CAS: 500-66-3; Olivetol

上下游产品

CAS号22976-40-5 1,3-Dimethoxy-5... | CAS号53103-15-4 2,4-dihydroxy-6... | CAS号1132-21-4 3,5-二甲氧基苯甲酸 | CAS号17213-57-9 3,5-二甲氧基苯甲酰氯 | CAS号7311-34-4 3.5-二甲氧基苯甲醛 | CAS号99-10-5 3,5-二羟基苯甲酸 | CAS号74732-76-6 5-pentyl-4-(phe... | CAS号705-76-0 3,5-二甲氧基苯甲醇 | CAS号14615-72-6 3,5-二苄氧基苯甲醛 | CAS号5957-75-5 DEA限制 | CAS号1972-08-3 delta9-四氢大麻酚乙醇 | CAS号14992-44-0 Δ4(8)-iso-Tetra... | CAS号13956-29-1 大麻二酚 | CAS号22972-55-0 Abnormal Cannabidiol | CAS号18456-88-7 5-戊基环己烷-1,3-二酮 | CAS号25654-31-3 大麻萜酚 | CAS号55854-24-5 (E)-4-(3,7-dime... | CAS号22976-40-5 1,3-Dimethoxy-5...

3,5-Diamino-1-Pentylbenzene置于硫酸,Sodium Nitrite,Sodium Sulfate体系中,用 二氯甲烷,水 作为反应溶剂,化学反应 1.0H,以78%的收率获得产物3,5-二羟基戊苯
参考文献:3,5-二羟基戊苯的合成方法
标题:3,5-二羟基戊苯的合成方法
摘要:本发明提供了一种3,5‑二羟基戊苯的合成方法,通过在酸催化下对苯进行friedel‑crafts酰基化反应获得苯戊酮,所述酸为路易斯酸;将获得的苯戊酮进行硝化反应获得3,5‑二硝基苯戊酮;再将羰基还原成亚甲基后再还原硝基,获得3,5‑二氨基戊苯;重氮化3,5‑二氨基戊苯变羟基获得3,5‑二羟基戊苯.本发明所使用的原料均为价格低廉易得的大宗化工原料,每一步反应条件都较为温和,属于大量应用于化工行业的常规反应.按照该工艺获得的最终产品3,5‑二羟基戊苯(Olivetol)纯度高,能达到98.5%以上,单杂在0.3%以内.

专利信息

专利号:US-2007287843-A1
优先权日:2004-04-07
标题 :Methods and Intermediates for the Synthesis of Delta-9 Tetrahydrocannabinol
发明人：CABAJ JOHN E; PARIZA RICHARD J; LUKESH JULIE M
权利人:CABAJ JOHN E; PARIZA RICHARD J; LUKESH JULIE M
摘要:Processes are disclosed for the synthesis of Delta-9 tetrahydrocannabinol which result in an improved Y-THC/Y-THC ratio, and intermediates are disclosed that may be used in the synthesis of Delta-9 tetrahydrocannabinol such that improved Y-THCIY-THC ratios are achieved. The intermediates may be cyclic compounds prepared from 2-Carene. There is also provided a scaleable process for the preparation of (+)-p-menth-2-ene-1,8-diol, another intermediate used in the synthesis of delta-9-tetrahydrocannibinol.

专利号:US-11046978-B2
优先权日:2016-03-16
标 题:Synthesis of isoprenoids and derivatives
发明人：GONZALEZ RAMON; CLOMBURG JAMES M; CHEONG SEOKJUNG
权利人:UNIV RICE WILLIAM M
摘要:This disclosure generally relates to the use of enzyme combinations or recombinant microbes comprising same to make isoprenoid precursors, isoprenoids and derivatives thereof including prenylated aromatic compounds. Novel metabolic pathways exploiting Claisen, aldol, and acyioin condensations are used instead of the natural mevalonate (MVA) pathway or 1-deoxy-d-xylulose 5-phosphate (DXP) pathways for generating isoprenoid precursors such as isopentenyl pyrophosphate (IPP), dimethylallyl pyrophosphate (DMAPP), and geranyl pyrophosphate (GPP). These pathways have the potential for better carbon and or energy efficiency than native pathways. Both decarboxylative and non-carboxylative condensations are utilized, enabling product synthesis from a number of different starting compounds. These condensation reactions serve as a platform for the synthesis of isoprenoid precursors when utilized in combination with a variety of metabolic pathways and enzymes for carbon rearrangement and the addition/removal of functional groups. Isoprenoid alcohols are key intermediary products for the production of isoprenoid precursors in these novel synthetic metabolic pathways.

