CAS: 107-94-8; 3-Chloropropionic Acid

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CAS号79-10-7 丙烯酸 | CAS号542-76-7 β-氯丙腈 | CAS号109-78-4 3-羟基丙腈 | CAS号57-57-8 丙内酯 | CAS号627-30-5 3-氯-1-丙醇 | CAS号1070-78-6 1,1,1,3-四氯丙烷 | CAS号107-13-1 丙烯腈 | CAS号590-92-1 3-溴丙酸 | CAS号40861-09-4 3-chloroperprop... | CAS号106664-87-3 3-cyclohexylsul... | CAS号10534-99-3 Propanoicacid, ... | CAS号58228-89-0 3-(4-氰基苯氧基)丙酸 | CAS号111140-92-2 3-(4-氨基甲酰苯氧基)丙酸 | CAS号35999-20-3 3-氯-4'-甲氧基苯丙酮 | CAS号32705-91-2 乙二胺-N,N`-二丙酸二盐酸盐 | CAS号544-40-1 二丁基硫醚 | CAS号629-45-8 二丁基二硫醚 | CAS号22002-73-9 3-(丁基硫代)丙酸

β-氯丙腈置于盐酸体系中,化学反应生成3-氯丙酸
参考文献:Jakubowitsch; Merkulowa,Zhurnal Obshchei Khimii,1946,Vol. 16,P. 57
标题:Jakubowitsch; Merkulowa,Zhurnal Obshchei Khimii,1946,Vol. 16,P. 57

专利信息

专利号:US-4400550-A
优先权日:1982-02-12
标题 :Synthesis of the navel orange worm pheromone (Z,Z)-11,13-hexadecadienal
发明人：BISHOP CLYDE E; MORROW GARY W
权利人:ALBANY INT CORP
摘要:A process for the synthesis of (Z,Z)-11-13-hexadecadienal is disclosed, starting with undecylenic alcohol.

专利号:US-5714127-A
优先权日:1992-10-08
标题 :System for multiple simultaneous synthesis
发明人：DEWITT SHEILA H H; KIELY JOHN S; PAVIA MICHAEL R; SCHROEDER MEL C; STANKOVIC CHARLES J
权利人:WARNER LAMBERT CO
摘要:A system for the multiple, simultaneous synthesis of compounds preferably uses a reaction apparatus comprising a reservoir rack having a plurality of reaction wells, a plurality of reaction tubes, usually gas dispersion tubes, having filters on their lower ends, a holder block, having a plurality of apertures, and a manifold, which has ports to allow introduction/maintenance of a controlled environment. The manifold top wall has a plurality of apertures in axial alignment with the reaction tubes and a gasket which allows penetration by a needle in order to dispense and aspirate materials from the reaction tubes. Sealing members, such as gaskets, are placed between the holder block, manifold and reservoir rack and the components are releasably fastened together. A robotic sample processor is used to automate the synthesis process using the reaction apparatus.

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:US-5702672-A
优先权日:1992-10-08
标 题 :Apparatus and method for multiple simultaneous synthesis
发明人：DEWITT SHEILA H H; KELL MICHAEL; PAVIA MICHAEL R; KIELY JOHN S; SCHROEDER MEL C; STANKOVIC CHARLES J; WARE STEVEN
权利人:WARNER LAMBERT CO
摘要:An apparatus for multiple, simultaneous synthesis of compounds which consists of: a reservoir block having a plurality of wells; a plurality of reaction tubes, usually gas dispersion tubes, having filters on their lower ends; a holder block, having a plurality of apertures; and a manifold, which may have ports to allow introduction/maintenance of a controlled environment. The manifold top wall has apertures and a detachable plate with identical apertures. The apparatus is constructed from materials which will accommodate heating, cooling, agitation, or corrosive reagents. Gaskets are placed between the components. Rods or clamps are provided for fastening the components together. Apparatus operation involves placing the filters on the lower ends of the reaction tubes in the reservoir block wells, and the upper ends passing through the holder block apertures and into the manifold.

专利号:WO-2018193463-A1
优先权日:2017-04-21
标题 :An improved process for the preparation of tetrahydroisoquinoline compounds
发明人：DALVI MAHESH BHAGOJI; KENNY RAJESH SHASHIKANT; PATIL AJIT AAPPA; PALKAR TUSHAR TANAJI
权利人:NEON LABORATORIES LTD
摘要:The present invention discloses an improved process for preparation of substantially pure pentamethylene bis(1-(3,4-dimethoxybenzyl)-3,4-dihydro-6,7- dimethoxy-1H-isoquinoline-2-propionate), a compound of formula I and its acid addition salts in good yields. Pentamethylene bis(1-(3,4-dimethoxybenzyl)-3,4- dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate) or its acid addition salts is the key intermediate for the synthesis of a non-depolarizing neuromuscular-blocking drugs. The process can also be used for the synthesis of various tetrahydroisoquinoline derivatives.

专利号:US-2006052577-A1
优先权日:2001-02-06
标题:Methods of synthesis of polymers and copolymers from natural products
发明人：SWIFT GRAHAM; WESTMORELAND DAVID G; HUGHES KATHLEEN
权利人:SWIFT GRAHAM; WESTMORELAND DAVID G; HUGHES KATHLEEN
摘要:Described are polymers and copolymers containing sorbitol, citric acid, starch, aspartic acid, succinic anhydride, adipic acid mixtures thereof, methods of their synthesis and their uses.