CAS: 3489-28-9; 1,9-Nonanedithiol

该化合物是有机化合物,其特点是在非烷链第一和第九碳原子上存在两个硫醇(-SH)功能组,这种结构具有独特的特性,包括大蒜或腐烂蛋的强烈,往往不愉快的味道,这是许多硫柳的典型现象.该化合物在室内温度下是无色的黄色黄色液体,可溶于有机溶剂,但因其水分恐惧性非烷脊椎,在水中溶解性有限. 1,9-诺安尼迪希醇因其活性而闻名,特别是在氧化后形成脱硫剂方面,可用于各种化学合成应用.此外,它可能展示生物活动,引起生物化学化学和材料科学等领域的兴趣.在处理该化合物时,必须采取安全防范措施,因为硫柳物可能有毒,并刺激皮肤和呼吸系统.

结构式图片

相似化合物

1191-62-4 1191-67-9 1191-43-1

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号4549-33-1 1,9-二溴壬烷 | CAS号3937-56-2 1,9-壬二醇

合成工艺路线路线简述

  • 合成目标产物 1,9-Nonanedithiol 主要起始原料 1,9-Nonanediol
  • (文献来源)合成步骤主要原料 1,9-Nonanediol
1,9-二溴壬烷置于sodium Hydrogensulfide,乙醚,乙醇,硫化氢体系中,化学反应生成1,9-壬二硫醇
参考文献:Hall; Reid,Journal Of The American Chemical Society,1943,Vol. 65,P. 1467
标题:Hall; Reid,Journal Of The American Chemical Society,1943,Vol. 65,P. 1467

专利信息


专利号:US-2024309024-A1
优先权日:2023-03-14
标题 :Direct synthesis of alkenylhalosilanes
发明人:LEWIS KENRICK MARTIN; ZHU YANJUN; BYRNE CHRISTOPHER M
权利人:MOMENTIVE PERFORMANCE MAT INC
摘要:A process for the direct synthesis of alkenylhalosilane monomers. Forming a slurry of liquid and copper-activated silicon from fresh silicon, cyclone fines and/or fine dust from silicon grinding, ultrafines and/or spent contact mass from the Direct Synthesis of alkylhalosilanes and arylhalosilanes, in a thermally stable solvent. Reacting the silanes by agitating the slurry with at least one unsaturated aliphatic or cycloaliphatic organohalide of the formula R1X, and optionally an organohalosilane and/or hydrogen halide, in the presence of a polymerization inhibiting Lewis base additive, at a reaction time, temperature and pressure effective to produce alkenylhalosilanes having the formulae, R1SiHX2, R12SiHX, R13SiX, R1SiX3, and R12SiX2 or mixtures thereof.

专利号:US-2019211134-A1
优先权日:2016-08-19
标 题 :Thiourethane polymers, method of synthesis thereof and use in fused filament fabrication printing
发明人:ELLSON GREGORY T; LUND BENJAMIN R; VOIT WALTER
权利人:BOARD OF REGENTS THE UNIV OF TEXAS; ADAPTIVE 3D TECH
摘要:A thermoplastic thiourethane polymer comprising a sequential chain of a first type of monomer covalently bonded to a second type of monomer via thiourethane linkages. The first type of monomer includes two or more thiol functional groups and the type of monomer includes two or more isocyanate functional groups. The first and second types of monomers are polymerized together in an anhydrous aprotic solvent-dissolved anionic step-growth polymerization reaction that is catalyzed by a non-nucleophillic base having a pKa greater than 7.

专利号:US-10899072-B2
优先权日:2016-03-15
标题:Thiourethane polymers, method of synthesis thereof and use in additive manufacturing technologies
发明人:ELLSON GREGORY T; LUND BENJAMIN R; VOIT WALTER
权利人:UNIV TEXAS; ADAPTIVE 3D TECH; BOARD OF RESENTS THE UNIV OF TEXAS SYSTEM
摘要:A semi-crystalline thiourethane polymer. The semi-crystalline thiourethane polymer comprises a sequential chain of a first type of monomer covalently bonded to a second type of monomer via thiourethane linkages. Each of the first type of monomer includes two or more thiol functional groups and each of the second type of monomer includes two or more isocyanate functional groups. The first and second types of monomers are polymerized together in an anionic step-growth polymerization reaction that is catalyzed by a non-nucleophillic base having a pKa greater than 7, produced by photo-initiated decomposition of a photolatent base. A method of synthesizing, and polymer jetting and stereolithography methods of manufacturing a polymer part, are also disclosed.

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

专利号:US-9896776-B2
优先权日:2011-09-21
标 题 :Chemical and electrochemical synthesis and deposition of chalcogenides from room temperature ionic liquids
发明人:STEVENSON KEITH J; MURUGESAN SANKARAN; KEARNS PATRICK; AKKINENI ARUNKUMAR
权利人:UNIV TEXAS
摘要:Room temperature electrochemical methods to deposit thin films of chalcogenide glasses.

专利号:US-11155670-B2
优先权日:2016-08-24
标题:Amorphous thermoset thiourethane polymers, method of synthesis thereof and use in bio-electronic devices
发明人:ELLSON GREGORY T; VOIT WALTER
权利人:UNIV TEXAS
摘要:An amorphous thermoset thiourethane polymer, comprising a sequential chain of a first type of monomer covalently bonded to a second type of monomer via thiourethane linkages, wherein the first type of monomer includes two or more thiol functional groups and the second type of monomer includes two or more isocyanate functional groups. Methods of synthesizing the polymer, bio-electronic devices comprising the polymer and methods of manufacturing such devices are disclosed.
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合成参考文献


摘要:Shinmyozu, T.; Shibahara, M., Science of Synthesis, (2010) 45, 1272.
摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 1985. Acute oral toxicity and repellency of 933 chemicals to house and deer mice. Archives of Environmental Contamination and Toxicology 14:111-129.
摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 2004. Toxicity, Repellency of Phytotoxicity of 979 Chemicals to Birds, Mammals and Plants. Research Report No. 04-01. National Wildlife Research Center, Fort Collins, Colorado. 118 pp.
参考文献:10.1186/s12967-022-03329-3
摘要:Zhai B, Tian H, Sun J, Zou J, Zhang X, Cheng J, Shi Y, Fan Y, Guo D. Urokinase-type plasminogen activator receptor (uPAR) as a therapeutic target in cancer. Journal of Translational Medicine. 2022 Mar 18;20(1):135. doi: 10.1186/s12967-022-03329-3.
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