CAS: 22832-87-7; Miconazole Nitrate

专利信息

专利号:US-8557979-B2
优先权日:2004-06-10
标题 :Carbapenem antibacterials with gram-negative activity and processes for their preparation
发明人：CHOI WOO-BAEG; KOWALIK EWA
权利人:CHOI WOO-BAEG; KOWALIK EWA; FOB SYNTHESIS INC
摘要:The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of β-methyl carbapenems which are useful as antibacterial agents.

专利号:US-10933051-B2
优先权日:2017-06-09
标 题 :Carbapenem compounds and compositions for the treatment of bacterial infections
发明人：CHOI WOO-BAEG; TOMIOKA TAKASHI; JOO HYUNG-YEUL; TRUONG PHONG; MIN BRIAN
权利人:FOB SYNTHESIS INC
摘要:The present invention provides carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections, including drug resistant or multiple-drug resistant bacterial infections, and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.

专利号:US-9382288-B2
优先权日:2010-10-06
标题 :Derivatives of steroid benzylamines, having an antiparasitic antibacterial, antimycotic and/or antiviral action
发明人：BECKER KATJA; KRIEG REIMAR; SCHÖNECKER BRUNO
权利人:BECKER KATJA; KRIEG REIMAR; SCHÖNECKER BRUNO; UNIV GIESSEN JUSTUS LIEBIG
摘要:The present invention relates to compounds derived from steroids of the general formula (I) n nwherein L represents a linker and R # represents a steroid residue, the use of compounds of the general formula (I) in medicine and for the prophylaxis and/or the treatment of infectious diseases. Furthermore described are pharmaceutical compositions containing at least one compound of the general formula (I). A further aspect of the invention relates to the synthesis of said compounds of the general formula (I).

专利号:US-9327264-B2
优先权日:2011-01-31
标 题 :Containerless synthesis of amorphous and nanophase organic materials
发明人：BENMORE CHRIS J; WEBER JOHANN R
权利人:BENMORE CHRIS J; WEBER JOHANN R; UCHICAGO ARGONNE LLC
摘要:The invention provides a method for producing a mixture of amorphous compounds, the method comprising supplying a solution containing the compounds; and allowing at least a portion of the solvent of the solution to evaporate while preventing the solute of the solution from contacting a nucleation point. Also provided is a method for transforming solids to amorphous material, the method comprising heating the solids in an environment to form a melt, wherein the environment contains no nucleation points; and cooling the melt in the environment.

专利号:WO-2009026858-A1
优先权日:2007-08-28
标题 :Derivatives of acridinone as anti-parasitic, anti-fungal and anti-viral agents
发明人：PELLON CONDOM ROLANDO F; DOCAMPO PALACIOS MAITE L; PARDO ANDREU GILBERTO L; FERNANDEZ-CALIENES VALDES AYME; MENDIOLA MARTINEZ BARBARA JUDITH; ROJAS RIVERO LAZARA; D ACCORSO HAICCK NORMA BEATRIZ; FASCIO SILVA MIRTA LILIANA; DAMONTE LOTITO ELSA BEATRIZ; GARCIA CATTEBEKE CYBELE CARINA; SEPULVEDA SUCHECKI CLAUDIA SOLEDAD; MAZZUCCO GAVIEIRO MARIA BELEN; TALARICO SALINAS LAURA BEATRIZ; MAES LOUIS
权利人:CT DE QUIMICA FARMACEUTICA; PELLON CONDOM ROLANDO F; DOCAMPO PALACIOS MAITE L; PARDO ANDREU GILBERTO L; FERNANDEZ-CALIENES VALDES AYME; MENDIOLA MARTINEZ BARBARA JUDITH; ROJAS RIVERO LAZARA; D ACCORSO HAICCK NORMA BEATRIZ; FASCIO SILVA MIRTA LILIANA; DAMONTE LOTITO ELSA BEATRIZ; GARCIA CATTEBEKE CYBELE CARINA; SEPULVEDA SUCHECKI CLAUDIA SOLEDAD; MAZZUCCO GAVIEIRO MARIA BELEN; TALARICO SALINAS LAURA BEATRIZ; MAES LOUIS
摘要:The invention relates to the synthesis and evaluation of novel organic products as anti-parasitic, anti-fungal and anti-viral agents. More specifically, the invention relates to novel derivatives of 10-alyl- (I), 10-(3methyl-2-butenyl)- (II) and 10-(1,2propanodienyl)-9(10H)-acridinone (III) and a novel family of acridinones, 10-{[3-(6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-il)-4,5-dihydro-5-isoxazolyl] methyl}-9(10H) acridinone (IV) having the following formulas: wherein positions 1, 2, 3, 4, 5, 6, 7 and 8 of the acridinone ring are hydrogen atoms or halogens, groups consisting of hydroxyl, amino, nitro, alkyl with between 1 and 5 carbon atoms, trichloromethyl, trifluoromethyl, alkoxyl with between 1 and 6 carbon atoms (aryloxy substituted), aryl and alkylamino with between 1 and 6 carbon atoms (mono- and di-substituted), aryl and alkylamide with between 1 and 4 atoms of carbon, cyano, carboxyl, formyl, alkyl and arylsulfonic, mercapto substituted with alkylic chains having up to 5 carbon atoms, and sulfoxide aryl. Said derivatives have an activity against Plasmodium falciparum, Trypanosoma brucei and Trypanosoma cruzi protozoans, as well as Microsporum canis and strains of the Junin virus and Dengue.

专利号:US-9937151-B2
优先权日:2010-06-18
标题 :Carbapenem antibacterials with gram-negative activity
发明人：CHOI WOO-BAEG; GRUSZECKA-KOWALIK EWA; JOO HYUNG-YEUL; LIU SHUANGPEI; MAO SHULI; LI YONGFENG; KIM DEOG-IL
权利人:FOB SYNTHESIS INC
摘要:The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.