CAS: 91424-40-7; 3-(Tert-Butyldimethylsilyloxy)Glutaric Anhydride

• 英文名称3-(Tert-Butyldimethylsilyloxy)Glutaric Anhydride
• 中文名称3-叔丁基二甲硅氧基戊二酸酐
• IUPAC名称4-((tert-butyldimethylsilyl)oxy)dihydro-2H-pyran-2,6(3H)-dione
• 其它别名3-叔丁基二甲基硅氧基戊二酸酐; 4-{[tert-Butyl(Dimethyl)Silyl]Oxy}Dihydro-2H-Pyran-2,6(3H)-Dione
• CAS编号91424-40-7
• MFCD编号:MFCD00075235
• EINECS号:618-749-2
• 分子式:C11H20O4Si
• 分子量:244.36
• 产品CID: 1950170
• 产品分类有机原料→分子砌块→脂肪杂环类化合物→四氢吡喃类化合物

• 相似结构搜索
• InChIKey: RXAJGRHLLRGVSB-UHFFFAOYSA-N
• InChI=1S/C11H20O4Si/c1-11(2,3)16(4,5)15-8-6-9(12)14-10(13)7-8/h8H,6-7H2,1-5H3…
• 计算化学: 氢键受体数4.0氢键供体数0.0可旋转键数2.0

相似化合物

物理性质

• 熔点79-81°C
• 沸点302.4°C at 760 mmHg
• 闪点>113°(235°F)
• 密度1.030
• PSA:52.6
• LogP:2.2404
• 折射率1.4510
• 敏感性易受潮
• 外观形态固体
• 储存条件2-8°C
• 产品应用该化合物用于制作标签试剂的起始材料.

MSDS等安全信息

• GHS象形图
• GHS符号GHS07;
  注释: Exclamation mark
• 危险类别特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
  水生慢性毒性 类别2
• 警示词Warning(警告)
• 危险描述H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
  H411 |对水生生物有毒并具有长期持续影响.
• 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
• UN编号NONH for all modes of transport
• 危险品标志Xi
• 安全声明26-37/39
• 危险类别码36/37/38
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 18162-48-6 + 10521-08-1 = 91424-40-7
  反应条件:1.1 Reagents: Hydrogen Catalysts: Ruthenium Solvents: Chloroform; 3 H,1 Mpa,30 °C1.2 Reagents: Imidazole Solvents: Chloroform; 24 H,20 - 30 °C
  标题:Synthesis Of 3-[(Tert-Butyldimethylsilyl)Oxy]Glutaric Anhydride From Citric Acid
  作者:Jiang,C. J.; Et Al
  参考文献:Asian Journal Of Chemistry 日期:2014 卷标:26(22) 页码:7867-7868]
  
  = 91424-40-7 [标题:Reaction Conditions
  标题:Axial Preference Of Bulky Group- And Electron-Withdrawing Group-Substituted Oxygen Atom On The Chair-Type-Cyclohexanone,-Glutaric Anhydride,And -Glutarimide
  作者:Nagao,Yoshimitsu; Et Al
  参考文献:Chemistry Letters 日期:1990 卷标:(9) 页码:1503-6]
  
  18162-48-6 + 7250-55-7 = 91424-40-7
  反应条件:1.1 Reagents: Imidazole Solvents: Xylene; Rt -> 70 °C1.2 Solvents: Xylene; 15 Min,70 °C; 8 H,70 °C; 70 °C -> Rt2.1 Reagents: Sodium Hydroxide Solvents: Methanol; 18 H,Rt2.2 Reagents: Sulfuric Acid Solvents: Ethyl Acetate,Water; Rt -> 15 °C; Ph 3.0 - 3.5,15 °C3.1 Reagents: Acetic Anhydride Solvents: Benzene; Rt -> Reflux; 4 H,Reflux
  标题:Synthesis Of 3-(Tert-Butyldimethylsilyloxy) Glutaric Anhydride
  作者:Jiang,Cheng-Jun; Et Al
  参考文献:Zhejiang Keji Xueyuan Xuebao 日期:2008 卷标:20(2) 页码:107-109]
  
  89-78-1 + 29736-80-9 = 91424-40-7
  反应条件:1.1 Solvents: Toluene; Overnight,Reflux2.1 -3.1 -
  标题:A Practical Synthesis Of Rosuvastatin And Other Statin Intermediates
  作者:Tartaggia,Stefano; Et Al
  参考文献:European Journal Of Organic Chemistry 日期:2015 卷标:2015(19) 页码:4102-4107]
  
