CAS: 13473-01-3; 5-Chloro-2-Methoxypyridine

相似化合物

22109-30-4 13472-58-7 282723-23-3

上下游产品

CAS号2457-47-8 3,5-二氯吡啶 | CAS号16110-09-1 2,5-二氯吡啶 | CAS号13472-85-0 5-溴-2-甲氧基吡啶 | CAS号124-41-4 甲醇钠 | CAS号67-56-1 甲醇 | CAS号1628-89-3 2-甲氧基吡啶 | CAS号102830-80-8 6-chloro-2-(4-c... | CAS号475275-69-5 2-甲氧基-5-氯吡啶-4-硼酸 | CAS号74115-12-1 5-氯-3-羟基吡啶 | CAS号102830-62-6 6-chloro-2-(4-c... | CAS号102830-65-9 6-chloro-2-(3,4... | CAS号102830-75-1 2-甲氧基-3-溴-5-氯吡啶 | CAS号103058-88-4 5-氯-2-甲氧基烟醛 | CAS号16110-09-1 2,5-二氯吡啶 | CAS号15871-85-9 6-甲氧基-3-吡啶甲腈

2,5-二氯吡啶置于sodium Methylate体系中,用 甲醇 用作溶剂,化学反应生成5-氯-2-甲氧基吡啶
参考文献:2-Phenylpyrano[2,3-B]Pyridines And Their Use In Inhibiting Viruses
标题:2-Phenylpyrano[2,3-B]Pyridines And Their Use In Inhibiting Viruses
摘要:本文描述了2-苯基吡喃并[2,3-B]吡啶.这些化合物对各种病毒具有活性.可以使用多种方法来制备本发明的化合物,但在某个阶段,它们都会利用(苯基)(吡啶基)丙醇或(苯基)(吡啶基)丙烯醇的环化.

专利信息

专利号:US-5428166-A
优先权日:1992-06-18
标 题 :Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs
发明人：COMINS DANIEL L
权利人:UNIV NORTH CAROLINA STATE
摘要:A method of making racemic DE ring intermediates for the synthesis of camptothecin and camptothecin analogs employing novel intermediates of Formula XX and XXI: ##STR1## as precursors to the DE ring intermediate. The present invention also provides camptothecin analog of Formula I-A ##STR2## wherein: Hal is a halogen is selected from the group consisting of F, Cl, and Br; n R may be loweralkyl; n R 1 may be H, loweralkyl, loweralkoxy, or halo; n R 2 , R 3 , R 4 , and R 5 may each independently be H, amino, hydroxy, loweralkyl, loweralkoxy, loweralkyl-thio, di(loweralkyl)amino, cyano, methylenedioxy, formyl, nitro, halo, trifluoromethyl, amninomethyl, azido, amido, hydrazino, or any of the twenty standard amino acids bonded to the A ring via the amino-nitrogen atom. n Additionally, novel compounds useful in the preparation of the compounds of Formula I-A are also provided.

专利号:US-5459269-A
优先权日:1992-06-18
标 题:14-halo-camptothecins
发明人：COMINS DANIEL L
权利人:UNIV NORTH CAROLINA STATE
摘要:A method of making racemic DE ring intermediates for the synthesis of camptothecin and camptothecin analogs employing novel intermediates of Formula (XX) and (XXI): ##STR1## wherein R 20 is loweralkyl, R is loweralkyl, Y is H or halogen, and R 21 is loweralkoxy; as precursors to the DE ring intermediate. n The present invention also provides a camptothecin analog of Formula (I-A): ##STR2## wherein: Hal is a halogen; n and the remainder of the variables are as defined in the specification. n Additionally, other novel compounds useful in the preparation of the compounds of Formula (I-A) and methods of producing compounds of (I-A) are also provided.

专利号:US-8466287-B2
优先权日:2005-06-09
标题 :Process for producing tricyclic ketone
发明人：NISHIYAMA HIROYUKI; SAWADA SEIGO
权利人:NISHIYAMA HIROYUKI; SAWADA SEIGO; YAKULT HONSHA KK
摘要:In order to efficiently supply CPT, which is a starting compound of irinotecan hydrochloride and a variety of camptothecin derivatives, by a practical total synthesis, the invention provides a means of efficiently preparing a tricyclic ketone that corresponds to a CDE ring moiety of a camptothecin (CPT) skeleton.

专利号:WO-2024115549-A1
优先权日:2022-11-30
标题:Aryl- and heteroaryl-sulfonamide derivatives as ccr8 modulators
发明人：AISSAOUI HAMED; CORMINBOEUF OLIVIER; DIETHELM STEFAN; REMEN LUBOS; RICHARD-BILDSTEIN SYLVIA
权利人:IDORSIA PHARMACEUTICALS LTD
摘要:The present invention relates to compounds of Formula (I), their synthesis and use as CCR8 receptor modulators in medicine.