CAS: 103-90-2; Paracetamol

上下游产品

CAS号105326-63-4 N-[4-(2-喹啉甲氧基)苯基]乙酰胺 | CAS号109690-44-0 [4-[2-(4-azaniu... | CAS号30824-21-6 4-乙酰氨基苯基-2,3,4-... | CAS号3273-78-7 Benzenamine,4,4... | CAS号50375-15-0 N-[4-(羟基乙氧基)苯基]乙酰胺 | CAS号32113-41-0 4 -乙酰氨基酚硫酸钾盐 | CAS号39149-13-8 2-(4-乙酰氨基苯氧基)乙酸 | CAS号52980-20-8 4,4'-(1,3-丙二基)二氧二苯胺 | CAS号50700-49-7 N-乙酰苯醌亚胺 | CAS号98555-06-7 4-acetamido-2-d...

N-乙酰苯胺置于glucose Dehydrogenase,葡萄糖,Cytochrome P450Bm3From Bacillus Megaterium F87A/h171L/a184I/q307H/n319Y/a328I Mutant,C21H27N7O17P3(1-)*na(1+)*h(1+)体系中,用 Aq. Phosphate Buffer 用作溶剂,化学反应 16.0H,反应生成对乙酰氨基酚
参考文献:工程化细胞色素p450 Bm3对苯甲酸酯的羟基化作用
标题:工程化细胞色素p450 Bm3对苯甲酸酯的羟基化作用
摘要:已使用突变型细胞色素p450 Bm3酶以制备规模实现了对苯甲酸酯的生物催化直接单羟基化反应.在大多数情况下,代表性的单取代和二取代的n-三氟甲磺酰苯胺显示已转化为相应的4-羟基衍生物,而在两种情况下也发生了取代基羟基化.通过突变变异,可以实现环或侧链位点的选择性羟基化.
Doi:10.1039/c7Ob02236K

专利信息

专利号:US-7759520-B2
优先权日:1996-11-27
标 题 :Synthesis of selective androgen receptor modulators
发明人：DALTON JAMES T; MILLER DUANE D; YIN DONGHUA; HE YALI
权利人:UNIV TENNESSEE RES FOUNDATION
摘要:The present invention relates to a synthetic process for the preparation of a novel class of androgen receptor targeting agents (ARTA) which demonstrate androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. The agents define a new subclass of compounds which are selective androgen receptor modulators (SARM) which are useful for a) male contraception; b) treatment of a variety of hormone-related conditions, for example conditions associated with Androgen Decline in Aging Male (ADAM), such as fatigue, depression, decreased libido, sexual dysfunction, erectile dysfunction, hypogonadism, osteoporosis, hair loss, anemia, obesity, sarcopenia, osteopenia, osteoporosis, benign prostate hyperplasia, alterations in mood and cognition and prostate cancer; c) treatment of conditions associated with Androgen Decline in Female (ADIF), such as sexual dysfunction, decreased sexual libido, hypogonadism, sarcopenia, osteopenia, osteoporosis, alterations in cognition and mood, depression, anemia, hair loss, obesity, endometriosis, breast cancer, uterine cancer and ovarian cancer; d) treatment and/or prevention of chronic muscular wasting; e) decreasing the incidence of, halting or causing a regression of prostate cancer; f) oral androgen relacement and/or other clinical therpauetic and/or diagnostic areas. The process of the present invention is suitable for large-scale preparation, since all of the steps give rise to highly pure compounds, thus avoiding complicated purification procedures which ultimately lower the yield. Thus the present invention provides methods for the synthesis of non-steroidal agonist compounds, that can be used for industrial large-scale synthesis, and that provide highly pure products in high yield.

专利号:US-10472241-B2
优先权日:2015-10-06
标 题:Process for the synthesis of carbon nanotubes
发明人：GOSWAMI GOPAL KRISHNA; PATIL SWANAND DILIP; VEEDU SREEKUMAR THALIYIL; BALACHANDRAN VIJAI SHANKAR
权利人:RELIANCE INDUSTRIES LTD
摘要:The present disclosure relates to a process for the synthesis of highly crystalline carbon nanotubes (CNTs). Processes known in the art employ post-synthesis processes such as oxidation or hydrothermal treatment to produce CNTs with high crystallinity. The present disclosure produces highly crystalline CNTs at a low growth temperature and without hydrogen flow condition and without employing any post-production process. The process disclosed in the present disclosure produces CNTs having a crystallinity greater than 5 which makes them suitable for various industrial applications.

