CAS: 160347-90-0; (R)-1-(Tert-Butoxycarbonyl)-5-Oxopyrrolidine-2-Carboxylic Acid

相似化合物

160401-16-1 149-87-1 32159-21-0

上下游产品

L-glutamic acid 2-hydroxymethyl-5-oxopyrrolidine-1-carboxylic acid tert-butyl ester 4-nitrobenzyl L-1-tert-butoxycarbonylpyroglutamate benzyl (2S)-N-tert-butoxycarbonyl-5-oxoprolinatetert-butyl (S)-2-(((tert-butyldimethylsilyl)oxy)methyl)-5-oxopyrrolidin-1-carboxylate (S)-tert-butyl 2-(((tert-butyldimethylsilyl)oxy)methyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate tert-butyl (1S,6R)-3-formyl-6-hydroxycyclohex-3-enylcarbamate ethyl (4R,5S)-5-(tert-butoxycarbonylamino)-4-hydroxycyclohex-1-enecarboxylate

专利信息

专利号:US-8835466-B2
优先权日:2006-04-20
标 题 :Synthesis and uses of pyroglutamic acid derivatives
发明人：à LVAREZ BUILLA GÓMEZ JULIO; NOVELLA ROBISCO JOSÉ LUIS; MATà A MARTà N MA PAZ; SERNA PEREDA SONIA
权利人:à LVAREZ BUILLA GÓMEZ JULIO; NOVELLA ROBISCO JOSÉ LUIS; MATà A MARTà N MA PAZ; SERNA PEREDA SONIA; PRODIMED SA
摘要:Novel pyroglutamic acid derivatives (I), wherein R 1 is —OH, —ORa, wherein Ra is alkyl, cycloalkyl, alkenyl, cycloalkenyl, aryl, aralkyl or heterocyclyl; R 2 , R 3 and R 4 are independently H, a nitrogen protecting group which hydrolyzes under acidic conditions or phtalamide; X is a pharmaceutically acceptable anion; and Y is a N-containing group; either in the form of their isolated optically active stereoisomers or in the form of mixtures thereof, are useful compounds for enhancing an immuneresponse in a subject and/or for treating tumors, bacterial, fungal or viral infections, or autoimmune diseases.

专利号:US-2009163555-A1
优先权日:2006-04-20
标 题:Synthesis and uses of pyroglutamic acid derivatives

专利号:EP-2021334-B1
优先权日:2006-04-20
标 题:Synthesis and uses of pyroglutamic acid derivatives