CAS: 622-96-8; 1-Ethyl-4-Methylbenzene

该化合物是一种芳香烃,其特点是乙基化合物和附于苯环的甲基化合物,具体地说,其配置为副形;该化合物在室内温度下无色可粉黄液,具有典型的芳香味;在水中略易溶,但易溶于乙醇和乙醇等有机溶剂.p-乙基甲苯与其他许多芳香化合物相比,其沸点相对较低,使其挥发性.其化学结构有助于其再活动,使其得以参与典型的亚芳化合物的各种化学反应,例如电子代用. p-乙二甲苯主要用作有机合成的中间体,还可能在染料,芳香和其他化学产品的生产中找到用途.安全考虑包括在通风良好的地区处理它,并使用适当的个人防护设备,因为若吸入或摄取,可能会有害.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

oxirane para-xylene diethyl sulfate 4-dichloroiodanyl-toluene p-tolyl-ethyl)-succinic acid(1-p-tolyl-ethyl)-succinic acid 1-sec-butyl-4-methylbenzene 4-ethyl-1-methyl-2-(1-methyl-cyclohexyl)-benzene p-tolyl-ethane1-(5-ethyl-2-methyl-phenyl)-1-p-tolyl-ethane

合成工艺路线路线简述

    1-甲基-4-[1-(4-甲基苯基)乙基]苯置于氢气,镍体系中,400.0 °C,1.96 Mpa 条件下,反应生成 4-乙基甲苯
    参考文献:Production Of Aromatic Hydrocarbons From Diarylalkanes
    标题:Production Of Aromatic Hydrocarbons From Diarylalkanes

    海关参考信息

    专利信息


    专利号:US-2003162992-A1
    优先权日:2001-12-14
    标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
    发明人:WATANABE KYOICHI A; DU JINFA
    摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

    专利号:US-5475177-A
    优先权日:1989-05-26
    标 题:Process for the synthesis of alkylated aromatic hydrocarbons
    发明人:GANHY JEAN-PIERRE
    权利人:SOLVAY INTEROX
    摘要:PCT No. PCT/EP92/02026 Sec. 371 Date May 19, 1994 Sec. 102(e) Date May 19, 1994 PCT Filed Sep. 2, 1992 PCT Pub. No. WO93/05001 PCT Pub. Date Mar. 18, 1993.Process for the synthesis of alkylated aromatic hydrocarbons containing a saturated alkyl chain comprising at least four carbon atoms, according to which an aromatic hydrocarbon substituted by a saturated short-chain alkyl group comprising one to three carbon atoms is reacted with an olefin in the presence of a catalyst which comprises at least one alkali metal or one alkali metal hydride impregnated on an alumina support and the catalyst is prepared in the reaction medium in the presence of the aromatic hydrocarbon containing a short alkyl chain by mixing anhydrous alumina with the alkali metal hydride or with the alkali metal, the ratio by weight of the alkali metal or of the alkali metal hydride to the alumina support being between 0.6 and 1.8. Use of the process for the synthesis of tert-amylbenzene by alkylation of cumene with ethylene.

    专利号:US-5288936-A
    优先权日:1989-05-26
    标题 :Process for the synthesis of alkylated aromatic hydrocarbons
    发明人:GANHY JEAN-PIERRE; JACOBS PIERRE; BAES MARLEEN; MARTENS JOHAN
    权利人:INTEROX SA
    摘要:PCT No. PCT/BE90/00022 Sec. 371 Date Jan. 24, 1992 Sec. 102(e) Date Jan. 24, 1992 PCT Filed May 25, 1990 PCT Pub. No. WO90/14323 PCT Pub. Date Nov. 29, 1990.Process for the synthesis of aromatic alkylated hydrocarbons with a saturated alkyl chain including at least four carbon atoms, according to which an aromatic hydrocarbon, replaced by an alkyl group with a short saturated chain comprising one to three carbon atoms, is made to react with an olefin in the presence of a catalyst made up of at least one alkaline metal or a alkaline metal hydride impregnated on an alumina support. The process is characterised by the fact that the catalyst is prepared in the reaction medium in the presence of the aromatic hydrocarbon with a short alkyl chain by mixing anhydrous alumina with the alkaline metal hydride or with the alkaline metal, and then the olefin is introduced in order to start the reaction.

    专利号:US-4565896-A
    优先权日:1984-10-22
    标 题 :Process for low pressure synthesis of ethylene glycol from synthesis gas
    发明人:KNIFTON JOHN F; DURANLEAU ROGER G
    权利人:TEXACO INC
    摘要:This invention relates to the manufacture of ethylene glcyol and more particularly to a low pressure process for making ethylene glycol comprising reacting synthesis gas, i.e. a mixture of carbon monoxide and hydrogen, plus formaldehyde in the presence of a homogeneous liquid catalyst containing an effective amount of cobalt-containing compound and a silicon or germanium-containing promoter and a solvent at a temperature of at least 50 DEG C. and a pressure of at least 500 psi wherein said ethylene glycol product separates as a separate liquid phase from the solvent.

    专利号:US-6245937-B1
    优先权日:1996-11-29
    标题 :Liquid phase parallel synthesis of chemical libraries
    发明人:CHENG SOAN; SAUNDERS JOHN
    权利人:DUPONT PHARMACEUTICALS RES LAB
    摘要:This invention features methods of biphasic synthesis for synthesizing combinatorial libraries and combinatorial libraries of chemical compounds utilizing the template, and combinatorial libraries of chemical compounds formed by the methods of this invention.

    专利号:US-8664402-B2
    优先权日:2011-03-09
    标题:Process for preparing 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone, an intermediate of etoricoxib
    发明人:CASTELLIN ANDREA; STABILE PAOLO; FONTANA FRANCESCO; DE LUCCHI OTTORINO; CAPORALE ANDREA; TARTAGGIA STEFANO
    权利人:CASTELLIN ANDREA; STABILE PAOLO; FONTANA FRANCESCO; DE LUCCHI OTTORINO; CAPORALE ANDREA; TARTAGGIA STEFANO; ITALIANA SINT SPA
    摘要:A process for preparing 1-(6-methylpyridin-3-yl)-2-[4-(methyl sulfonyl)phenyl]ethanone, an intermediate of the synthesis of Etoricoxib. The synthesis of the intermediates useful for such preparation is also described.
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    合成参考文献


    摘要:Davies, H. M. L.; Morton, D., Science of Synthesis: Stereoselective Synthesis, (2011) 3, 551.
    摘要:Driver, T. G., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 314.
    摘要:Hudson, R.; Moores, A., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 72.
    摘要:Chen, P.; Liu, G., Science of Synthesis: Catalytic Oxidation in Organic Synthesis, (2017) 1, 204.
    摘要:Parmeggiani, F.; Galman, J. L.; Montgomery, S. L.; Turner, N. J., Science of Synthesis, (2019) , 389.
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