  113794-48-2 = 91424-40-7
  反应条件:1.1 Reagents: Acetic Anhydride Solvents: Benzene; Rt -> Reflux; 4 H,Reflux
  标题:Synthesis Of 3-(Tert-Butyldimethylsilyloxy) Glutaric Anhydride
  作者:Jiang,Cheng-Jun; Et Al
  参考文献:Zhejiang Keji Xueyuan Xuebao 日期:2008 卷标:20(2) 页码:107-109]
  
  91424-39-4 = 91424-40-7
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Methanol; 38 H,Rt1.2 Reagents: Acetic Anhydride Solvents: Benzene; 1.5 H,Reflux1.3 Reagents: Water
  标题:Toward The Total Synthesis Of Lophotoxin - New Methodologies And Synthetic Strategies
  作者:Wipf,Peter; Et Al
  参考文献:Canadian Journal Of Chemistry 日期:2006 卷标:84(10) 页码:1226-1241]
  
  18162-48-6 + 152294-14-9 = 91424-40-7
  反应条件:1.1 Reagents: Imidazole Solvents: Chloroform; 24 H,20 - 30 °C
  标题:Synthesis Of 3-[(Tert-Butyldimethylsilyl)Oxy]Glutaric Anhydride From Citric Acid
  作者:Jiang,C. J.; Et Al
  参考文献:Asian Journal Of Chemistry 日期:2014 卷标:26(22) 页码:7867-7868]
  
  = 91424-40-7 [标题:Reaction Conditions
  标题:Synthesis Of Gabob And Gabob-Based Chiral Units Possessing Distinct Protecting Groups
  作者:Ivsic,Trpimir; Et Al
  参考文献:European Journal Of Organic Chemistry 日期:2014 卷标:2014(3) 页码:631-638]
  
  10521-08-1 = 91424-40-7
  反应条件:1.1 Reagents: Hydrogen Catalysts: Ruthenium Solvents: Chloroform; 3 H,1 Mpa,30 °C2.1 Reagents: Imidazole Solvents: Chloroform; 24 H,20 - 30 °C
  标题:Synthesis Of 3-[(Tert-Butyldimethylsilyl)Oxy]Glutaric Anhydride From Citric Acid
  作者:Jiang,C. J.; Et Al
  参考文献:Asian Journal Of Chemistry 日期:2014 卷标:26(22) 页码:7867-7868]
  
  112904-68-4 = 91424-40-7
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Methanol; 18 H,Rt1.2 Reagents: Sulfuric Acid Solvents: Ethyl Acetate,Water; Rt -> 15 °C; Ph 3.0 - 3.5,15 °C2.1 Reagents: Acetic Anhydride Solvents: Benzene; Rt -> Reflux; 4 H,Reflux
  标题:Synthesis Of 3-(Tert-Butyldimethylsilyloxy) Glutaric Anhydride
  作者:Jiang,Cheng-Jun; Et Al
  参考文献:Zhejiang Keji Xueyuan Xuebao 日期:2008 卷标:20(2) 页码:107-109]
  
  1808254-55-8 = 91424-40-7 [标题:Reaction Conditions
  标题:A Practical Synthesis Of Rosuvastatin And Other Statin Intermediates
  作者:Tartaggia,Stefano; Et Al
  参考文献:European Journal Of Organic Chemistry 日期:2015 卷标:2015(19) 页码:4102-4107]
  
  542-05-2 = 91424-40-7
  反应条件:1.1 Reagents: Acetic Anhydride; 3 H,0 °C2.1 Reagents: Hydrogen Catalysts: Ruthenium Solvents: Chloroform; 3 H,1 Mpa,30 °C2.2 Reagents: Imidazole Solvents: Chloroform; 24 H,20 - 30 °C
  标题:Synthesis Of 3-[(Tert-Butyldimethylsilyl)Oxy]Glutaric Anhydride From Citric Acid
  作者:Jiang,C. J.; Et Al
  参考文献:Asian Journal Of Chemistry 日期:2014 卷标:26(22) 页码:7867-7868

海关参考信息

• 2905122000-异丙醇
  2905399001-1,3-丙二醇
  2909110000-乙醚
  2912110000-甲醛
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