CAS: 53661-18-0; 4-Ethylphenylhydrazine Hydrochloride

上下游产品

4-aminoethylbenzene 1-bromo-4-ethylbenzene 4-ethyl-1-iodobenzene N-(4-Ethyl-phenyl)-N'-[1-phenyl-1-(5-phenyl-[1,2,4]oxadiazol-3-yl)-meth-(Z)-ylidene]-hydrazine N-(4-Ethyl-phenyl)-N'-[1-phenyl-1-(5-phenyl-[1,2,4]oxadiazol-3-yl)-meth-(E)-ylidene]-hydrazine 2-(5-ethyl-1H-indol-3-yl)ethylamine

1-乙基-4-碘苯置于potassium Phosphate,Copper(L) Iodide,N,N'-二(2,6-二甲基苯基)草酰胺,十六烷基三甲基溴化铵,一水合肼,盐酸体系中,用 水 作为反应溶剂,化学反应 0.25H,以72%的收率获得产物4-乙基苯肼盐酸盐
参考文献:Cui / Bmpo催化卤代芳烃与水合肼的交叉偶联合成芳族肼
标题:Cui / Bmpo催化卤代芳烃与水合肼的交叉偶联合成芳族肼
摘要:的n,N-双(2,6-二甲基苯基)草酰胺,发现作为一个强大的配体对cu催化的与水合肼芳基卤化物的交叉耦合,从而导致的各种芳基肼的形成在80 ö用c在k 3 Po 4和4 Mol%的十六烷基三甲基溴化铵的帮助下,从芳基溴化物和芳基碘化物中加入水.在大多数情况下,观测到非常好至极好的产量.
DOI:10.1002/cjoc.201800326

专利信息

专利号:US-11040938-B2
优先权日:2016-07-27
标 题 :Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts
发明人：MA BING; PAN SHUAI
权利人:SHANGHAI HYBRID—CHEM TECH; SHANGHAI HYBRID CHEM TECH
摘要:The present invention provided a continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts. Diazotization, reduction, acidic hydrolysis and salifying with acids are innovatively integrated together. Using acidic liquids of aniline or substituted aniline, diazotization reagents, reductants and acids as raw materials, phenylhydrazine derivative salts is obtained through the synthesis process, which is a three-step continuous tandem reaction including diazotization, reduction, acidic hydrolysis and salifying. The described synthesis process is a kind of integrated solutions, which is carried out in an integrated reactor. The feed inlets of the integrated reactor are continuously filled with raw materials. In the integrated reactor, diazotization, reduction, acidic hydrolysis and salifying are carried out continuously and orderly, and phenylhydrazine salts or substituted phenylhydrazine salts is obtained in the outlet of the integrated reactor without interruption. The total reaction time is no more than 20 min.

专利号:US-2019152896-A1
优先权日:2016-07-27
标题 :Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts

专利号:CN-107663161-B
优先权日:2016-07-27
标题:A kind of continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt

专利号:CN-107663161-A
优先权日:2016-07-27
标 题 :A kind of continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt