专利号:WO-2019018655-A1 优先权日:2017-07-19 标题:SYNTHESIS OF BIOCOMPATIBLE TRITYLE RADICALS FOR APPLICATIONS AS HYPERPOLARIZATION AGENTS 发明人:DRIESSCHAERT BENOIT; KHRAMTSOV VALERY 权利人:UNIV WEST VIRGINIA 摘要:The present invention provides compositions and methods relating to paramagnetic probes for EPR spectroscopy. The present invention provides compositions and methods for biocompatible paramagnetic probes that can be targeted to a target in vitro or in vivo, and can provide a monofunctional or multifunctional measurement of a number of physiological parameters of cells or tissue. in vitro or in vivo, individually or in combination. The invention further relates to methods of using the compositions created by the methods of the invention.
专利号:US-2011207114-A1 优先权日:2008-10-29 标题 :Amplified Fluorescence Polymers and Sensor Thereof 发明人:KUMAR ANIL; SINHA JASMINE; PULLELA PHANI KUMAR 权利人:INDIAN INST OF TECHNOLOGY MUMBAI; BIGTEC PRIVATE LTD 摘要:The present disclosure is related to amplified fluorescence polymers (AFPs) with pendant functional groups, their derivatives and their synthesis. The amplified fluorescence polymers can be used in various biological and chemical sensors.
专利号:US-7902376-B2 优先权日:2008-01-23 标 题 :Process for preparing chiral dipeptidyl peptidase-IV inhibitor intermediates 发明人:XU FENG; KIM MARY M; KOHMURA YOSHINORI; SLADICKA TRICIA; ROSEN JONATHAN D; ZACUTO MICHAEL J 权利人:MERCK SHARP & DOHME; BANYU PHARMA CO LTD 摘要:A novel process is provided for the preparation of chiral trans-2,3-disubstituted 5-oxotetrahydropyrans of structural formula (I): n nwherein Ar is optionally substituted phenyl and P is a primary amine protecting group. These compounds are useful in the synthesis of dipeptidyl peptidase-IV inhibitors for the treatment of Type 2 diabetes. Also provided are useful intermediates obtained from the process.
专利号:JP-2008540338-A 优先权日:2005-04-27 标题 :Click chemistry synthesis of molecular imaging probes
专利号:US-6706885-B2 优先权日:2001-06-06 标题:Process for preparing integrin antagonist intermediates 发明人:YASUDA NOBUYOSHI; PALUCKI MICHAEL; XIAO YI; HARTNER FREDERICK W; TAN LUSHI 权利人:MERCK & CO INC 摘要:A novel process is provided for the preparation of optionally protected 2,5-di-(3'-aminopropyl)-pyridines which are useful in the synthesis of alphav integrin receptor antagonists. Also provided are useful intermediates obtained from the process.
专利号:CN-118459756-A 优先权日:2024-05-07 标 题 :Temperature-sensitive material, glycoconjugate, synthesis method thereof and application of glycoconjugate in sugar solid phase synthesis
[参考文献]: Yuji Odagaki, Et Al. Functional Activation Of G-Proteins Coupled With Muscarinic Acetylcholine Receptors In Rat Brain Membranes. J Pharmacol Sci. 2014;125(2):157-68.
合成参考文献
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