CAS: 53562-86-0; (S)-Methyl 3-Hydroxybutanoate

相似化合物

1487-49-6 3976-69-0 6168-83-8

上下游产品

CAS号105-45-3 乙酰乙酸甲酯 | CAS号1185248-82-1 (S)-methyl 3-(4... | CAS号67-56-1 甲醇 | CAS号201230-82-2 carbon monoxide | CAS号16088-62-3 S-环氧丙烷 | CAS号133268-19-6 methyl (2R,3S)-... | CAS号186581-53-3 重氮甲烷 | CAS号6168-83-8 (s)-3-羟基丁酸 | CAS号1201813-85-5 methyl-3-(4,4,5... | CAS号6168-83-8 (s)-3-羟基丁酸 | CAS号67-56-1 甲醇 | CAS号82596-30-3 脱水二氢青蒿素 | CAS号71963-77-4 蒿甲醚 | CAS号119946-74-6 (S)-methyl 3-((... | CAS号127604-16-4 (S)-3-羟基正丁酸钠 | CAS号3461-39-0 methyl-3-phenyl... | CAS号24621-61-2 (S)-(+)-1,3-丁二醇 | CAS号112424-25-6 methyl (3S)-3-(...

乙酰乙酸甲酯置于1,4-Dihydronicotinamide Adenine Dinucleotide,(S)-Alcohol Dehydrogenase From Rhodococcus Erythropolis体系中,用 Phosphate Buffer 作为反应溶剂,化学反应生成 (S)-3-羟基丁酸甲酯
参考文献:在原位辅酶再循环与甲酸脱氢酶作用下,用(S)-醇脱氢酶在双相介质中制备酮的不对称还原
标题:在原位辅酶再循环与甲酸脱氢酶作用下,用(S)-醇脱氢酶在双相介质中制备酮的不对称还原
摘要:描述了来自红球红球菌的新型重组(S)-醇脱氢酶的底物范围.另外,已经开发了用于原位辅因子再生的酮的不对称生物催化还原的酶相容性两相反应介质.因此,可以在较高底物浓度10-200 Mm的条件下,在红景天红球菌醇脱氢酶和博伊假丝酵母的甲酸脱氢酶存在下,降低水溶性差的酮.反应生成的(S)醇具有中等至非常好的转化率,并且具有高达> 99%的ee.
DOI:10.1016/j.Tet.2003.11.066

专利信息

专利号:US-5145957-A
优先权日:1988-03-18
标 题:Stereoselective synthesis of a chiral cis 3-beta hydrogen (3R) 4-aroyloxy azetidinone
发明人：TSCHAEN DAVID M; LYNCH JOSEPH E; LASWELL WILLIAM L; VOLANTE RALPH P; SHINKAI ICHIRO
权利人:MERCK & CO INC
摘要:A process is described for the stereocontrolled synthesis of (3R,4R)-3-[(1R)-1-hydroxyethyl]-4-benzoyloxyazetidin-2-ones and their derivatives by cycloaddition involving an imine and a ketone, generated from 3(S)-hydroxybutyrate which are useful intermediates in the synthesis of carbapenem antibiotics.

专利号:EP-0333268-A1
优先权日:1988-03-18
标题:Process for synthesis of a chiral 3-beta hydrogen (3R) 4-aroyloxy azetidinone
发明人：TSCHAEN DAVID M; LYNCH JOSEPH E; LASWELL WILLIAM L; VOLANTE RALPH P; SHINKAI ICHIRO
权利人:MERCK & CO INC
摘要:A process is described for the stereo-­controlled synthesis of (3R,4R)-3-[(1R)-1-hydroxy­ethyl]-4-benzoyloxyazetidin-2-ones and their derivatives which are useful intermediates in the synthesis of carbapenem antibiotics.

专利号:US-12037317-B2
优先权日:2018-01-25
标 题:Synthesis of 3-hydroxybutyryl 3-hydroxybutyrate and related compounds
发明人：ULRICH SCOTT MICHAEL
权利人:BUCK INST RES AGING
摘要:In various embodiments methods of preparing hydroxybutyryl 3-hydroxybutyrate and related compounds are provided along with methods of use thereof.

专利号:US-6271195-B1
优先权日:1992-06-30
标题:Aminimide-containing molecules and materials as molecular recognition agents
发明人：HOGAN JOSEPH C JR
权利人:ARQULE INC
摘要:The design and synthesis of novel aminimide-based molecular modules and the use of the modules in the construction of new molecules and fabricated materials is disclosed. The new molecules and fabricated materials are molecular recognition agents useful in the design and synthesis of drugs, and have applications in separations and materials science.

专利号:US-2011263569-A1
优先权日:2007-08-22
标 题 :Ryanodine channel binders and uses thereof
发明人：COREY ELIAS JAMES
权利人:HARVARD COLLEGE
摘要:Increasing the affinity of calstabin-2 for the cardiac calcium channel RyR2 and thereby stabilizing the channel in the closed state has recently been identified as novel mechanism for treating heart failure, particularly ventricular arrhythmias. JTV-519, a 1,4-benzothiazepine derivative, has been shown to stabilize the calstabin2/RyR2 complex. Novel derivatives of JTV-519 that may be useful in treatment or prevention of heart failure, atrial fibrillation, or exercise-induced cardiac arrhythmias are provided. Synthetic methodology and intermediates in the synthesis of the inventive JTV-519 derivatives are also described.

专利号:US-6872747-B2
优先权日:2001-05-09
标题:Decalactones, method for making, and pharmaceuticals there from
发明人：BRINGMANN GERHARD; PROKOSCH PETER; EDRADA RU ANGELIE; HEUBES MARKUS; SUDARSONO; GUNTER ECKHARD
权利人:BIOTECMARIN GMBH
摘要:A novel class of decalactones with the general formula (I) and their stereoisomers is disclosed. A method for the synthesis of the decalactones of general formula (I) and the use of the decalactones in pharmaceutical compositions is also described.