CAS: 2550-26-7; 4-Phenylbutan-2-One

上下游产品

CAS号3506-88-5 3-苄基-4-苯基-2-丁酮 | CAS号31984-10-8 1-溴-4-苯基丁-2-酮 | CAS号55985-68-7 3-溴-4-苯基-2-丁酮 | CAS号41162-19-0 2-氧代-4-苯丁基磷酸二甲酯 | CAS号1780-19-4 1.2.3.4-四氢-2-甲基喹啉 | CAS号4187-57-9 (S)-(+)-1-甲基-3-苯基丙胺 | CAS号937-52-0 (R)-α-甲基苯丙胺 | CAS号67-64-1 丙酮 | CAS号98-86-2 苯乙酮 | CAS号693-54-9 2-癸酮

二苯基羟基乙酸置于copper(Ll) Bromide,Lithium Tert-Butoxide体系中,用 四氢呋喃,正己烷 用作溶剂,化学反应 2.0H,以86%的收率获得苄基丙酮
参考文献:Oxidative Decarboxylation Of α-Amino And α-Hydroxy Acids Using Copper(II) Bromide-Lithium Tert-Butoxide
标题:Oxidative Decarboxylation Of α-Amino And α-Hydroxy Acids Using Copper(II) Bromide-Lithium Tert-Butoxide
摘要:α-单烷基α-氨基酸经铜(II)溴化物-叔丁醇锂处理后,以非常好产率氧化为相应的烷基腈.α,α-二取代的α-氨基酸和α-羟基酸的氧化也得到了相应的酮.
Doi:10.1055/s-1996-4267

专利信息

专利号:EP-4092127-A1
优先权日:2021-05-18
标题:Enzyme-catalytic method for the direct stereoselective synthesis of gamma-(acyloxy) carboxylic acids
发明人：PARVE JAAN; KUDRJASHOVA MARINA; GATHERGOOD NICHOLAS; PARVE OMAR
权利人:TALLINN UNIV OF TECHNOLOGY
摘要:The present invention is a method for the stereoselective straightforward synthesis of gamma-acyloxy carboxylic acids of novel structure starting from racemic gamma-hydroxy carboxylic acid salts that are obtained by alkaline hydrolysis of the racemic gamma-lactones. The salt is acylated by enzyme catalysis in an organic solvent containing an acyl donor and an immobilised lipase, on stirring at room temperature (ca 20 °C) until reaching the conversion rate required. After that, the reaction mixture is acidified and extracted and the product treated with catalytic amount of para-toluenesulfonic acid in toluene during the time required for the relactonisation of the unreacted salt enantiomer. Thereafter, the target gamma-acyloxy carboxylic acid formed from one enantiomer of the starting compound and relactonised gamma-lactone formed from the other, unreacted enantiomer of the starting compound are isolated using a routine separation method, such as distillation, extraction with NaHCO3 water solution followed by acidification or column chromatography.

专利号:WO-2015120485-A1
优先权日:2014-02-10
标 题:Water, bubble collapse and syngas species in the synthesis of graphene and its derivatives
发明人：SHANKMAN RICHARD S
权利人:PEERLESS WORLDWIDE LLC
摘要:Hydrodynamic cavitation-inducing inertial, non-inertial, and combination reactors are employed in the hydrothermal synthesis of graphene and its derivatives, both in solution and vapor. Various hydrodynamic cavitation reactor embodiments are revealed. Water is used to both nucleate and 'self-heal' graphene sheet growth in solution and vapor. Various methods of combustion, hydrothermal and dehydration synthesis of graphene and its derivatives are revealed. Additionally, water and ice are used as a substrate, both alone and in combination with other substrates, to grow and recover useful graphene and its derivatives.

专利号:US-10280189-B2
优先权日:2012-07-17
标题:Method for the synthesis of aminoalkylenephosphonic acid
发明人：BURCK SEBASTIAN; LECLERCQ CEDRIC NICOLAS; NOTTE PATRICK
权利人:MONSANTO TECHNOLOGY LLC
摘要:A method for the synthesis of an aminoalkylenephosphonic acid or its phosphonate esters including the following steps: a) forming, in the presence of an aldehyde or ketone and an acid catalyst, a reaction mixture by mixing a compound having at least one HNR 1 R 2 moiety or a salt thereof, with a compound having one or more P—O—P anhydride moieties, the moieties having one P atom at the oxidation state (+III) and one P atom at the oxidation state (+III) or (+V), wherein the ratio of moles of aldehyde or ketone to N—H moieties is 1 or more and wherein the ratio of N—H moieties to P—O—P anhydride moieties is 0.3 or more, and b) recovering the resulting aminoalkylenephosphonic acid having compound or its phosphonate esters.

专利号:EP-1075534-B8
优先权日:1998-03-11
标 题 :Improvements in the enzymatic synthesis of chiral amines
发明人：WU WEI; BHATIA MOHIT B; LEWIS CRAIG M; LANG WEI; WANG ALICE; MATCHAM GEORGE W
权利人:CELGRO
摘要:2-Aminopropane is used as the amine donor in the stereoselective synthesis of a chiral amine from a ketone with a transaminase. In a typical embodiment, (S)-1-methoxy-2-aminopropane is prepared by bringing methoxyacetone into contact with a transaminase in the presence of 2-aminopropane as an amine donor until a substantial amount of methoxyacetone is converted to (S)-1-methoxy-2-aminopropane and 2-aminopropane is converted to acetone. In a second embodiment, L-alanine is prepared by bringing pyruvic acid into contact with a transaminase in the presence of 2-aminopropane as an amine donor.

专利号:US-5488131-A
优先权日:1994-03-23
标题:Synthesis of compounds with predetermined chirality
发明人：MYERS ANDREW G
权利人:CALIFORNIA INST OF TECHN
摘要:A method for synthesizing enantiomerically enriched chemical intermediates with predetermined chirality is described. The method comprises formation of a pseudoephedrine amide, followed by stereoselective alkylation at the alpha carbon. The chiral auxiliary can then be cleaved off, affording chiral end products useful for further transformations. The enantiomeric enrichment of the chiral end products may exceed 98%, and the chiral auxiliary can be recovered. Novel amides of pseudoephedrine used in this method are also disclosed.

专利号:US-4567265-A
优先权日:1984-01-16
标题:Cyclopropanoid cyanoesters and method of making same
发明人：BABLER JAMES H
权利人:UNIV LOYOLA CHICAGO
摘要:Cyclopropanoid cyanoesters of the formula: where R' is -CH3 or -CH2CH3, and A is (a) -H, or (b) A, B represents an aliphatic group joined to a carbon atom on the cyclopropanoid ring, thereby forming a spiro group, A, B being selected from structures having the formula: (i) -(CH2)n-, wherein n=3, 4, or 5, and (ii) -(CH2)2-Y-(CH2)2-, wherein Y is NCH3, O, or S); and, when A is -H, B is selected from the group consisting of: +TR (CH3)2CHCH2. are disclosed. These compositions are useful in the synthesis of pyrethroids. A process for synthesis of cyclopropanoid cyanoesters by reacting 2-nitropropane with cyanoesters of the general formula: is also disclosed and claimed.