CAS: 120153-08-4; 4-Borono-2-Fluorobenzoic Acid

该化合物是一种碳酸衍生物,其成分为碳酸以及苯环上的氟替代物,这种化合物在铃木-宫浦交叉组合反应中特别宝贵,因为碳酸组是关键的联结伙伴,而碳酸组则具有额外的功能化潜力. 以电子提炼的氟化物替代元素可增强反应性和稳定性,使其在制药和材料科学应用中有用. 其双重功能允许进一步衍生,使复杂分子能够合成. 化合物通常在惰性条件下处理,因为碳酸对蛋白质的敏感度.

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CAS号867256-77-7 4-羧基-3-氟苯基硼酸频哪醇酯 | CAS号1313712-87-6 4-氯羰基-3-氟苯硼酸 | CAS号1261929-07-0 3,3-二氟-[1,1-联苯]...

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    专利号:US-12037430-B2
    优先权日:2018-10-17
    标 题:Target substance polymer replica substrate, method for producing same, and method for producing substrate sensor
    发明人:TAKEUCHI TOSHIFUMI; SUNAYAMA HIROBUMI; TAKANO ERI
    权利人:UNIV KOBE NAT UNIV CORP; MURATA MANUFACTURING CO
    摘要:The present invention provides a polymer replica of a target molecule, the polymer replica being capable of accurately inheriting surface information possessed by the target molecule in a molecular imprinting technique. A polymer replica of a target substance, the target substance having multiple types of binding groups including at least a binding group BG 1 and a binding group BG 2 on the surface, wherein: the polymer replica is configured from a second molecularly imprinted polymer having, as a template, a first molecularly imprinted polymer having the target substance as a template; the polymer replica has on the surface thereof at least a binding group bg 1 at a position corresponding to the position of binding group BG 1 and a binding group bg 2 at a position corresponding to the position of the binding group BG 2 on the surface of the target substance; and the polymer replica of the target substance can be used as a template during synthesis of a molecularly imprinted polymer having a specific recognition site for the target substance because the polymer replica accurately inherits the surface information possessed by the target molecule.

    专利号:US-10995078-B2
    优先权日:2013-03-13
    标 题:Compounds and compositions for inhibition of FASN
    发明人:BAIR KENNETH W; LANCIA JR DAVID R; LI HONGBIN; LOCH JAMES; LU WEI; MARTIN MATTHEW W; MILLAN DAVID S; SCHILLER SHAWN E R; TEBBE MARK J
    权利人:FORMA THERAPEUTICS INC
    摘要:The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:

    专利号:US-12227528-B2
    优先权日:2017-11-09
    标 题:Glucose-sensitive albumin-binding derivatives
    发明人:KRUSE THOMAS; KOFOD-HANSEN MIKAEL; MUENZEL MARTIN WERNER BORCHSENIUS; THOEGERSEN HENNING; SAUERBERG PER; EWALD JAKOB; BEHRENS CARSTEN; HOEG-JENSEN THOMAS; BALSANEK VOJTECH; DROBNAKOVA ZUZANA; DROZ LADISLAV; HAVRANEK MIROSLAV; KOTEK VLADISLAV; STENGL MILAN; SNAJDR IVAN; DRUSANOVA HANA
    权利人:NOVO NORDISK AS
    摘要:This invention relates to glucose-sensitive albumin-binding diboron conjugates. More particularly the invention provides novel diboron compounds, and in particular diboronate or diboroxole compounds, useful as intermediate compounds for the synthesis of diboron conjugates.

    专利号:SU-1766922-A1
    优先权日:1986-12-17
    标题:2-(4-carboxy-3-halogenphenyl)-5-alkyl-1,3,2-dioxaborinanes as semiproducts for synthesis of liquid-crystalline derivatives of halogen-pnenyl-5-alkyl-1,3,2-dioxaborinanes
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    合成参考文献


    参考文献:10.1007/s12633-023-02662-6
    摘要:Hady MA. Recent Advances Ultra-Porous Drug Nano-Carriers: Synthesis and Targeting Approaches. Silicon. 2023 Sep 23;16(1):345–66. doi: 10.1007/s12633-023-02662-6.
    参考文献:10.1038/s41428-024-01000-w
    摘要:Nakamura K, Michida S, Naito M, Chung U, Katashima T. Relationship between the heterogeneity in particle dynamics and network topology in transient networks via a microrheological study. Polym J. 2024 Dec 09;57(4):427–34. doi: 10.1038/s41428-024-01000-w.
    参考文献:10.1007/s10853-025-10993-5
    摘要:Sheng X, He X, Zhang S, Yao X, Wang H, Yuan L. Promoting gene transfection by ribonucleotide-responsive silicon nanowire arrays. J Mater Sci. 2025 Jun;60(22):9313–26. doi: 10.1007/s10853-025-10993-5.
    参考文献:10.1007/s10847-025-01309-w
    摘要:Ishiki H, Taharabaru T, Arase H, Matsumoto Y, Onodera R, Motoyama K, Higashi T. Preparation of targeting materials for a boron-containing polyrotaxane in boron neutron capture therapy. J Incl Phenom Macrocycl Chem. 2025 Jun 27;105(9-10):569–77. doi: 10.1007/s10847-025-01309-w.
    参考文献:10.1038/s41428-025-01097-7
    摘要:Tanaka S, Fujita K, Yamamoto Y, Zulkiflie FAM, Suzuki T, Naito M, Chung U, Katashima T. Release mechanism of micrometer-scale particles from transient networks with well-controlled structures. Polym J. 2025 Aug 21;57(12):1383–90. doi: 10.1038/s41428-025-01097-7.
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