专利号:WO-2010017526-A1 优先权日:2008-08-08 标题 :Purine nucleotides isotopically labeled in the purine base, methods of making thereof and uses thereof 发明人:WILLIAMSON JAMES R; SCHULTHEISZ HEATHER; SCOTT LINCOLN G 权利人:SCRIPPS RESEARCH INST; WILLIAMSON JAMES R; SCHULTHEISZ HEATHER; SCOTT LINCOLN G 摘要:The present invention provides purine nucleotides isotopically labeled in the purine base, methods of making thereof and uses thereof, for example, in biochemical and biophysical studies of nucleic acid structure and function. Also provided is a method of synthesizing 13 C-10-formyl-tetrahydrofolate and a method of for immobilizing recombinant enzymes of the pentose phosphate pathway and the denovo purine synthesis pathway with fusion affinity domains attached to a metal chelate resin.
摘要:Merck Index - O'Neil MJ, Heckelman PE, Dobbelaar PH, Roman KJ (eds). The Merck Index, An Encyclopedia of Chemicals, Drugs, and Biologicals, 15th Ed. Cambridge, UK: The Royal Society of Chemistry, 2013.