CAS: 660-88-8; 5-Aminopentanoic Acid

相似化合物

627-95-2 2173111-73-2 123622-48-0

上下游产品

piperidin-2-one Adipic acid N-benzoylpiperidine 2-(3-bromopropyl)isoindole-1,3-dione 5-(N-phthalimido)pentanoic acid 5-benzoylaminopentanoic acid -aminovaleric acid ethyl ester p-toluoylamino-valeric acid5-p-toluoylamino-valeric acid

L-赖氨酸置于水体系中,化学反应 5.0H,以95%的收率获得产物5-氨基颉草酸
参考文献:有效的酶促合成5-氨基戊酸
标题:有效的酶促合成5-氨基戊酸
摘要:由i-赖氨酸酶促制备标题化合物,产率高且在无缓冲液的条件下.通过来自木霉属木霉的1-赖氨酸α-氧化酶的作用将1-赖氨酸氧化,然后在反应介质中将中间体6-氨基-2-氧杂己酸自发地氧化脱羧.将1-赖氨酸α-氧化酶固定在环氧活化的固体支持物(sepabeads Ec-Ep)上,并测定该反应中溶液基和固定酶的活性.
DOI:10.1016/j.Molcatb.2009.12.006

专利信息

专利号:US-2006264608-A1
优先权日:2001-08-03
标题 :Bi-directional synthesis of oligoguanidine transport agents
发明人：WENDER PAUL A; VANDEUSEN CHRISTOPHER L; PATTABIRAMAN KANAKA; PELKEY ERIN T; JESSOP THEODORE C
权利人:WENDER PAUL A; VANDEUSEN CHRISTOPHER L; PATTABIRAMAN KANAKA; PELKEY ERIN T; JESSOP THEODORE C
摘要:Synthesis routes that can be adapted to large scale synthesis of oligoguanidine compounds such as oligoarginine compounds are described which use a perguanidinylation step to convert a group of ω-amino groups to the corresponding guanidinyl groups. These compounds find utility as transport agents. Modified oligoguanidine compounds are also described.

专利号:US-7067698-B2
优先权日:2001-08-03
标 题 :Bi-directional synthesis of oligoguanidine transport agents
发明人：WENDER PAUL A; VANDEUSEN CHRISTOPHER L; PATTABIRAMAN KANAKA; PELKEY ERIN T; JESSOP THEODORE C
权利人:UNIV LELAND STANFORD JUNIOR
摘要:Synthesis routes that can be adapted to large scale synthesis of oligoguanidine compounds such as oligoarginine compounds are described which use a perguanidinylation step to convert a group of ω-amino groups to the corresponding guanidinyl groups. These compounds find utility as transport agents. Modified oligoguanidine compounds are also described.

专利号:WO-9507882-A1
优先权日:1993-09-14
标 题:Synthesis of amido acids from carboxylic acid esters and amino acid salts
发明人：HEINZMAN STEPHEN WAYNE; DUPONT JEFFREY SCOTT
权利人:PROCTER & GAMBLE
摘要:Chemical synthesis of amido acids, and their conversion to amido acid phenyl ester sulfonates for use as bleach activators, starting from carboxylic acid esters and amino acid salts.

专利号:US-8748651-B2
优先权日:2008-11-17
标题:Method for the synthesis of an omega-amino acid or ester starting from a monounsaturated fatty acid or ester
发明人：DUBOIS JEAN-LUC
权利人:DUBOIS JEAN-LUC; ARKEMA FRANCE
摘要:The invention relates to a method for the synthesis of ω-amino alkanoic acids or esters thereof starting from unsaturated natural fatty acids passing through an ω-unsaturated nitrile intermediate compound.

专利号:US-5886104-A
优先权日:1993-06-18
标题 :Grafted cross-linked polyolefin substrates for peptide synthesis and assays
发明人：PEDERSEN WALTHER BATSBERG; ALMDAL KRISTOFFER; WINTHER LARS; BERG ROLF HENRIK
权利人:FORSKNIINGSCENTER RISO
摘要:A solid support for the solid-phase synthesis of peptides or proteins in high yield and in high purity, suited both to the synthesis of a single peptide or protein and to the parallel and substantially simultaneous synthesis of a plurality thereof, is based on a cross-linked polyolefin, especially polyethylene, substrate, the cross-linking having been obtained by irradiation with high energy electrons or γ radiation or treatment with organic peroxide such as benzoyl peroxide, to which substrate are grafted polymer chains such as polystyrene chains which are functionalized with a chemical functionality facilitating the formation of an anchoring linkage between the polymer moiety and another chemical species. The solid support is also suited for use in solid-phase biosystems, notably bioassays, such as immunoassays, DNA hybridization assays or PCR amplification. The grafted chains may bear substituents which are such that the polymer-grafted cross-linked polyolefin substrate is swellable by water or aqueous media, in other words, hydrophilic, which makes the solid support particularly well suited for assays of the ELISA type.

专利号:WO-9931124-A1
优先权日:1997-12-12
标 题:Cholic acid-based scaffolds for multidimensional molecular presentation of peptides
发明人：HOEEG-JENSEN THOMAS
权利人:NOVO NORDISK AS; HOEEG JENSEN THOMAS
摘要:A solid phase method for the synthesis of a plurality of differently substituted cholic acid scaffolds with a wide variety of peptide chain, pseudo-peptide chain or peptoid chain substitutents, as leads or compounds of potential therapeutic interest. The substituted cholic acids are prepared by initial solution synthesis of a scaffold holding amino acids with 3 orthogonal protecting groups. Subsequent solid-phase synthesis provides the build-up of the target molecules, either as discretes or in mixture. The molecules may be screened on the resin or cleaved from the resin and then screened in solution. The method disclosed here provides an easy and fast access to highly diverse compounds, potential peptide mimetics and potential leads for compounds of therapeutic interest. The method is amenable to automatization.