CAS: 13623-11-5; 2,4,5-Trimethylthiazole

相似化合物

74531-15-0 3581-91-7 2279122-45-9

上下游产品

2,4,5-trimethyloxazole 3-thiazoline(E,Z)-4,5-Dihydro-2,4,5-trimethyl-Δ3-thiazoline 5-bromo-2,4-dimethyl-1,3-thiazole methyl iodide3-Benzyl-2,4,5-trimethyl-thiazolium-bromid b]thiazole2,3-dimethyl-6-phenyl-pyrrolo[2,1-b]thiazole b]thiazole6-(4-bromo-phenyl)-2,3-dimethyl-pyrrolo[2,1-b]thiazole b]thiazole6-(4-methoxy-phenyl)-2,3-dimethyl-pyrrolo[2,1-b]thiazole

(2,4-二甲基-1,3-噻唑-5-基)乙酸 反应生成2,4,5-三甲基噻唑
参考文献:263.将蔗糖转化为噻唑衍生物.第二部分 2:4-二甲基噻唑衍生物和2:4:5-三甲基噻唑
标题:263.将蔗糖转化为噻唑衍生物.第二部分 2:4-二甲基噻唑衍生物和2:4:5-三甲基噻唑
摘要:
Doi:10.1039/jr9470001400

专利信息

专利号:US-11020399-B2
优先权日:2011-05-04
标 题:Intermediates useful in the synthesis of compounds as modulators of protein kinases

专利号:US-6852744-B2
优先权日:2000-08-30
标题:Pyrrolidine derivatives and their use as chymase inhibitor
发明人：DEGUCHI TAKASHI; SHIRATAKE RYOTARO; SATO FUMINORI; FUJITANI BUICHI; HONDA YAYOI; KIYOSHI AKIHIKO; NOTAKE MITSUE; SHOWELL GRAHAM ANDREW; BOYLE ROBERT GEORGE; KLAIR SUKHBINDER SINGH
权利人:DAINIPPON PHARMACEUTICAL CO
摘要:Novel pyrrolidine derivatives, being useful as chymase inhibitor or intermediate for synthesis of the active compounds, which has the formula (I): wherein R<1 >is cycloalkyl, substituted or unsubstituted phenyl or naphthyl, indanyl, thienyl, furyl, substituted or unsubstituted indolyl, benzofuryl, substituted or unsubstituted benzothienyl, etc.; R<2 >is H, alkyl, phenyl-lower alkyl, cycloalkyl or cycloalkyl-lower alkyl; R<3 >is (i) substituted or unsubstituted monocyclic heterocyclic group, (ii) substituted or unsubstituted benzene- or pyridine-fused heterocyclic group, or (iii) a group (a): R<4 >and R<5 >are independently H or OH, but R<4 >and R<5 >are not simultaneously H, or both form oxo; n is 0, 1, 2 or 3; or a salt thereof.

专利号:WO-2014024119-A1
优先权日:2012-08-06
标 题:Heterocyclic amides as itk inhibitors
发明人：KUMAR SUKEERTHI; THOMAS ABRAHAM; CHIKHALE RAJENDRA PRAKASH; WAGHMARE NAYAN TATERAO; KADLAG NANASAHEB; KHAIRATKAR-JOSHI NEELIMA; SHAH DAISY MANISH
权利人:GLENMARK PHARMACEUTICALS SA
摘要:The present invention is directed to heterocyclic amide compounds of formula (I) as Tec kinase inhibitors, in particular ITK (interleukin-2 inducible tyrosine kinase) inhibitors. Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders mediated by ITK.