CAS: 83-64-7; 4-Amino-5-Hydroxynaphthalene-1-Sulfonic Acid

该化合物是一种芳香磺酸,其特点是氯化萘环结构,形成疏水性能.酸一般是一种白色到浅黄色晶状固体,在水和有机溶剂中可溶解,主要用作染色中间体和各种化学化合物的合成,包括表面活性剂和药物.全氟辛烷磺酸组的存在具有酸性,使其在水溶液中成为强酸.此外,由于环的富电性,酸可以参与电子生物替代反应.安全考虑包括谨慎处理,因为它可能会刺激皮肤和眼睛.

结构式图片

相似化合物

117-59-9 130-23-4 573-07-9

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4-aminonaphthalene-1,5-disulfonic acid 4,5-diamino-1-naphthalenesulfonic acid acetone 4,5-dihydroxy-1-naphthalene-sulfonic acid p-toluidino-naphthalene-1-sulfonic acid5-hydroxy-4-p-toluidino-naphthalene-1-sulfonic acid 4-anilino-5-hydroxy-naphthalene-1-sulfonic acid 6,6'-(3,3'-dimethoxy-biphenyl-4,4'-diyl)bis(azo)bis(4-amino-5-hydroxynaphthalene-1-sulfonic acid)

合成工艺路线路线简述

    4-氨基萘-1,5-二磺酸置于氢氧化钾,水体系中,化学反应生成 1-氨基-8-萘酚-4-磺酸
    参考文献:De75317
    标题:De75317

    海关参考信息

    专利信息


    专利号:US-9506095-B2
    优先权日:2012-02-09
    标 题:Process for the enzymatic synthesis of (7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid or esters thereof, and application in the synthesis of ivabradine and salts thereof
    发明人:PEDRAGOSA-MOREAU SANDRINE; LEFOULON FRANÇOIS
    权利人:SERVIER LAB; LES LABORATORIES SERVIER
    摘要:Process for the enzymatic synthesis of the compound of formula (I): n nwherein R 1 represents a hydrogen atom or an alkyl group.n n Application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid.

    专利号:US-9476071-B2
    优先权日:2013-02-28
    标 题 :Process for the enzymatic synthesis of (7S)-3,4-dimethoxybicyclo[4.2.0]OCTA-1,3,5-triene-7-carboxylic acid and application in the synthesis of ivabradine and salts thereof
    发明人:PEDRAGOSA-MOREAU SANDRINE; LEFOULON FRANÇOIS
    权利人:SERVIER LAB
    摘要:Process for the enzymatic synthesis of the compound of formula (I): n ncomprising enantioselective enzymatic hydrolysis of the nitrile of formula (IV):n n nusing the nitrilase of Rhodococcus rhodochrous of EMBL accession number EF467367.1, and the application of such a process in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid.

    专利号:US-4000169-A
    优先权日:1975-01-27
    标题 :Asymmetric synthesis of optically active compounds
    发明人:CHAN KA-KONG; SAUCY GABRIEL
    权利人:HOFFMANN LA ROCHE
    摘要:Asymmetric synthesis of optically active 3,7,11-trimethyl-dodecan-1-ol, an intermediate for producing optically active vitamin E, from isovaleraldehyde or prenal including intermediates in this synthesis.

    专利号:US-6610855-B2
    优先权日:1999-03-22
    标题:Synthesis of 3-amino-3-aryl propanoates
    发明人:ABDEL-MAGID AHMED F; COHEN JUDITH H; MARYANOFF CYNTHIA A; VILLANI JR FRANK JOHN; ZHONG HUA M
    权利人:MCNEIL PHARMACEUTICAL INC
    摘要:A process for the synthesis of a compound of the formulawherein R1 is aryl, heteroaryl, substituted aryl or substituted heteroaryl and R2 is hydrogen, alkyl or aralkyl, or salt thereof.

    专利号:US-10239836-B2
    优先权日:2014-10-01
    标题 :Benzenecarbothioccyclopenta[c] pyrrole-1,3-dione compounds and process for synthesis thereof
    发明人:REDDY DUMBALA S; PHILKHANA SATISH C; JACHAK GORAKHNATH R; GUNJAL VIDYA B
    权利人:COUNCIL SCIENT IND RES
    摘要:The present invention provides a novel process for synthesis of nitrosporeusines A(1) and B(2). More particularly, the present invention provides a synthetic route for synthesis of nitrosporeusines A(1) and B(2). Said process is simple, industrially scalable, cost effective and eco-friendly.

    专利号:US-4160865-A
    优先权日:1975-01-27
    标题:Asymmetric synthesis
    发明人:CHAN KA-KONG; SAUCY GABRIEL
    权利人:HOFFMANN LA ROCHE
    摘要:Asymmetric synthesis of optically active 3,7,11-trimethyl-dodecan-1-ol, an intermediate for producing optically active vitamin E, from isovaleraldehyde or prenal including intermediates in this synthesis.
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    合成参考文献


    摘要:Prehled Prumyslove Toxikologie; Organicke Latky, Marhold, J., Prague, Czechoslovakia, Avicenum, 1986, -(1057), 1986
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