专利号:US-2013150622-A1 优先权日:2011-12-12 标题:Stereoselective synthesis of tapentadol and its salts 发明人:FANDRICK DANIEL ROBERT; RODRIGUEZ SONIA; YANG BING-SHIOU 权利人:BOEHRINGER INGELHEIM INT; BOEHRINGER INGELHEIM INT 摘要:A process for the synthesis of a salt of tapentadol.
专利号:WO-9507882-A1 优先权日:1993-09-14 标 题:Synthesis of amido acids from carboxylic acid esters and amino acid salts 发明人:HEINZMAN STEPHEN WAYNE; DUPONT JEFFREY SCOTT 权利人:PROCTER & GAMBLE 摘要:Chemical synthesis of amido acids, and their conversion to amido acid phenyl ester sulfonates for use as bleach activators, starting from carboxylic acid esters and amino acid salts.
专利号:WO-2024018354-A1 优先权日:2022-07-18 标题 :A process for the synthesis of 4-alkoxy-3-hydroxypicolinic acids and intermediates thereof 发明人:MAL SANJIB; SARKAR PARANTAP; PATRA PRANAB KUMAR; KLAUSENER ALEXANDER GUENTHER MARIA 权利人:PI INDUSTRIES LTD 摘要:The present invention discloses a process for the synthesis of 4- alkoxy-3-hydroxypicolinic acids of formula (I) from 2-picolinic acid. The present invention further discloses a process for preparation of compounds of formula (iii) from compounds of formula (ii). The present invention also discloses novel intermediate compounds of formula (iii).
专利号:US-5534642-A 优先权日:1993-09-14 标题 :Synthesis of amido acids from carboxylic acids and lactams 发明人:HEINZMAN STEPHEN W; DUPONT JEFFREY S; TETTENHORST WILLIAM C 权利人:PROCTER & GAMBLE 摘要:Chemical synthesis of amido acids, and their conversion to amido acid phenyl ester sulfates for use as bleach activators, starting from carboxylic acids and lactams.
专利号:US-8192762-B2 优先权日:2005-06-01 标题 :Preparation of soluble and colloidal molecularly imprinted polymers by living polymerization 发明人:KARIM KHALKU; PILETSKY SERGEY ANATOLIYOVICH; PILETSKA OLENA VOLODIMIRIVNA; TURNER ANTHONY PETER FRANCIS; CHIANELLA IVA; GUERRIERO ANTONIO RICARDO LEONARDO 权利人:KARIM KHALKU; PILETSKY SERGEY ANATOLIYOVICH; PILETSKA OLENA VOLODIMIRIVNA; TURNER ANTHONY PETER FRANCIS; CHIANELLA IVA; GUERRIERO ANTONIO RICARDO LEONARDO; UNIV CRANFIELD 摘要:The present invention describes a method for synthesis of relatively low molecular weight imprinted polymers using living polymerization, and their application in analytical chemistry, pharmacology, medicine and the food industry. Specifically the low-molecular weight polymers are synthesized by the polymerization of functional monomers in the presence of a template, such as a biological receptor, enzyme, nucleic acid, cell, virus, microorganism, tissue sample or drug using living initiator. The conditions of living polymerization ensure a relatively small size of synthesized molecules. Synthesized in this way molecules (dimers, oligomers, polymers, or their mixture) have a higher affinity to the template than the original monomers and can rebind it in vitro and/or in vivo. As a further aspect of the present invention, polymers synthesized as described above can be used as drugs in pharmacology and medicine, as receptor-specific ligands in analytical chemistry (sensors, assays), and for separations in the biotechnology, pharmaceutical and food industries.
专利号:US-4041068-A 优先权日:1976-06-29 标题:Synthesis of oxalate esters by catalytic oxidative carbonylation of borate esters 发明人:ZEHNER LEE R; ZAJACEK JOHN G 权利人:ATLANTIC RICHFIELD CO 摘要:A process for the preparation of oxalate esters by the catalytic oxidative carbonylation of orthoborate, metaborate and polyborate esters or mixtures thereof with carbon monoxide and oxygen or an oxygen-containing gas in the presence of a metal salt catalyst, an amine base and at least a catalytic amount of an alcohol. Preferably a catalytic amount of particular metal oxidizing salts are employed along with a catalytic amount of an amine salt compound which may be formed in situ by the addition of an acid. Alternatively various counterions and ligands of the metal salt catalysts may be employed.
参考标题:Stereocontrolled Construction Of Tetrasubstituted Tetrahydrofurans: Synthesis Of 2,5-Anhydro D-Glucitol 作者:Biswanath Das,Duddukuri Nandan Kumar |发布日期:2010.11 摘要:A Highly Stereoselective Construction Of 2,3,4,5-Tetrasubstituted Tetrahydrofurans Has Been Accomplished By An Unusual Intramolecular 5-Endo-Tet Cyclization Of 2,3-Epoxy Alcohols Involving Hydroxyl Nucleophile. The Method Has Been Utilized For The Synthesis Of 2,5-Anhydro D-Glucitol Through Two Different Approaches Starting From The Chiral Molecule, L(+)-Diethyl Tartarate Or From The Non-Chiral Compound
合成参考文献
摘要:Aggarwal, V. K.; McGarrigle, E. M.; Shaw, M. A., Science of Synthesis: Stereoselective Synthesis, (2011) 2, 339. 摘要:Tauchert, M. E., Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (2013) 1, 313. 摘要:Jana, A.; Małecki, P.; Grela, K., Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis, (2016) 2, 58.