CAS: 763-13-3; But-3-Enyl(Trimethyl)Silane

该化合物是有机硅化合物,其特点是,三甲基硅酸混合物中含有一个丁基苯基化合物,该化合物一般是无色液体,由于在丁基汞中存在双联产物,因此具有反应性,可以参与各种化学反应,包括聚合和交叉反应;三甲基硅混合物组提供了稳定性,提高了该化合物在有机溶剂中的溶性. 3-丁基甲基硅经常被用作有机合成中的试剂,特别是用于制作硅烷聚合物,并用作形成硅基材料的混合剂;其独特的结构使得硅能够引入有机框架,使其在材料科学和化学制造中具有价值;在处理该化合物时,应注意安全防范,因为如果吸入或吸入,可能会对健康造成危害.

结构式图片

欧盟法规

C&L通报

上下游产品

CAS号5162-44-7 4-溴-1-丁烯 | CAS号75-77-4 三甲基氯硅烷 | CAS号3528-12-9 Trimethyl[(2E)-... | CAS号16054-35-6 2,7-Disila°Ct-4... | CAS号16054-34-5 (Z)-1,4-bis(tri... | CAS号33558-80-4 Silane,3-buten-... | CAS号762-72-1 烯丙基三甲基硅烷 | CAS号13170-43-9 (三甲基硅基)甲基氯化镁 | CAS号106-95-6 烯丙基溴 | CAS号75-79-6 甲基三氯硅烷 | CAS号31594-49-7 1-cyclopropylpe... | CAS号14113-96-3 1,2-二环丙基乙酮 | CAS号4160-75-2 1-环丙基丙酮 | CAS号1627-98-1 1,1,3,3-四甲基-1,3... | CAS号75-76-3 四甲基硅烷 | CAS号3439-38-1 乙基三甲基硅烷 | CAS号754-05-2 三甲基硅乙烯 | CAS号762-72-1 烯丙基三甲基硅烷 | CAS号16722-10-4 trimethyl-[2-(o... | CAS号3240-29-7 1-苯基-4-戊烯-1-酮

合成工艺路线路线简述

    (Z)-1,4-Bis(Trimethylsilyl)-2-Butene置于三氟乙酸体系中,化学反应 3.0H,以100%的收率获得产物3-丁烯基三甲基硅烷
    参考文献:Salimgareeva,I. M.; Zhebarov,O. Zh.; Bogatova,N. G.,Journal Of General Chemistry Of The Ussr,1981,Vol. 51,# 2,P. 342-346
    标题:Salimgareeva,I. M.; Zhebarov,O. Zh.; Bogatova,N. G.,Journal Of General Chemistry Of The Ussr,1981,Vol. 51,# 2,P. 342-346

    海关参考信息

    专利信息


    专利号:US-7230101-B1
    优先权日:2002-08-28
    标 题:Synthesis of methotrexate-containing heterodimeric molecules
    发明人:MURTHI KRISHNA K; SMITH CHASE C
    权利人:GPC BIOTECH INC
    摘要:The present invention relates to novel compositions of methotrexate-containing heterodimeric probe molecules, also known as chemical inducers of dimerization (CID), useful in three-hybrid assays. The invention further relates to synthesis of said compositions and their intermediates. Another aspect of the invention is a method for using the heterodimeric probe molecules described herein in drug screens to identify potential protein targets to a given ligand, optimize protein-ligand interactions, or identify potential ligands for a given protein target. In certain embodiments, the invention contemplates the synthesis of the following methotrexate-containing heterodimeric probe:

    专利号:US-2012215002-A1
    优先权日:2009-10-09
    标 题:Synthesis of optically active intermediate for the preparation of montelukast
    发明人:LEFORT LAURENT
    权利人:LEFORT LAURENT
    摘要:The present invention relates to the synthesis of optically active alcohols by means of enantioselective hydrogenation of ketones in biphasic systems. In particular the present invention relates to the synthesis of an optically active alcohol of general formula (1).

    专利号:US-8263784-B2
    优先权日:2008-10-30
    标 题 :Method for the synthesis of a ramipril intermediate
    发明人:DE LANGE BEN; HEEMSKERK DENNIS
    权利人:DE LANGE BEN; HEEMSKERK DENNIS; DSM SINOCHEM PHARM NL BV
    摘要:The present invention relates to a process for the preparation of octahydrocyclopenta[b]pyrrole-2-carboxylic acid and esters thereof of general formula (1) in the presence of a cobalt and/or nickel comprising catalyst and to the use of compounds of general formula (1) in the synthesis of ramipril.

    专利号:US-2005014954-A1
    优先权日:2001-11-22
    标 题:Pyrrole synthesis
    发明人:OHRLEIN REINHOLD; BAISCH GABRIELE
    摘要:The invention relates to a novel process for the preparation of N-substituted pyrroles, especially of formula (V), wherein the radicals are as defined in the description, by intermolecular aza-Wittig reaction starting from organic azides and 1,4-dioxo compounds. The invention relates also to novel iminophosphorane intermediates for this synthesis. The resulting pyrroles are useful, for example, in the organic synthesis of pharmaceuticals or other active substances and chemicals.

    专利号:US-7193077-B2
    优先权日:2003-08-30
    标 题 :Exocyclic amine triaryl methyl protecting groups in two-step polynucleotide synthesis
    发明人:DELLINGER DOUGLAS J; SIERZCHALA AGNIESZKA B; CARUTHERS MARVIN H
    权利人:AGILENT TECHNOLOGIES INC
    摘要:Precursors for use in the synthesis of polynucleotides and methods of using the precursors in synthesizing polynucleotides are disclosed. The precursors include a heterocyclic base having an exocyclic amine group and a substituted or unsubstituted triaryl methyl protecting group bound to the exocyclic amine group.

    专利号:US-7427679-B2
    优先权日:2003-08-30
    标 题:Precursors for two-step polynucleotide synthesis
    发明人:DELLINGER DOUGLAS J; SIERZCHALA AGNIESZKA B; CARUTHERS MARVIN H
    权利人:AGILENT TECHNOLOGIES INC
    摘要:Precursors for use in the synthesis of polynucleotides are disclosed. The precursors include a heterocyclic base having an exocyclic amine group and a substituted or unsubstituted triaryl methyl protecting group bound to the exocyclic amine group. In particular embodiments, the precursor has the structure: n nwherein:n O and H represent oxygen and hydrogen, respectively, R 1 is hydrido, hydroxyl, protected hydroxyl, lower alkyl, modified lower alkyl, or alkoxy, one of R 2 or R 3 is a hydroxyl protecting group; and the other of R 2 or R 3 is a reactive group capable of reacting with a reactive site hydroxyl, Base is a heterocyclic base having an exocyclic amine group, and Tram is a triaryl methyl group having the structure (V) n nwherein the broken line represents a bond to the amino nitrogen of the exocyclic amine group, and R 4 , R 5 and R 6 are independently selected from unsubstituted or substituted aryl groups, provided that at least one of R 4 , R 5 , and R 6 is an aryl group other than phenyl and other than substituted phenyl.
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    合成参考文献


    摘要:Michalak, M.; Gulajski, L.; Grela, K., Science of Synthesis, (2010) 47, 354.
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