CAS: 33075-00-2; (6R,7R)-3-(Acetoxymethyl)-7-(2-((N,N'-Diisopropylcarbamimidoyl)Thio)Acetamido)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid

上下游产品

bromoacetylamin°Cephalosporanic acid 1,3-diisopropylthiourea 7-chloroacetamid°Cephalosporanic acid N,,N-diisopropylthiourea

1,3-二异丙基-2-硫脲,3-[(乙酰氧基)甲基]-7-[(溴乙酰)氨基]-8-氧代-(6R-Trans)-5-硫杂-1-氮杂双环[4,2,0]辛-2-烯-2-羧酸置于三乙胺体系中,用 二氯甲烷 用作溶剂,化学反应 1.5H,以4.4 G的收率获得头孢硫脒
参考文献:一种采用粒子过程晶体产品分子组装与形态优化技术的头孢硫脒新晶型化合物及制剂
标题:一种采用粒子过程晶体产品分子组装与形态优化技术的头孢硫脒新晶型化合物及制剂
摘要:本发明公开了一种头孢硫脒新晶型化合物及其结晶制备方法,所述头孢硫脒新晶型化合物采用粒子过程晶体产品分子组装与形态优化技术制备而成.本新晶型化合物具有纯度高,杂质含量低,流动性好,稳定性好的特点.同时,本发明还公开了一种采用上述头孢硫脒制备的制剂-注射用头孢硫脒.

专利信息

专利号:US-10053531-B2
优先权日:2012-11-20
标 题 :Molecularly imprinted polymer nanoparticles compatible with biological samples and preparation method thereof
发明人：ZHANG HUIQI; MA YUE; ZHANG YING; PAN GUOQING
权利人:UNIV NANKAI
摘要:This invention provides molecularly imprinted polymer nanoparticles compatible with biological samples, and in particular pure biological samples and a preparation method thereof. Said molecularly imprinted polymer nanoparticles have a crosslinking degree exceeding 50%, a particle diameter of 10 to 500 nm, hydrophilic polymer brushes on its surfaces and can be prepared by introducing appropriate hydrophilic macromolecular chain transfer agents into reversible addition-fragmentation chain transfer (RAFT) precipitation polymerization systems through the one-pot synthesis. The preparation method is simple, features a broad range of application and yields a pure product. The obtained hydrophilic molecularly imprinted polymer nanoparticles have prospects for a wide range of application in biological sample analysis, medical clinical immune analysis, food and environmental monitoring, biomimetic sensors, etc.

专利号:CN-111100144-A
优先权日:2019-12-30
标 题:A kind of synthesis technology of cefathiamidine

专利号:CN-101704827-B
优先权日:2009-08-18
标 题 :Synthesis method of cefathiamidine compound