CAS: 335-64-8; 2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Pentadecafluorooctanoyl Chloride

该化合物是一种全氟有机化合物,其独特结构包括一个长碳链,完全取代氟原子,以碳化物功能组别终止,该化合物一般为无色液体或固体,在室温下,由于碳-氟联结强,其稳定性和抗热和化学降解的能力很高,众所周知.全氟辛基氯化物具有高度反应性,特别是核糖核,因此在各种化学合成应用中有用,包括生产氟表面活性剂和聚合物,其特性还包括低表面紧张度和高缺水性,这有助于其在涂层和乳化器等应用中的效力,然而,由于与全氟化合物相关的环境和健康问题,其使用须接受监管审查.适当处理和处置对于减轻与接触该化合物有关的潜在风险至关重要.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号335-67-1 全氟辛酸 | CAS号376-27-2 十五氟辛酸甲酯 | CAS号307-35-7 全氟辛基磺酰氟 | CAS号335-95-5 全氟辛酸钠 | CAS号376-27-2 十五氟辛酸甲酯 | CAS号423-54-1 二氯异氰尿酸纳 | CAS号307-62-0 全氟十四烷 | CAS号375-89-3 1-Chloroperfluo... | CAS号55756-24-6 1H-全氟-1-辛炔 | CAS号307-30-2 1H,1H-十五氟-1-辛醇 | CAS号307-29-9 1H,1H-全氟辛基胺 | CAS号36554-97-9 9H,9H-三十氟-8,10-十七烷二酮 | CAS号2358-22-7 十三氟庚酰胺 | CAS号2395-00-8 全氟辛酸钾

合成工艺路线路线简述

    全氟辛酸置于苯甲酰氯体系中,用77%的收率获得产物全氟辛酰氯
    参考文献:α,α-二卤代氟甲基全氟烷基酮的区域特异性制备
    标题:α,α-二卤代氟甲基全氟烷基酮的区域特异性制备
    摘要:-磷鎓盐与-酰氯的酰化以高收率得到相应的-全氟甜菜碱.随后的氯化或溴化区域特异性地产生α,α-二卤代氟甲基全氟烷基酮.
    DOI:10.1016/s0040-4039(00)83859-9

    海关参考信息

    专利信息


    专利号:US-6384210-B1
    优先权日:1997-03-20
    标题:Solvent for biopolymer synthesis, solvent microdroplets and methods of use
    发明人:BLANCHARD ALAN P
    权利人:UNIV WASHINGTON
    摘要:The present invention provides a method of biopolymer, esp. oligonucleotide, synthesis. The method consists of coupling a first nucleotide to a second nucleotide in a high surface tension solvent. The invention also provides microdroplets of a soln. comprising a solvent having a b.p. of 150 degree. C. or above, a surface tension of 30 dynes/cm or above, and a viscosity of 0.015 g/(cm)(sec), e.g., propylene carbonate. Such microdroplets are useful for the synthesis of chem. species, particularly biopolymers such as oligonucleotides and peptides, as well as arrays of chem. species. An automated system for oligonucleotide synthesis is described, which comprises delivery of microdroplets by inkjet technol. and computer control of the process. The high surface tension solvent used is selected for compatibility with the inkjet technol.

    专利号:US-6419883-B1
    优先权日:1998-01-16
    标题 :Chemical synthesis using solvent microdroplets
    发明人:BLANCHARD ALAN P
    权利人:UNIV WASHINGTON
    摘要:The present invention relates to microdroplets of a solution comprising a solvent having a boiling point of 150° C. or above, a surface tension of 30 dynes/cm or above, and a viscosity of 0.015 g/(cm)(sec). Such microdroplets are useful for the synthesis of chemical species, particularly biopolymers such as oligonucleotides and peptides, as well as arrays of chemical species. Preferably, the solvent has the formula (I):whereinA=O or S;X=O, S or N (C1-C4 alkyl)Y=O, S, N(C1-C4 alkyl) or CH2; andR=C1-C20 straight or branched chain alkyl.

    专利号:US-6329470-B1
    优先权日:1999-09-30
    标 题:Fluorocarbon end-capped polymers and method of synthesis
    发明人:GARDELLA JR JOSEPH A; HICKS JR WESLEY; KOLOSKI TIMOTHY; LOSITO ILARIO; LEE WON-KI; VARGO TERRENCE G
    权利人:UNIV NEW YORK STATE RES FOUND
    摘要:The present invention provides novel surface modified biodegradable polyesters having fluorocarbon chains at the terminal end of the polyesters. The compounds of the present invention are obtained by the addition of fluorocarbon chains at the surface of the polyester. Any commonly used polyester material can be used in the present invention; however, polyglycolic or polylactic acids or co-polymers thereof are preferred.

    专利号:US-7135598-B2
    优先权日:2002-09-06
    标题:N-vinylformamide derivatives, polymers formed therefrom and synthesis thereof
    发明人:BECKMAN ERIC J; CHAPMAN TOBY M; SHI LIANJUN
    权利人:UNIV PITTSBURGH
    摘要:A method of synthesizing a compound having the formula: n ncomprising the step of:n reacting a N-vinylformamide salt having the formula n n n n n n n n n n n n  with a compound having the formula XR 1 R 2 ; wherein X is Br, Cl or I, M is an alkali metal or an alkali earth metal, R 1 is a C0–C25 alkylene group, a C0–C25 fluroalkylene group or a C0–C25 perfluoro alkylene group, R 2 is H, provided R 1 is not absent, an alkyl group, a fluroalkyl group, a perfluoroalkyl group, an aryl group, a hydroxy group, a polyether group, a heterocyclic group of 5 or 6 atoms wherein at least one of the atoms is not a carbon and is N, O, or S, —OR 3 , wherein, R 3 is an alkyl group, a fluoroalkyl group, a perfluoroalkyl group, or an aryl group, —C(O)R 4 , —C(O)OR 4 , —OC(O)R 4 , —OC(O)R 4 , wherein R 4 is an H, an alkyl group, a fluoroalkyl group, a perfluoroalkyl group, or an aryl group, a phthalimide group or NR 5 R 5 wherein R 5 and R 5 are independently H, —C(O)R 4 , an alkyl, a fluoroalkyl group, a perfluoroalkyl group or an aryl group.

    专利号:CN-119529156-A
    优先权日:2025-01-22
    标题:Method for in-situ synthesis of perfluoroether rubber material by emulsion polymerization

    专利号:CN-119529156-B
    优先权日:2025-01-22
    标 题 :Method for in-situ synthesis of perfluoroether rubber material by emulsion polymerization
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    合成参考文献


    摘要:S25 | OECDPFAS | List of PFAS from the OECD | DOI:10.5281/zenodo.2648775
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