CAS: 319-03-9; 5-Fluoroisobenzofuran-1,3-Dione

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CAS号5466-84-2 4-硝基邻苯二甲酸酐 | CAS号320-96-7 diethyl 4-fluor... | CAS号118-45-6 4-氯代苯酐 | CAS号320-97-8 4-氟邻苯二甲酸 | CAS号38103-06-9 双酚A二酐(BPADA) | CAS号57584-71-1 5-氟异吲哚啉 | CAS号1823-59-2 4,4'-联苯醚二酐 | CAS号444717-62-8 5-fluoro-2-(4-n... | CAS号62558-08-1 4-氟-1,2-苯二甲醇 | CAS号55831-04-4 1,2-二(溴甲基)-4-氟苯

4-硝基邻苯二甲酸酐置于potassium Fluoride体系中,用 二氯甲烷,乙腈 作为反应溶剂,化学反应生成 4-氟邻苯二甲酸酐
参考文献:Preparation Of 4-Fluorophthalic Anhydride
标题:Preparation Of 4-Fluorophthalic Anhydride
摘要:4-氟邻苯二酐可以通过将氟化钾与4-硝基邻苯二酐反应制备而成.使用溶剂可以增加反应的反应速率并降低反应温度.更具反应性的4-氟邻苯二酐可用于制备用于聚醚酰亚胺生产的bpa-二酐.

专利信息

专利号:US-5322954-A
优先权日:1993-05-28
标 题 :Synthesis of 4-substituted phthalic anhydrides
发明人：SEPER KARL W; STULTS JEFFREY S; OLSEN GARY H
权利人:OCCIDENTAL CHEM CO
摘要:Disclosed is a method of making a 4-substituted phthalic anhydride. A halomaleic (including halofumaric anhydride (or the acid or ester thereof) is made by the reaction of-maleic anhydride with chlorine or bromine. The halomaleic anhydride is reacted with a conjugated diene to form a first cycloadduct having the formula ##STR1## The first cycloadduct is heated to eliminate HX and produce a second cycloadduct having the formula ##STR2## The second cyclo adduct is dehydrogenated to produce a 4substituted phthalic anhydride which has the formula ##STR3## where R 1 , R 2 , and R 4 are preferably H and R 3 is preferably Cl or F.

专利号:US-2011263540-A1
优先权日:2008-07-25
标题 :Small-molecule inhibitors of protein synthesis inactivating toxins
发明人：PANG YUAN-PING; TUMER NILGUN EREKEN; MILLARD CHARLES B
权利人:PANG YUAN-PING; TUMER NILGUN EREKEN; MILLARD CHARLES B
摘要:Small-molecule inhibitors of a protein synthesis inhibiting toxin, e.g., ricin, abrin, Shiga, and Shiga-like toxins, as well as methods of using the inhibitors are provided. Further provided are methods of identifying small-molecule inhibitors of a protein synthesis inhibiting toxin.

专利号:US-5663449-A
优先权日:1989-05-19
标 题 :Intermediate compounds in the synthesis of heteroarylpiperidines, pyrrolidines and piperazines

专利号:US-7268237-B2
优先权日:2005-03-11
标题:Direct dianhydride synthesis
发明人：BRUNELLE DANIEL JOSEPH; CELLA JAMES ANTHONY; YE QING; CHAN KWOK PONG
权利人:GEN ELECTRIC
摘要:This invention is related to a method for making diether dianhydrides by the reaction of halophthalic anhydride and a metal salt of an aromatic dihydroxy compound in the presence of a solvent and a phase transfer catalyst. Typical phase transfer catalyst include guanidium salts, aminopyridinium salts, or phosphazenium salts.

专利号:WO-2024035626-A1
优先权日:2022-08-11
标 题:Halophthalimide compounds and methods of use against tbi, inflammatory disorder, autoimmune disorder, neurodegenerative disease or viral infection
发明人：GREIG NIGEL; LUO WEIMING; TWEEDIE DAVID; SCERBA MICHAEL; LECCA DANIELA; HSUEH SHIH CHANG; KIM DONG SEOK
权利人:US HEALTH; AEVISBIO INC
摘要:Halophthalimides are disclosed. The halophthalimides may inhibit TNF-α activity, TNF-α synthesis, inflammation, inducible nitric oxide synthase, SARS-CoV-2 virus, or any combination thereof. The halophthalimides may be administered to a subject with a traumatic brain injury, an inflammatory disorder, an autoimmune disorder, a neurodegenerative disease, a viral infection, or any combination thereof. The disclosed halophthalimides have a structure according to Formula (I), or a stereoisomer or pharmaceutically acceptable salt, solvate, or hydrate thereof,

专利号:US-5637710-A
优先权日:1989-05-19
标题:Intermediate compounds in the synthesis of heteroarylpiperidines and piperazines