CAS: 851335-07-4; 4-Borono-3-Fluorobenzoic Acid

上下游产品

2-氟-4-甲酰基苯硼酸 (2-Fluoro-4-Formylphenyl)Boronic Acid 871126-22-6

2-氟-4-甲酰基苯硼酸置于potassium Permanganate体系中,化学反应生成 4-羧基-2-氟苯硼酸
参考文献:Ortho-Substituted Aryl Monoboronic Acids Have Improved Selectivity For D-Glucose Relative To D-Fructose And L-Lactate
标题:Ortho-Substituted Aryl Monoboronic Acids Have Improved Selectivity For D-Glucose Relative To D-Fructose And L-Lactate
摘要:Ortho-Substituted Aryl Monoboronic Acids Have Been Found To Have Improved Selectivity For D-Glucose Compared To D-Fructose And L-Lactate. These Findings Are Supported By Computational Studies On The B3Lyp/6-31G(D) Level Using Gaussian. This Finding Is Of Interest For Development Of Boronate Based D-Glucose Sensors. (C) 2010 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Tet.2010.11.062

专利信息

专利号:US-12227528-B2
优先权日:2017-11-09
标 题:Glucose-sensitive albumin-binding derivatives
发明人：KRUSE THOMAS; KOFOD-HANSEN MIKAEL; MUENZEL MARTIN WERNER BORCHSENIUS; THOEGERSEN HENNING; SAUERBERG PER; EWALD JAKOB; BEHRENS CARSTEN; HOEG-JENSEN THOMAS; BALSANEK VOJTECH; DROBNAKOVA ZUZANA; DROZ LADISLAV; HAVRANEK MIROSLAV; KOTEK VLADISLAV; STENGL MILAN; SNAJDR IVAN; DRUSANOVA HANA
权利人:NOVO NORDISK AS
摘要:This invention relates to glucose-sensitive albumin-binding diboron conjugates. More particularly the invention provides novel diboron compounds, and in particular diboronate or diboroxole compounds, useful as intermediate compounds for the synthesis of diboron conjugates.