CAS: 493038-93-0; 2-(3-Chloro-5-Fluorophenyl)Acetonitrile

上下游产品

CAS号773837-37-9 sodium cyanide | CAS号493024-39-8 3-氯-5-氟苄基溴

Sodium Cyanide,3-氯-5-氟溴苄置于苄基三丁基氯化铵,溶剂黄146体系中,用 水,甲苯 作为反应溶剂,化学反应 4.0H,以100%的收率获得产物3-氯-5-氟苯乙腈
参考文献:Thiazole Derivative
标题:Thiazole Derivative
摘要:提供了一种对gpr52具有激动剂作用的化合物,该化合物可作为预防或治疗精神疾病如精神分裂症等的药物.一种由以下通式(i)表示的化合物:其中各个符号的定义如说明书中所述,或其盐形式.

专利信息

专利号:US-11034695-B2
优先权日:2016-09-23
标 题:Dopamine-β-hydroxylase inhibitors
发明人：SOARES DA SILVA PATRÃ?CIO; ROSSI TINO; KISS LASZLO ERNO; BELIAEV ALEXANDER; LEAL PALMA PEDRO NUNO
权利人:BIAL—PORTELA & CA S A; BIAL—PORTELA & Cᵃ S A
摘要:This invention relates to: (a) compounds of Formula Ia (with R1, R4, R5, R6, n and A as defined herein) and pharmaceutically acceptable salts or solvates thereof that are useful as dopamine-β-hydroxylase inhibitors; (b) pharmaceutical compositions comprising such compounds, salts or solvates; (c) the use of such compounds, salts or solvates in therapy; (d) therapeutic methods of treatment using such compounds, salts or solvates; and (e) processes and intermediates useful for the synthesis of such compounds.