CAS: 6336-32-9; 5,11-Dihydroindolo[3,2-B]Carbazole

相似化合物

200339-30-6 243-28-7 194-59-2

上下游产品

2,2-dichloro-1-[2-(1H-indol-3-ylmethyl)-1H-indol-3-yl]-ethanone urorosein cyclohexane-1,4-dione bis(phenylhydrazone) Indole-3-carboxaldehydeIndolo[3,2-b]carbazole 5,11-bis(4-dodecylphenyl)indolo[3,2-b]carbazole 5,11-diethylindolo[3,2-b]carbazole 5,11-bis(2-nitrophenyl)-5,11-dihydroindolo[3,2-b]carbazole

1,4-二溴-2,5-二硝基苯置于pd(Pph3)4 Sodium Carbonate,亚磷酸三乙酯体系中,用 水,甲苯 作为反应溶剂,化学反应 72.0H,反应生成 吲哚并[3,2-B]咔唑
参考文献:Kistenmacher,Axel; Muellen,Klaus,Journal Of Heterocyclic Chemistry,1992,Vol. 29,# 5,P. 1237-1239
标题:Kistenmacher,Axel; Muellen,Klaus,Journal Of Heterocyclic Chemistry,1992,Vol. 29,# 5,P. 1237-1239

专利信息

专利号:US-7241900-B2
优先权日:2002-02-12
标题 :Synthesis of indole thiazole compounds as ligands for the Ah receptor
发明人：DELUCA HECTOR F; GRZYWACZ PAWEL K; SICINSKI RAFAL R
权利人:WISCONSIN ALUMNI RES FOUND
摘要:A method of synthesizing aromatic ketone compositions of formula I comprising the step of introducing a double bond into the 5 membered ring of the 4,5-dihydro-1,3-azoles moiety of formula II is disclosed. A method of synthesizing aromatic ketone compositions of formula I comprising the step of ring synthesis of the tetrahydro-1,3-azoles of formula XI is also disclosed.

专利号:US-9969686-B2
优先权日:2014-08-05
标 题 :Synthesis of diindolylmethanes and indolo[3,2-b]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them
发明人：TANG WEIPING; LI XIAOXUN; SHU DONGXU; WINSTON-MCPHERSON GABRIELLE N
权利人:WISCONSIN ALUMNI RES FOUND
摘要:Described is a method to make diindolylmethanes and indolyl/pyrrolylmethanes, The method includes the steps of contacting an ether comprising an arylpropargyl moiety and an amine-protected, substituted or unsubstituted aniline moiety with a substituted or unsubstituted indol or a substituted or unsubstituted pyrrole, in the presence of a metal-containing catalyst, for a time and at a temperature to cause an annulation/arylation cascade reaction that yields a diindolylmethane or a indolyl/pyrrolylmethane. The resulting compounds are effective to modulate activity of arylhydrocarbon receptors, to inhibit activity of PCSK9, and to stimulate secretion of glucagon-like peptide 1 in mammals.

专利号:US-2004204588-A1
优先权日:2002-02-12
标题 :Synthesis of indole thiazole compounds as ligands for the Ah receptor

专利号:US-7666897-B2
优先权日:2002-08-20
标题 :Analogs of indole-3-carbinol metabolites as chemotherapeutic and chemopreventive agents
发明人：JONG LING; CHAO WAN-RU
权利人:STANFORD RES INST INT
摘要:Novel compounds useful as chemotherapeutic and chemopreventive agents are provided. The compounds are analogs of indole-3-carbinol metabolites wherein the structures and substituents of the compounds are selected to enhance the compounds' overall efficacy, particularly with respect to therapeutic activity, oral bioavailability, long-term safety, patient tolerability, and therapeutic window. The compounds are useful not only in treatment of cancer but also in prevention of cancer. One preferred class of the novel compounds has the structure of formula (IV) n nwherein:n R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 5A , R 6A , R 7A , R 8A , R 22 and R 23 are defined herein. Pharmaceutical compositions are provided as well, as are methods of synthesis and use.

专利号:EP-1480951-A1
优先权日:2002-02-12
标题:Synthesis of indole thiazole compounds as ligands for the ah receptor

专利号:WO-03068742-A1
优先权日:2002-02-12
标题:Synthesis of indole thiazole compounds as ligands for the ah receptor