CAS: 13461-74-0; 9-Ethynyl-9H-Fluoren-9-Ol

相似化合物

6311-22-4 713131-50-1 2798950-28-2

上下游产品

9-fluorenone sodium acetylide acetylene lithium acetylide-ethylenediamine complex 9-(5-hydroxy-5,5-diphenyl-penta-1,3-diynyl)-fluoren-9-ol (9))-propinol-(1)1,1-Bis-(4-methoxyphenyl)-3-(9-hydroxyfluorenyl(9))-propinol-(1) -fluoranthen7.10-Diphenyl-8-9-hydroxy-fluorenyl-(9)-fluoranthen -aethinyl)-9,10-dihydro-anthracen9-Hydroxy-10-phenylimino-9-(9-hydroxy-fluorenyl-(9)-aethinyl)-9,10-dihydro-anthracen

9-芴酮置于正丁基锂,四丁基氟化铵体系中,用 四氢呋喃,正己烷 用作溶剂,化学反应 2.08H,反应生成9-乙炔-9-芴醇
参考文献:通过对苯二酚的邻-Nqm的半松果醇重排构建部分保护的不对称联芳基二醇
标题:通过对苯二酚的邻-Nqm的半松果醇重排构建部分保护的不对称联芳基二醇
摘要:已经实现了由agbf 4催化的部分保护的不对称联芳基二醇的构建.该方法通过邻-Nqm生成/ Semipinacol重排级联促进了两个新的芳基环的形成和两个羟基的引入(一个游离基和一个tbs保护基),具有高原子经济性和阶梯经济性,可提供多种阵列温和条件下制备部分保护的不对称联芳基二醇.
Doi:10.1021/acs.Orglett.0C03717

专利信息

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:US-2003082830-A1
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products

专利号:WO-0006525-A9
优先权日:1998-07-25
标题:Synthesis of combinatorial libraries of compounds reminiscent of natural products

专利号:WO-0006525-A2
优先权日:1998-07-25
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products

专利号:US-6448443-B1
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products

专利号:CN-101638420-B
优先权日:2009-01-14
标题:Synthesis method of phosphoryne bond