专利号:US-2025042860-A1 优先权日:2022-04-22 标题:Process for Chemical Synthesis of Ergothioneine and Methods of Use 发明人:ZHU YONGXIAO; YU DONGDONG; ZHU YING; ZHU XI; LIAO KYLIN 权利人:NANJING NUTRABUILDING BIO TECH CO LTD 摘要:The present invention provides a process for chemical synthesis of different optical forms of ergothioneine (e.g., L-form or D-form or any mixture thereof). Another aspect of the invention relates to a composition comprising a non-racemic mixture of L-ergothioneine and D-ergothioneine.
专利号:US-8618281-B2 优先权日:2006-01-03 标 题 :Geometric synthesis of porphyrin rods 发明人:LINDSEY JONATHAN S; YU LIANHE; THAMYONGKIT PATCHANITA; BHISE ANIL D 权利人:LINDSEY JONATHAN S; YU LIANHE; THAMYONGKIT PATCHANITA; BHISE ANIL D; UNIV NORTH CAROLINA STATE 摘要:A method of making a compound of Formula I′ n ncomprises reacting a compound of the formula DLCHO, with a compound of the formulan n nto produce the compound of Formula I′. Methods of using the compounds are also described, particularly as intermediates for the synthesis of porphyrin rods, which porphyrin rods are in turn useful for (among other things) the production of molecular memory devices.
专利号:US-6159673-A 优先权日:1996-07-17 标 题:Oxonol compound, light-sensitive material and process for the synthesis of oxonol compound 发明人:NISHIGAKI JUNJI; DEGUCHI YASUAKI 权利人:FUJI PHOTO FILM CO LTD 摘要:An oxonol compound is represented by the following formula (I): in which Z is an atomic group that forms a cyclic amide ring; each of W1 and W2 independently is an atomic group that forms an acidic nucleus ring; and M is a cation. Other oxonol compounds, a light-sensitive material containing an oxonol compound and a process for the synthesis of an oxonol compound are also disclosed.
专利号:US-4315857-A 优先权日:1979-07-20 标题 :Process for the synthesis of azobenzene compounds having a cyano group in one or both of the ortho positions of the diazo component radical 发明人:BUECHELER PAUL 权利人:SANDOZ LTD 摘要:A process for the synthesis of an azobenzene compound having a cyano group in one or both of the ortho positions of the diazo component radical comprising reacting the corresponding azobenzene compound having a chloro, bromo or iodo substituent in one or both of the ortho positions of the diazo component radical with a copper thiocyanate or copper thiocyanate-forming mixture of salts in the presence of an oxidizing agent (e.g., oxygen and sodium perborate), whereby the or at least one of the chloro, bromo and iodo substituents is replaced by a cyano group.
专利号:US-6080860-A 优先权日:1992-08-31 标 题:Methods of making ureas and guanidines including, terazosin, prazosin, doxazosin, tiodazosin, trimazosin, quinazosin and bunazosin (exemplary of 2-substituted quinazoline compounds), and meobentine, and bethanidine and intermediates therefor 发明人:KARIMIAN KHASHAYAR; MURTHY KESHAVA; HALL DARREN 权利人:BRANTFORD CHEMICALSS INC 摘要:Novel methods for the synthesis of substituted ureas and guanidines including Terazosin, Prazosin, Doxazosin, Tiodazosin, Trimazosin, Quinasin and Bunazosin (exemplary of 2-amino substituted Quinazolines), Meobentine and Bethanidine and novel intermediates suitable for use in such methods of synthesis are taught.
专利号:US-7038062-B2 优先权日:2004-07-01 标题:Synthesis of cyclic trithiocarbonates from epoxides 发明人:PARKER DANE KENTON 权利人:GOODYEAR TIRE & RUBBER 摘要:This invention provides a low cost technique for synthesizing cyclic trithiocarbonates by a simple one step process from epoxides that can be conducted under atmospheric pressure. This synthesis can be depicted as follows: n nwherein R represents a moiety selected from the group consisting of alkyl groups and aryl groups, wherein R′ represents a moiety selected from the group consisting of alkyl groups, aryl groups, and hydrogen atoms, and wherein R″ represents a moiety selected from the group consisting of alkyl groups, aryl groups, and hydrogen atoms, wherein the R moiety and the R′ moiety can be bonded together to form a cyclic structure, with the proviso that R″ represents a hydrogen atom if R′ represents an alkyl group or an aryl group. In this process carbon disulfide and a thiocyanate salt, such as potassium thiocyanate, are reacted with the epoxide in an ionic liquid, such as 1-butyl-3-methylimidazolium hexafluorophosphate ([Bmim] PF 6 ) in the presence of water to produce the cyclic trithiocarbonate.
[参考文献]: Andreas Elentner, Et Al. Skin Response To A Carcinogen Involves The Xenobiotic Receptor Pregnane X Receptor. Exp Dermatol. 2015 Nov;24(11):835-40. [参考文献]: Dongmei Shi, Et Al. Oral Administration Of Paeoniflorin Attenuates Allergic Contact Dermatitis By Inhibiting Dendritic Cell Migration And Th1 And Th17 Differentiation In A Mouse Model. Int Immunopharmacol. 2015 Apr;25(2):432-9. [参考文献]: Janani Swaminathan, Et Al. Effect Of Lyophilization On Liposomal Encapsulation Of Salmon Calcitonin. J Liposome Res. 2014 Dec;24(4):297-303. [参考文献]: Jie Xiao, Et Al. Kafirin Nanoparticle-Stabilized Pickering Emulsions As Oral Delivery Vehicles: Physicochemical Stability And In Vitro Digestion Profile. J Agric Food Chem. 2015 Dec 2;63(47):10263-70. [参考文献]: Jiradej Manosroi, Et Al. In Vitro Anti-Aging Activities Of Extracts From Leaves Of Ma Kiang (Cleistocalyx Nervosum Var. Paniala). Pharm Biol. 2015 Jun;53(6):862-9.
合成参考文献
摘要:Koutentis, P. A.; Ioannidou, H. A., Science of Synthesis Knowledge Updates, (2010) 1, 270. 摘要:Sainsbury, M., Science of Synthesis Knowledge Updates, (2010) 1, 222. 摘要:Koutentis, P. A.; Ioannidou, H. A., Science of Synthesis Knowledge Updates, (2010) 1, 346. 摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2010) 2, 236. 摘要:Shimada, K., Science of Synthesis Knowledge Updates, (2010) 1, 425.