专利号:US-7087783-B2 优先权日:2000-05-29 标 题 :Method for preparing nitrogen-containing compounds 发明人:EMURA TAKASHI; HANEISHI TSUYOSHI 权利人:CHUGAI PHARMACEUTICAL CO LTD 摘要:A synthesis method which comprises reacting NH group-containing compounds with thiocyanates, cyanamides, nitriles or esters in the presence of a silylating agent to synthesize the corresponding nitrogen-containing addition or substitution products. This method not only enables the direct and efficient synthesis of nitrogen-containing compounds including isothioureas, guanidines, amidines and amides, but it also has a wide range of applications and is suitable for large-scale synthesis.
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