CAS: 403-16-7; 3-Chloro-4-Fluorobenzoic Acid

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CAS号65055-17-6 3-氯-4-氟苯甲酰氯 | CAS号456-22-4 对氟苯甲酸 | CAS号60811-21-4 4-溴-2-氯-1-氟苯 | CAS号590-29-4 甲酸钾 | CAS号348-51-6 2-氯氟苯 | CAS号2923-66-2 3'-氯-4'-氟苯乙酮 | CAS号348-51-6 2-氯氟苯 | CAS号36556-52-2 2,3-二氯-4-氟 | CAS号65055-17-6 3-氯-4-氟苯甲酰氯 | CAS号137521-81-4 3-氯-4-氟苯甲酸乙酯 | CAS号234082-35-0 3-氯-4-氟苯甲酸甲酯 | CAS号154257-76-8 2,3-二氯-4-氟苯甲酸 | CAS号161446-90-8 3-氯-4-氟苯甲醇 | CAS号36667-05-7 2,3,4-tribromob... | CAS号863454-79-9 1-[(3-氯-4-氟苯基)羰...

对氟苯甲酸置于三氟甲磺酸,三氯异氰尿酸体系中,化学反应 24.0H,以65%的收率获得产物3-氯-4-氟苯甲酸
参考文献:具有吸电子取代基的芳烃催化亲电卤化
标题:具有吸电子取代基的芳烃催化亲电卤化
摘要:芳烃的亲电卤化可能是制备芳基卤化物的最简单方法,芳基卤化物是农用化学品,材料和药物中的重要结构基序.然而,芳烃的亲核性被吸电子取代基削弱,其亲电子卤化反应通常需要苛刻的条件,导致底物范围和应用受到限制.因此,在温和条件下卤化含有吸电子基团(ewgs)和复杂生物活性化合物的芳烃一直是一个长期的挑战.在此,我们描述了在温和条件下具有吸电子取代基的芳烃的 Brønsted 酸催化卤化,为芳基卤化物提供了一种有效的方案.布朗斯台德酸与质子溶剂 1,1,1,3,3 的氢键,
DOI:10.1021/jacs.2C06440

专利信息

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:CN-116813475-A
优先权日:2022-06-29
标题 :A kind of halogenation synthesis method of aromatic ring compounds