CAS: 2086-83-1; 9,10-Dimethoxy-5,6-Dihydro-[1,3]Dioxolo[4,5-G]Isoquinolino[3,2-A]Isoquinolin-7-Ium

上下游产品

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Rac-(4Br,14Br)-3,4-Dimethoxy-8,9-Dihydro-6H-[1,3]Dioxolo[4,5-G]Indeno[2',1':4,5]Oxazolo[4,3-A]Isoquinolin-15(4Bh)-One置于sodium Cyanoborohydride体系中,用 甲醇 用作溶剂,以96%的收率获得小檗碱
参考文献:Hanaoka,Miyoji; Ashimori,Atsuyuki; Yasuda,Shingo,Heterocycles,1984,Vol. 22,# 10,P. 2263-2264
标题:Hanaoka,Miyoji; Ashimori,Atsuyuki; Yasuda,Shingo,Heterocycles,1984,Vol. 22,# 10,P. 2263-2264

专利信息

专利号:US-9315483-B2
优先权日:2007-09-13
标题 :Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof
发明人：JONES ANDREW D; ZELLE ROBERT E; SILVERMAN I ROBERT
权利人:CONCERT PHARMACEUTICALS INC
摘要:The present invention provides a convenient and efficient process for the synthesis of d 2 -benzo[d][1,3]dioxoles.

专利号:US-9856251-B2
优先权日:2008-09-03
标题:Substituted berbines and processes for their synthesis
发明人：WANG PETER X; MOSER FRANK W; CANTRELL GARY L; GROTE CHRISTOPHER W
权利人:MALLINCKRODT LLC
摘要:The present invention provides processes for the synthesis of substituted berbine compounds. Also provided are intermediates used in the synthesis of substituted berbine compounds.

专利号:US-9181237-B2
优先权日:2013-10-04
标 题 :Substituted berbines and their synthesis
发明人：GROTE CHRISTOPHER W
权利人:MALLINCKRODT LLC
摘要:The present invention provides substituted berbines, processes for the synthesis of substituted berbine compounds, as well as intermediates used in the synthesis of substituted berbine compounds. Also provided are methods for using the substituted berbines to inhibit cancer cell growth.

专利号:US-2008311580-A1
优先权日:2004-03-09
标 题:Novel genes encoding proteins involved in proanthocyanidin synthesis
发明人：ABRAHAMS SHARON; ASHTON ANTHONY RICHARD; TANNER GREGORY JOHN; LARKIN PHILIP JOHN
权利人:COMMW SCIENT IND RES ORG
摘要:This inventions provides an isolated protein or polypeptide having activity in the synthesis of proanthocyanidin (PA) polymer from epicatechin or catechin in plants, and which is not naturally regulated by the TT2 or TT8 regulators, or a fragment comprising at least about 10 contiguous amino acids derived from said protein or polypeptide, particularly TDS1, TDS2, TDS3, TDS4, TDS5, or TDS6 protein, or fragment thereof. n Also provided are nucleic acid encoding such proteins or polypeptides; plant cells and plants containing and expressing such nucleic acids; antibodies that bind to such proteins or polypeptides; and related methods.

专利号:US-9969686-B2
优先权日:2014-08-05
标 题 :Synthesis of diindolylmethanes and indolo[3,2-b]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them
发明人：TANG WEIPING; LI XIAOXUN; SHU DONGXU; WINSTON-MCPHERSON GABRIELLE N
权利人:WISCONSIN ALUMNI RES FOUND
摘要:Described is a method to make diindolylmethanes and indolyl/pyrrolylmethanes, The method includes the steps of contacting an ether comprising an arylpropargyl moiety and an amine-protected, substituted or unsubstituted aniline moiety with a substituted or unsubstituted indol or a substituted or unsubstituted pyrrole, in the presence of a metal-containing catalyst, for a time and at a temperature to cause an annulation/arylation cascade reaction that yields a diindolylmethane or a indolyl/pyrrolylmethane. The resulting compounds are effective to modulate activity of arylhydrocarbon receptors, to inhibit activity of PCSK9, and to stimulate secretion of glucagon-like peptide 1 in mammals.

专利号:US-7915276-B2
优先权日:2006-02-14
标题 :Berberrubine derivatives having antifungal activities
发明人：KIM SUNG UK; PARK KI DUK; MOON JAE SUN; KANG TAE HOON; KIM YOUNG KOOK
权利人:KOREA RES INST OF BIOSCIENCE
摘要:The present invention relates to a berberrubine derivative having superior antifungal activity, more particularly to a berberrubine derivative having activity against chitin synthase, which participates in the synthesis of chitin and is essential in the growth of fungi, and having a potent antifungal activity against human pathogenic fungi.