CAS: 6044-68-4; Acroleindimethylacetal

相似化合物

6068-62-8 4093-49-6 17576-35-1

丙烯醛置于对苯二酚体系中,用 甲醇 作为反应溶剂,化学反应生成 丙烯醛二甲缩醛
参考文献:Process And Apparatus For Producing Alpha,Beta-Unsaturated Acetals
标题:Process And Apparatus For Producing Alpha,Beta-Unsaturated Acetals
摘要:在制备α,β-不饱和缩醛的过程中,通过在反应容器中加入固体催化剂,在α,β-不饱和醛和低级醇反应的过程中,改进包括将离开反应容器的反应产物引入蒸馏柱中,在蒸馏柱的最高阶段到最低阶段之上的某个阶段进行,并将蒸馏柱的馏分回收到反应容器中.

专利信息

专利号:US-2009306400-A1
优先权日:2006-03-27
标 题:Convergent process for the synthesis of taxane derivatives.
发明人：HENRI JOHN T; MCCHESNEY JAMES D; VENKATARAMAN SYLESH K; LAMB RODGER L; FOSTER JONATHAN E; SUMNER CHRISTIAN M; YE SHANGPING
权利人:HENRI JOHN T; MCCHESNEY JAMES D; VENKATARAMAN SYLESH K; LAMB RODGER L; FOSTER JONATHAN E; SUMNER CHRISTIAN M; YE SHANGPING
摘要:The present invention is broadly directed to novel compounds useful for the synthesis of biologically active compounds, including taxane derivatives, and convergent processes for the preparation of these taxane derivatives and their intermediates.

专利号:US-6906214-B2
优先权日:2001-07-04
标题:Preparation of aromatic organozinc compounds and composition therefore
发明人：PERICHON JACQUES; GOSMINI CORINNE; FILLON HYACINTHE
权利人:RHODIA CHIMIE SA
摘要:The invention relates to a technique for preparing aromatic organozinc compounds and to a composition therefore. This composition constitutes a reactant that can be used to carry out the synthesis of organozinc compounds, and comprises a cobalt salt, a zinc salt, a polar aprotic solvent and elemental zinc in divided form, the elemental zinc being in solid form, the other elements being in a form dissolved in the solvent. Application to organic synthesis.

专利号:US-4005131-A
优先权日:1976-01-02
标 题 :Synthesis of oxalate esters from carbon monoxide and acetals or ketals
发明人：ZEHNER LEE R
权利人:ATLANTIC RICHFIELD CO
摘要:A process for the preparation of oxalate esters by the catalytic oxidative carbonylation of acetals and ketals with carbon monoxide and oxygen-containing gas in the presence of a metal salt catalyst, an amine base and a catalytic amount of an alcohol. Preferably a catalytic amount of particular metal oxidizing salts is employed along with a catalytic amount of an acid or an amine salt compound. Alternatively various counterions and ligands of the metal salt catalysts may be employed.

专利号:US-7799756-B2
优先权日:2004-07-29
标题 :Processes for stereoselective synthesis of trans ISATX247
发明人：MOLINO BRUCE F; YANG ZHICAI; MAENG JUN-HO; MANNING DAVID D
权利人:ALBANY MOLECULAR RES INC
摘要:The present invention relates to a process for preparation of a trans ISA TX 247 compound of the formula: where R 1 â•?H or D; R 2 â•?H or D; and R 3 â•?H or D, by application of organozirconium chemistry. The process involves reacting an acetyl cyclosporin aldehyde with an organozirconium reagent to provide acetyl cyclosporin diene (the acetate of trans ISA TX 247) and deacetylating the acetyl cyclosporin diene to produce the trans-isomer of ISA TX 247. The present invention also relates to a process for preparing the same trans ISA TX 247 compound, using olefin cross metathesis. The process involves: olefin cross metathesis of acetyl cyclosporin A to afford acetyl cyclosporin α,β-unsaturated aldehyde; Wittig reaction of the acetyl cyclosporin α,β-unsaturated aldehyde to provide acetyl cyclosporin diene; and deacetylation of the acetyl cyclosporin diene to produce the trans ISA TX 247 compound. Also disclosed are processes for preparing an acetyl cyclosporin α,β-unsaturated aldehyde compound and a cyclosporin triene analogue compound.

专利号:US-7074932-B2
优先权日:1999-06-24
标题 :Preparation of quinoline-substituted carbonate and carbamate derivatives
发明人：ALLEN MICHAEL S; PREMCHANDRAN RAMIYA H; CHANG SOU-JEN; CONDON STEPHEN; DEMATTEI JOHN A; KING STEVEN A; KOLACZKOWSKI LAWRENCE; MANNA SUKUMAR; NICHOLS PAUL J; PATEL HEMANT H; PATEL SUBHASH R; PLATA DANIEL J; STONER ERIC J; TIEN JIEN-HEH J; WITTENBERGER STEVEN J
权利人:ALLEN MICHAEL S; PREMCHANDRAN RAMIYA H; CHANG SOU-JEN; CONDON STEPHEN; DEMATTEI JOHN A; KING STEVEN A; KOLACZKOWSKI LAWRENCE; MANNA SUKUMAR; NICHOLS PAUL J; PATEL HEMANT H; PATEL SUBHASH R; PLATA DANIEL J; STONER ERIC J; TIEN JIEN-HEH J; WITTENBERGER STEVEN J
摘要:The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.

专利号:US-2010069643-A1
优先权日:2005-12-21
标 题:Convergent Process for the Synthesis of Taxane Derivatives
发明人：MCCHESNEY JAMES D; HENRI JOHN T; VENKATARAMAN SYLESH K; LAMB RODGER L; FOSTER JONATHAN E; SUMMER CHRISTIAN M; YE SHANGPING
权利人:MCCHESNEY JAMES D; HENRI JOHN T; VENKATARAMAN SYLESH K; LAMB RODGER L; FOSTER JONATHAN E; SUMMER CHRISTIAN M; YE SHANGPING
摘要:The application provides a process for the preparation of taxane derivatives and intermediates useful in such processes.