, p,p'-dichlorobenzil monohydrazone and diketene are reacted in a xylene solvent in the presence of triethylamine to afford 4-acetyl-5,6-bis(p-chlorophenyl)-2H-pyridazin-3-one, which can then be reacted with ethylene carbonate in the presence of potassium carbonate to afford the antihypertensive agent, 4-acetyl-5,6-bis(p-chlorophenyl)-2-(2'-hydroxyethyl)-2H-pyridazine-3-one.

专利号:US-4281125-A
优先权日:1980-05-15
标题:Quinoline catalyzed synthesis of pyridazinone pharmaceutical intermediates
发明人：DEPOMPEI MICHAEL F; HLYNSKY ALEX
权利人:DIAMOND SHAMROCK CORP
摘要:Valuable pyridazinone intermediates to pharmaceutically useful compounds can be prepared in surprisingly high yields by the quinoline catalyzed reaction of the corresponding monohydrazone with an appropriately substituted acetic acid ester. In an especially preferred embodiment, p,p'-dichlorobenzil monohydrazone and methyl acetoacetate are reacted in a xylene solvent in the presence of quinoline to afford 4-acetyl-5,6-bis(p-chlorophenyl)-2H-pyridazin-3-one, which can then be reacted with ethylene carbonate in the presence of potassium carbonate to afford the antihypertensive agent, 4-acetyl-5,6-bis(p-chlorophenyl)-2-(2'-hydroxyethyl)-2H-pyridazin-3-one.

专利号:US-4104140-A
优先权日:1972-10-05
标题:Process for the electrochemical synthesis of organic metal compounds
发明人：EISENBACH WILHELM; LEHMKUHL HERBERT; WILKE GUNTHER
权利人:STUDIENGESELLSCHAFT KOHLE MBH
摘要:Process for reacting an H-acidic organic compound, in which the acidic H-atom is bonded to the organic radical by an oxygen or a sulphur atom, e.g. an alcohol, with a metal having a standard potential which is more positive than -1.66 volts and which at most incompletely reacts with the H-acidic compound under current-free conditions, e.g. Ni, Co, Fe, Mn, Sb, Cu, or Au. The H-acidic compound or a solution thereof is a polar solvent is made conducting by addition of a soluble salt of chlorine, bromine or iodine, and is electrolyzed at a temperature of up to 150° C, using said metal as the anode, for production of the alcoholate.