CAS: 1620-77-5; 5-Methylpicolinonitrile

相似化合物

4434-13-3 4985-92-6 177359-60-3

上下游产品

3-picoline-N-oxide dimethyl sulfate 2-chloro-5-methylpyridine trimethylsilyl cyanide 5-methyl-N-[4-(methylthio)phenyl]-2-pyridinecarboximidamide 5-methylpyridine-2-thi°Carboxamide 5-(bromomethyl)pyridine-2-carbonitrile 5-(aminomethyl)pyridine-2-carbonitrile

2-羟基-5-甲基嘧啶置于五氯化磷,水,Sodium Sulfite,三氯氧磷体系中,化学反应生成2-氰基-5-甲基吡啶
参考文献:Suzuki,Pharmaceutical Bulletin,1957,Vol. 5,P. 13
标题:Suzuki,Pharmaceutical Bulletin,1957,Vol. 5,P. 13

专利信息

专利号:US-7745456-B2
优先权日:2000-11-06
标题 :Synthesis and antimicrobial activity of novel dicationic “reversed amidinesâ€?
发明人：BOYKIN DAVID W; TIDWELL RICHARD R; WILSON W DAVID; PERFECT JOHN R; STEPHENS CHAD E
权利人:UNIV NORTH CAROLINA; UNIV DUKE; UNIV GEORGIA STATE RES FOUND
摘要:The present invention relates to novel 2,5-bis{[alkyl (or aryl) imino] aminophenyl}furans and thiophenes of the general formula n nin which R 1 , R 2 , R 3 and R 4 are each independently selected from the group consisting of H, alkyl, alkoxy, halide, and alkylhalide groups; R 5 is H, alkyl or aryl; R 6 is H, alkyl, aryl, or NR 7 R 8 , in which R 7 and R 8 are each independently selected from the group consisting of H, alkyl and aryl; and X is O, S or NR 9 , in which R 9 is H or alkyl, and to the use of such compounds.

专利号:US-8952042-B2
优先权日:2009-08-19
标 题 :FXR (NR1H4) binding and activity modulating compounds
发明人：KREMOSER CLAUS; ABEL ULRICH; STEENECK CHRISTOPH; KINZEL OLAF
权利人:KREMOSER CLAUS; ABEL ULRICH; STEENECK CHRISTOPH; KINZEL OLAF; PHENEX PHARMACEUTICALS AG
摘要:The present invention relates to compounds of formula (1): n nwhere R, A, Q and Z are defined herein, or an enantiomer, diastereomer, tautomer, solvate, prodrug or pharmaceutical acceptable salt thereof. These compounds bind to the NR1H4 receptor (FXR) and act as agonists of the NR1H4 receptor (FXR). The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds, and to a process for the synthesis of said compounds.

专利号:SU-651837-A1
优先权日:1977-07-01
标 题 :Catalyst for synthesis of nitriles of 5-ethylpicolining and isocinchomeronic acids

专利号:US-2021284987-A1
优先权日:2017-05-27
标 题:Engineered polypeptides and their applications in the synthesis of beta-hydroxy-alpha-amino acids

专利号:US-2004235927-A1
优先权日:2000-11-06
标 题 :Synthesis and antimicrobial activity of novel dicationic 'reversed amidines'

专利号:US-7241795-B2
优先权日:2000-11-06
标题 :Synthesis and antimicrobial activity of novel dicationic “reversed amidinesâ€?