CAS: 1195-08-0; 2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Carbaldehyde

上下游产品

CAS号4433-40-3 5-羟甲基脲嘧啶 | CAS号23956-12-9 5-(2-羟基乙基)尿嘧啶 | CAS号66-22-8 尿嘧啶 | CAS号65-71-4 胸腺嘧啶 | CAS号4494-26-2 1-((2r,4s,5r)-4... | CAS号28100-77-8 5-thyminyl-5,6-... | CAS号69304-49-0 (E)-5-(2-溴乙烯基)-... | CAS号69304-47-8 溴夫定 | CAS号23945-44-0 脲嘧啶-5-羧酸 | CAS号77530-00-8 5-(2-bromoethyn... | CAS号42821-92-1 2,4-二羟基嘧啶-5-甲酸甲酯 | CAS号55520-60-0 (E)-5-ETHOXYCAR... | CAS号57412-59-6 (E)-5-CARBOXYVI... | CAS号61135-31-7 5-(2,2-dibromoe...

尿嘧啶置于盐酸,Sodium Hydroxide体系中,用 氯仿,水 用作溶剂,化学反应生成5-甲酰基尿嘧啶
参考文献:Pyrimidinedione,Pyrimidinetrione,Triazinedione And
标题:Pyrimidinedione,Pyrimidinetrione,Triazinedione And
摘要:化合物的化学式i:##str1##其中r.Sup.5是从式(A),(B),(C)和(D)中选择的基团:##str2##以及其药用可接受的盐和n-氧化物,是用于治疗涉及直接或间接阻塞下尿道的疾病,如良性前列腺增生的α1-肾上腺素受体拮抗剂.

专利信息

专利号:US-12421628-B2
优先权日:2018-07-23
标题:Massively parallel enzymatic synthesis of nucleic acid strands
发明人：HORGAN ADRIAN; GODRON XAVIER; YBERT THOMAS; NICOL ROBERT
权利人:DNA SCRIPT
摘要:The invention is directed to methods for massively parallel template-free enzymatic synthesis of a plurality of different polynucleotides of predetermined sequences. In one aspect, methods of the invention employ large scale arrays of reaction sites each associated with at least one working electrode for controlling deprotection and deblocking steps at predetermined user selected sites. In another aspect, the invention provides template-free enzymatic synthesis with proofreading, wherein completed polynucleotides at predetermined reaction sites are sequenced using a sequencing by synthesis technique, particularly employing electrochemically labile blocking groups.

专利号:US-2024052391-A1
优先权日:2020-10-29
标 题 :Enzymatic Synthesis of Polynucleotide Probes
发明人：GODRON XAVIER; NIYOMCHON SUPAPORN; CHAMPION ELISE
权利人:DNA SCRIPT
摘要:The present invention is directed to methods and kits for enzymatic synthesis of labeled polynucleotide probes using template-free DNA polymerases.

专利号:US-10266565-B2
优先权日:2011-04-12
标 题 :Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use
发明人：BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG-EUN
权利人:BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG EUN; THE US SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
摘要:Novel compounds are provided that bind to polo-like kinases through the polo-box domain. In certain embodiments, the novel compounds are PEGylated peptides. The PEGylated peptides in accordance with the invention demonstrate high PBD-binding affinity. In certain embodiments, the PEGylated peptides have also achieved activities in whole cell systems. The invention also provides compounds that bind polo-like kinases through the polo-box domain and possess reduced anionic charge. Further provided are methods of design and/or synthesis of the PEGylated peptides and methods of use thereof. The invention provides methods of use of the compounds and methods of synthesis of the compounds.

专利号:US-4567260-A
优先权日:1982-07-01
标题:Synthesis of 5-deazariboflavine
发明人：YONEDA FUMIO
权利人:TOYO JOZO KK
摘要:A new synthesis of 5-deazariboflavine is afforded by condensing N-D-ribityl-3,4-xylidine with a novel chemical intermediate, 6-chloro-5-formyluracil.

专利号:US-4849513-A
优先权日:1983-12-20
标 题 :Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups
发明人：SMITH LLOYD M; FUNG STEVEN; KAISER ROBERT J
权利人:CALIFORNIA INST OF TECHN
摘要:The invention consists of compounds and methods for the synthesis of oligonucleotides which contain one or more free aliphatic amino groups attached to the sugar moieties of the nucleoside subunits. The synthetic method is versatile and general, permitting amino groups to be selectively placed at any position on oligonucleotides of any composition or length which is attainable by current DNA synthetic methods. Fluorescent dyes or other detectable moieties may be covalently attached to the amino groups to yield the corresponding modified oligonucleotide.

专利号:US-5118802-A
优先权日:1983-12-20
标 题:DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside
发明人：SMITH LLOYD M; FUNG STEVEN; KAISER JR ROBERT J
权利人:CALIFORNIA INST OF TECHN
摘要:The invention consists of compounds and methods for the synthesis of oligonucleotides which contain one or more free aliphatic amino groups attached to the sugar moieties of the nucleoside subunits. The synthetic method is versatile and general, permitting amino groups to be selectively placed at any position on oligonucleotides of any composition or length which is attainable by current DNA synthetic methods. Fluorescent dyes or other detectable moieties may be covalently attached to the amino groups to yield the corresponding modified oligonucleotide.