专利号:US-4895922-A
优先权日:1988-05-05
标 题 :Low temperature synthesis of polyesteramides
发明人：OGATA NAOYA
权利人:GOODYEAR TIRE & RUBBER
摘要:This invention disclosed a process for the synthesis of polyesteramides. By utilizing the phosphorus containing catalyst systems of the present invention, such polyesteramides can be synthesized at relatively low temperatures. The present invention specifically discloses a process for the synthesis of a polyesteramide which comprises polymerizing at least one diamine, at least one diol, and at least one dicarboxylic acid in the presence of (1) at least one acid acceptor; (2) at least one halogenated organic compound; and (3) at least one phosphorus containing compound selected from the group consisting of (a) triphenylphosphine, (b) triphenylphosphine oxide, (c) triphenylphosphine sulfide, (d) polymeric agents having pendant diphenylphosphine groups, (e) silicon-phosphorus compositions which contain at least one divalent oxygen atom which is bonded directly to a tetravalent silicon atom and a trivalent or pentavalent phosphorus atom; (f) compounds with the structural formula (C 6 H 5 ) 3 P=N-R, wherein R is a hydrogen atom or an alkyl group containing from 1 to 10 carbon atoms; and (g) compounds with the structural formula (C 6 H 5 )PR 1 R 2 wherein R 1 and R 2 can be the same or different, wherein R 1 is selected from the group consisting of alkyl groups containing from 1 to 10 carbon atoms and phenyl groups, and wherein R 2 is an alkyl group containing from 1 to 10 carbon atoms.

专利号:US-2020079715-A1
优先权日:2018-09-06
标题 :2-position modification for synthesis of resorcinol scaffolding
发明人：DAVIS ROBERT; BLACK JACOB; SMELTZER THOMAS; COLVIN SEAN
权利人:CANOPY HOLDINGS LLC
摘要:A resorcinol with modifications at the 2-position is provided. The reactant resorcinol may have a variety of functional groups at each of the 1, 3, and 5 position such as a hydroxide, a lower alkyl group, a phenyl, a substituted phenyl, a lower alkenyl, or a lower alkynyl sp 2 carbon group (e.g., substituted phenyl, vinyl), sp (e.g., alkyne), hydrogen. The resorcinol is modified at the 2-position with a nucleophile or an electrophile. The resulting resorcinol may serve as a stable intermediate for the synthesis of cannabinoid or cannabinoid derivatives.

专利号:US-11434217-B2
优先权日:2017-12-29
标 题 :Method for synthesis of lobaric acid and analog thereof
发明人：YIM JOUNG HAN; KIM IL-CHAN; HAN SE JONG; YOUN UI JOUNG; LEE HONG KUM; LEE JUN HYUCK; KIM TAI KYOUNG; YEO KWON JOO
权利人:KOREA INST OCEAN SCI & TECH; KOREA INSTITUTE OF OCEAN SCIENCE AND TECH
摘要:The present invention can synthesize lobaric acid and four analogues thereof, which are five phenolic lichen metabolites isolated from an extract of the Antarctic lichen Stereocaulon alpinum and selectively inhibit PTP1B, by a simple, economic and efficient chemical synthesis method.

专利号:US-12264143-B2
优先权日:2020-12-17
标 题:Synthesis of cannabinoids and cannabinoid precursors, and related compounds, formulations, and methods of use
发明人：SAMMIS GLENN M; ROGGEN MARKUS
权利人:NALU BIO INC
摘要:Methods are provided for the synthesis of cannabinoids, including cannabidiol (CBD), cannabinol (CBN), cannabichromene (CBC), cannabidiolic acid (CBDA), cannabigerol (CBG), cannabigerolic acid (CBGA), cannabidivarin (CBDV), cannabidibutol (CBD-C4), dihydrocannabidiol (DCBD), tetrahydrocannabivarin (THCV), analogs thereof, and precursors to the foregoing. One method employs phloroglucinol or a phloroglucinol analog as a starting material. The syntheses are stereospecific, efficient, selective, and cost-effective, with little or no potential for generation of THC ((−)-trans-Δ9-tetrahydro-cannabinol) or any other psychoactive side product. Telescoped syntheses are also provided, as are new cannabinoids, pharmaceutical formulations, and methods of use.