专利号:US-6995284-B2
优先权日:2000-08-24
标题 :Synthesis of selective androgen receptor modulators
发明人：DALTON JAMES T; MILLER DUANE D; HE YALI; YIN DONGHUA
权利人:UNIV TENNESSEE RES FOUNDATION
摘要:The present invention relates to a synthetic process for the preparation of a novel class of androgen receptor targeting agents (ARTA) which demonstrate androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. The agents define a new subclass of compounds which are selective androgen receptor modulators (SARM) which are useful for a) male contraception; b) treatment of a variety of hormone-related conditions, for example conditions associated with Androgen Decline in Aging Male (ADAM), such as fatigue, depression, decreased libido, sexual dysfunction, erectile dysfunction, hypogonadism, osteoporosis, hair loss, anemia, obesity, sarcopenia, osteopenia, osteoporosis, benign prostate hyperplasia, alterations in mood and cognition and prostate cancer; c) treatment of conditions associated with Androgen Decline in Female (ADIF), such as sexual dysfunction, decreased sexual libido, hypogonadism, sarcopenia, osteopenia, osteoporosis, alterations in cognition and mood, depression, anemia, hair loss, obesity, endometriosis, breast cancer, uterine cancer and ovarian cancer; d) treatment and/or prevention of chronic muscular wasting; e) decreasing the incidence of, halting or causing a regression of prostate cancer; f) oral androgen relacement and/or other clinical therpauetic and/or diagnostic areas. The process of the present invention is suitable for large-scale preparation, since all of the steps give rise to highly pure compounds, thus avoiding complicated purification procedures which ultimately lower the yield. Thus the present invention provides methods for the synthesis of non-steroidal agonist compounds, that can be used for industrial large-scale synthesis, and that provide highly pure products in high yield.

专利号:US-8679445-B1
优先权日:2013-11-14
标题:Synthesis of CsSnI3 by temperature gradient solid-phase sintering method
发明人：REN YUHANG; ZHANG JIN; LI YIZHI; SHUM KAI
权利人:SUN HARMONICS LTD
摘要:This invention discloses a solid-based synthesis of cesium tin tri-iodide (CsSnI 3 ). More specifically, the CsSnI 3 is fabricated in a 3 zone high temperature resisting tube by the solid-phase sintering method. CsSnI 3 are ideally suited for a wide range of applications such as light emitting and photovoltaic devices.

专利号:WO-2025094207-A1
优先权日:2023-10-30
标题 :A solvent free, single step continuous process for the synthesis of paracetamol
发明人：KULKARNI AMOL ARVINDRAO; SHAIKH TABREZ; ATAPALKAR RANJIT SHABU; PALGHADMAL ANIL VAMANRAO
权利人:COUNCIL SCIENT IND RES
摘要:The present invention provides a continuous single step, solvent free and additive free process for the synthesis of Paracetamol with more than 90% conversion of the solid substrates and at least 94-97% selectivity towards paracetamol as product, and that to without the need of any solvent in a screw reactor.

专利号:US-2002055171-A1
优先权日:1998-05-27
标题 :Preparation of biologically active 3-methyleneoxindole and definition of its application in stimulation of plant growth and tissue repair
发明人：TULI VIRENDA KUMAR
摘要:Identification of the true nature and metabolic action of 3 -methyleneoxindole (MO), a naturally occurring catabolite of the plant auxin, indole- 3 -acetic acid (IAA). Description of the two novel methods of synthesis of MO which produce the pure, biologically active auxin compound of MO. Discovery and description of the causes for the erroneous classification of MO as an inert compound with no auxin activity. These findings and methods of synthesis correct the ubiquitous theoretical errors which have driven scientific investigation and plant science research of plant auxins for nearly forty years. n Researchers have failed to observe the auxin activity of MO because of the use of standard but incorrect synthetic techniques which have consistently produced impure forms of 3 -bromooxindole- 3 -acetic acid ( 3 -Brox), the synthetic precursor of MO. In addition, the use of dimethylsulfooxide as a solvent for MO has been identified as a major source of contamination of MO during synthesis. n This invention describes two novel methods for synthesizing (MO). By using purified MO and avoiding the use of dimethylsulfoxide, it was found that the resulting MO product to be 100 to 1,00 fold more effective than IAA in promoting rooting in plant cuttings; supporting tissue differentiation and growth in stage I, stage II and stage III media used for the micropropagation of explants; promoting the formation of callus tissue over wounded plant parts; and, stimulating the production of interstitial tissue between scion and rootstock to increase the success rate for grafting. Therefore, this invention identifies MO as the dominant auxin in shoot acceleration, root development, wound sealing and scion acceptance. n Finally, the correct pathway from IAA to MO is presented.