CAS: 2616-64-0; Uridine Diphosphate Glucuronic Acid

相似化合物

91183-98-1 50722-58-2 15839-78-8

上下游产品

Uridine Diphospho-α-D-Gluco-Hexodialdose 31932-92-0
尿苷(5')二氢二磷酰(1)-Alpha-D-葡萄糖 Udp-Glucose 133-89-1
尿苷 5’-二二氧磷基半乳糖二钠盐 Uridine 5'-Diphospho-D-Galactose 2956-16-3
尿苷-5’-二磷酸 Udp 58-98-0
尿苷-5'-三磷酸 Utp 63-39-8
尿苷5-单磷酸 5'-Uridylic Acid 58-97-9
Uridine 5′-Phosphoramidate 15483-88-2
5'-胞苷酸 Cytidine Monophosphate 63-37-6 α-D-Glucopyranuronic Acid 1-Phosphate 13168-11-1

尿苷5-单磷酸置于无机焦磷酸酶,Udp-Glucose Dehydrogenase,Uridine-5'-Diphosphoglucose Pyrophosphorylase,Sodium Perchlorate,β-烟酰胺腺嘌呤二核苷酸,三丁基焦磷酸铵,丙酮酸体系中,用 甲醇,乙醇,乙腈 用作溶剂,化学反应 49.0H,反应生成6-[[[5-(2,4-二氧代嘧啶-1-基)-3,4-二羟基四氢呋喃-2-基]甲氧基-羟基磷酰]氧基-羟基磷酰]氧基-3,4,5-三羟基四氢吡喃-2-羧酸
参考文献:Convenient Syntheses Of Cytidine 5'-Triphosphate,Guanosine 5'-Triphosphate,And Uridine 5'-Triphosphate And Their Use In The Preparation Of Udp-Glucose,Udp-Glucuronic Acid,And Gdp-Mannose
标题:Convenient Syntheses Of Cytidine 5'-Triphosphate,Guanosine 5'-Triphosphate,And Uridine 5'-Triphosphate And Their Use In The Preparation Of Udp-Glucose,Udp-Glucuronic Acid,And Gdp-Mannose
摘要:
Doi:10.1021/jo00293A030

专利信息

专利号:US-5824472-A
优先权日:1986-03-24
标 题 :Process for the synthesis of sugar nucleotides using recombinant-DNA methods
发明人：BETLACH MICHAEL R; DOHERTY DANIEL H; VANDERSLICE REBECCA W
权利人:MONSANTO CO
摘要:A recombinant-DNA mediated method for the synthesis of sugar nucleotides is disclosed. This method utilizes portable DNA sequences capable of directing the microbial synthesis of various enzymes that catalyze the synthesis of sugar nucleotides, including UDP-glucose, UDP-glucuronic acid and GDP-mannose. The sugar moieties of these sugar nucleotides may subsequently be incorporated into industrially-useful polysaccharides such as xanthan gum. It has been found that vectors containing the portable DNA sequences described herein are capable both of causing sugar nucleotide production in microorganisms previously incapable of such synthesis and of causing increased sugar nucleotide production in organisms capable of synthesizing small quantities of these compounds. In particular, plasmids pAS7, pAS9 and pTS13 are disclosed. These plasmids are capable of directing sugar nucleotide synthesis in various hosts, including Xanthomonas sp. such as X. campestris and other organisms such as E. coli and various Pseudomonas sp.

专利号:US-6156547-A
优先权日:1990-04-16
标 题:Apparatus for the synthesis of saccharide compositions
发明人：ROTH STEPHEN
权利人:NEOSE PHARM INC
摘要:This invention relates to an apparatus containing specific binary combinations of glycosyltransferases, for the synthesis of specific saccharide compositions such as, for example, oligosaccharides, polysaccharides, glycolipids, and glycopeptides.

专利号:WO-9720061-A1
优先权日:1995-11-30
标题:Synthesis of hyaluronic acid
发明人：WONG CHI-HUEY; DELUCA CLAUDIO
权利人:SCRIPPS RESEARCH INST; WONG CHI HUEY; DELUCA CLAUDIO
摘要:A preparative enzymatic synthesis of hyaluronic acid (HA) from UDP-N-acetyl-D-glucosamine (UDP-GlcNAc) and UDP-glucuronic acid (UDP-GlcA) catalyzed by hyaluronic acid synthase is coupled with regeneration of the sugar nucleotides. Polymerizing UDP-GlcA and UDP-GlcNAc to form hyaluronic acid results in the formation of released UDP. The released UDP is, in turn, employed in the regeneration of UDP-GlcA and UDP-GlcNAc. Use of the released UDP for regenerating UDP-GlcA and UDP-GlcNAc prevents a build-up of these compounds and prevents or reduces feed back inhibition of the hyaluronic acid synthase reaction that would otherwise be caused by such build-up. Accordingly, the product yield is enhanced by the recycling of these compounds.

专利号:WO-2024165611-A1
优先权日:2023-02-07
标题:Production of a disaccharide and/or milk oligosaccharide by a cell with reduced synthesis of udp-glcnac
发明人：BEAUPREZ JOERI; DECOENE THOMAS; VERCAUTEREN ANNELIES
权利人:INBIOSE NV
摘要:The present invention is in the technical field of synthetic biology, metabolic engineering and cell cultivation. The invention provides a cell for production of a disaccharide and/or an oligosaccharide like a milk oligosaccharide wherein synthesis of UDP-N-acetylglucosamine in said cell is rendered less functional. The invention further provides use of said cell in a cultivation or incubation. The invention also describes methods for the production of a disaccharide and/or an oligosaccharide like a milk oligosaccharide using said cell as well as the purification of said disaccharide and/or oligosaccharide like a milk oligosaccharide.

专利号:WO-2024165524-A1
优先权日:2023-02-06
标 题:Production of a saccharide by a cell with reduced synthesis of lactobionic acid
发明人：BEAUPREZ JOERI; DECOENE THOMAS; VERCAUTEREN ANNELIES
权利人:INBIOSE NV
摘要:The present invention is in the technical field of synthetic biology, metabolic engineering and cell cultivation. The invention provides a cell for production of a saccharide wherein synthesis of lactobionic acid in said cell is rendered less functional or is knocked out. The invention further provides use of said cell in a cultivation or incubation. The invention also describes methods for the production of a saccharide using said cell as well as the purification of said saccharide.

专利号:US-2002132320-A1
优先权日:2001-01-10
标题:Glycoconjugate synthesis using a pathway-engineered organism
发明人：WANG PENG GEORGE; CHEN XI; LIU ZIYE; ZHANG WEI
摘要:This invention relates to methods and compositions for the production of glycoconjugates. In particular, organisms are provided with at least one heterologous gene encoding an enzyme for regenerating a sugar nucleotide along with at least one glycosyltransterase. Such organisms are useful for the large-scale synthesis of glycoconjugates.