专利号:US-10801033-B2 优先权日:2016-04-05 标题 :Recombinant polynucleotide involved in lactone synthesis and process for synthesis of lactones thereof 发明人:GUPTA VIDYA SHRIKANT; DESHPANDE ASHISH BALWANT; OAK PRANJALI SUDHIR; GIRI ASHOK PRABHAKAR 权利人:COUNCIL SCIENT IND RES 摘要:The present invention provides the polynucleotide encoding enzyme involved in lactone synthesis and a process for synthesis of lactones using said polynucleotides. The invention also provides recombinant plasmid expression vector comprising said polynucleotide sequence. The recombinant protein encoded by said polynucleotides leads to synthesis of lactones having flavour peculiar to Alphonso mangoes.
专利号:US-9643915-B2 优先权日:2013-03-15 标题:Methods for the synthesis of sphingomyelins and dihydrosphingomyelins 发明人:ONICIU DANIELA CARMEN; HECKHOFF STEFAN; OSWALD BENOIT; REBMANN PETER; PEER ANDREAS; GONZALEZ MIGUEL; SAUTER PATRIK 权利人:CERENIS THERAPEUTICS HOLDING SA 摘要:The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides.
专利号:US-9708354-B2 优先权日:2013-03-15 标 题:Methods for the synthesis of sphingomyelins and dihydrosphingomyelins 发明人:ONICIU DANIELA CARMEN; HECKHOFF STEFAN; OSWALD BENOIT; REBMANN PETER; PEER ANDREAS; GONZALEZ MIGUEL; SAUTER PATRIK 权利人:CERENIS THERAPEUTICS HOLDING SA 摘要:The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides.
专利号:US-4277610-A 优先权日:1975-01-27 标 题 :Synthesis of 2,6,10-trimethyl-undecan-1-ol 发明人:COHEN NOAL; SAUCY GABRIEL 权利人:HOFFMANN LA ROCHE 摘要:A synthesis of 2,6,10-trimethyl-undecan-1-ol, an intermediate for producing vitamin E, from methacrolein, crotonaldehyde, β-hydroxy-isobutyric acid including intermediates in this synthesis.
专利号:US-9783549-B2 优先权日:2013-11-04 标题:Macrocyclization reactions and intermediates useful in the synthesis of analogs of halichondrin B 发明人:FANG FRANCIS G; KIM DAE-SHIK; CHOI HYEONG-WOOK; CHASE CHARLES E; LEE JAEMOON 权利人:EISAI R&D MAN CO LTD 摘要:The invention provides methods for the synthesis of eribulin or a pharmaceutically acceptable salt thereof (e.g., eribulin mesylate) through a macrocyclization strategy. The macrocyclization strategy of the present invention involves subjecting a non-macrocyclic intermediate to a carbon-carbon bond-forming reaction (e.g., an olefination reaction (e.g., Homer-Wadsworth-Emmons olefination), Dieckmann reaction, catalytic Ring-Closing Olefin Metathesis, or Nozaki-Hiyama-Kishi reaction) to afford a macrocyclic intermediate. The invention also provides compounds useful as intermediates in the synthesis of eribulin or a pharmaceutically acceptable salt thereof and methods for preparing the same.
专利号:US-4163021-A 优先权日:1975-01-27 标 题 :Synthesis of 2,6,10-trimethyl-undecan-1-ol 发明人:COHEN NOAL; SAUCY GABRIEL 权利人:HOFFMANN LA ROCHE 摘要:A synthesis of 2,6,10-trimethyl-undecan-1-ol, an intermediate for producing vitamin E, from methacrolein, crotonaldehyde, β-hydroxy-isobutyric acid including intermediates in this synthesis.
[参考文献]: Hirotomo Kihara, Et Al. Arachidonic Acid-Dependent Carbon-Eight Volatile Synthesis From Wounded Liverwort (Marchantia Polymorpha). Phytochemistry. 2014 Nov:107:42-9. [参考文献]: Jun Tabata, Et Al. Olfactory Cues From Plants Infected By Powdery Mildew Guide Foraging By A Mycophagous Ladybird Beetle. Plos One. 2011;6(8):E23799. [参考文献]: M E Nehme, Et Al. Development And Evaluation Of A Trapping System For Anoplophora Glabripennis (Coleoptera: Cerambycidae) In The United States. Environ Entomol. 2014 Aug;43(4):1034-44. [参考文献]: Martin Pareja, Et Al. Herbivory By A Phloem-Feeding Insect Inhibits Floral Volatile Production. Plos One. 2012;7(2):E31971. [参考文献]: Matthias Erb, Et Al. A Tritrophic Signal That Attracts Parasitoids To Host-Damaged Plants Withstands Disruption By Non-Host Herbivores. Bmc Plant Biol. 2010 Nov 15:10:247.
合成参考文献
摘要:Kantchev, E. A. B.; Organ, M. G., Science of Synthesis, (2009) 48, 76. 摘要:Kantchev, E. A. B.; Organ, M. G., Science of Synthesis, (2009) 48, 38. 摘要:Food and Cosmetics Toxicology., 11(95), 1973 [] 摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118 摘要:International Journal of Toxicology 31(Suppl. 1):112-136, 2012