CAS: 2516-93-0; N-Butoxyacetic Acid

该化合物是一种有机化合物,被归类为箱状酸.它具有一种附于箱状酸功能组的丁氧组(来自丁醇),该组为化学配方C6H12O3.这种无色液体以其中度挥发性而著称,可溶于水,酒精和许多有机溶剂中.丁氧乙酸主要用作各种工业用途的溶剂,包括涂层,油漆和清洁产品,因为它能够溶解多种物质.它表现出低毒性和相对低味等特性,适合用于消费品.然而,必须小心处理,因为它可能会引起皮肤和眼睛的刺激.此外,由于潜在的环境影响,它的使用和处置受管制.

结构式图片

相似化合物

63632-58-6 54497-00-6 7397-62-8

欧盟法规

ECHA物质C&L通报

上下游产品

2-Butoxyethanol 2Etn-Bu°C(H)HCO2Et 2-butoxymethyl-benzothiazole 1-butoxy-2-methyl-propan-2-ol 2-Butoxy-N-{5-[4-(2-trifluoromethyl benzoyl)piperazin-1-yl][1,3,4]thiadiazol-2-yl}acetamide

合成工艺路线路线简述

    (Tetrahydro-Furan-2-Yloxy)-Acetic Acid Methyl Ester置于platinum(Iv) Oxide 氢氧化钾,氢气体系中,化学反应生成2-丁氧基乙酸
    参考文献:5-氧代-3-氧杂戊烷羧酸酯的合成及其环化反应,形成二恶烷酮和吗啉酮的同系物
    标题:5-氧代-3-氧杂戊烷羧酸酯的合成及其环化反应,形成二恶烷酮和吗啉酮的同系物
    摘要:
    Doi:10.1007/bf00755264

    海关参考信息

    专利信息


    专利号:US-9346853-B2
    优先权日:2012-06-20
    标 题 :Synthesis of telaprevir and boceprevir, or pharmaceutically acceptable salts or solvates as well as intermediate products thereof including β-amino acids prepared via Mukaiyama aldol addition
    发明人:HOEFERL-PRANTZ KATHRIN; FELZMANN WOLFGANG; WILHELM THORSTEN; BENITO-GARAGORRI DAVID
    权利人:SANDOZ AG
    摘要:The invention relates to synthetic routes for preparing telaprevir and boceprevir, and its intermediates as well as peptides other than telaprevir. The synthetic routes are based on a Mukaiyama aldol addition reaction of a silyl enol ether or an enolate with an imine. The invention also refers to novel intermediates for preparing telaprevir/boceprevir or other peptides.

    专利号:US-8008526-B2
    优先权日:2005-03-17
    标 题 :Synthesis reaction catalyst and method of synthesizing compound using the same
    发明人:TANAKA HIROHISA; KANEKO KIMIYOSHI
    权利人:DAIHATSU MOTOR CO LTD; HOKKO CHEM IND CO
    摘要:To improve a catalytic activity of a composite oxide, to carry out a reaction in a high yield, and to provide a synthesis reaction catalyst having excellent handling properties and a method of a synthesizing a compound using the same, a synthesis reaction catalyst containing a palladium-containing perovskite-type composite oxide having a specific surface area of 0.5 to 9.5 m 2 /g is used in Suzuki Cross-Couplings given by the following general scheme (14).

    专利号:WO-2006135646-A1
    优先权日:2005-06-10
    标题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators and related methods of synthesis

    专利号:EP-1891040-A1
    优先权日:2005-06-10
    标题 :Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators and related methods of synthesis

    专利号:US-7592473-B2
    优先权日:2005-03-17
    标题:Method of synthesizing compound
    发明人:TANAKA HIROHISA; KANEKO KIMIYOSHI
    权利人:DAIHATSU MOTOR CO LTD; HOKKO CHEM IND CO
    摘要:In order to provide a method of synthesizing a compound in which activity of a catalyst is maintained even when the catalyst is recovered after the completion of the coupling reaction using a palladium-containing perovskite-type composite oxide as the catalyst and used repeatedly and the reaction can be carried out in a high yield, a palladium-containing perovskite-type composite oxide is used as a synthesis reaction catalyst and a reaction solvent containing an alkoxy alcohol is used as a reaction solvent in Suzuki Cross-Couplings given by the following general formula (15).

    专利号:US-2015183824-A1
    优先权日:2012-06-20
    标 题 :SYNTHESIS OF TELAPREVIR AND BOCEPREVIR, OR PHARMACEUTICALLY ACCEPTABLE SALTS OR SOLVATES AS WELL AS INTERMEDIATE PRODUCTS THEREOF INCLUDING beta-AMINO ACIDS PREPARED VIA MUKAIYAMA ALDOL ADDITION
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    合成参考文献


    参考文献:10.1007/s00420-004-0523-4
    摘要:Ben-Brik E, Jérôme L, Arnaud I, Yous S, Labat L, Haguenoer JM, Multigner L. Exposure to glycol ethers in a population of French men evaluated by measurement of urinary alkoxycarboxylic acids. International Archives of Occupational and Environmental Health. 2004 May 26;77(5):368–72. doi: 10.1007/s00420-004-0523-4.
    参考文献:10.1539/joh.46.260
    摘要:Choi HS, Park JH, Song JS, Cho YB. Determination of Urinary Metabolites of Alkyl Cellosolves by Solid Phase Extraction and GC/FID. Journal of Occupational Health. 2004 Jul;46(4):260–5. doi: 10.1539/joh.46.260.
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