CAS: 67515-76-8; Methyl 5-Aminopicolinate

相似化合物

131052-40-9 24242-20-4 29682-14-2

上下游产品

CAS号29682-14-2 5-硝基吡啶甲酸甲酯 | CAS号67-56-1 甲醇 | CAS号24242-20-4 5-氨基吡啶-2-羧酸 | CAS号107504-07-4 5-氟吡啶甲酸甲酯 | CAS号872355-60-7 METHYL 5-AMINO-... | CAS号873651-92-4 2-(羟甲基)-5-氨基吡啶 | CAS号797060-52-7 5-氨基-6-溴吡啶-2-甲酸甲酯

5-氨基-2-吡啶羧酸置于三甲基硅烷化重氮甲烷体系中,用 甲醇,乙醚,苯 作为反应溶剂,化学反应 6.0H,反应生成 5-氨基吡啶-2-甲酸甲酯
参考文献: 2-Heteroarylamino-Pyrimidine Derivatives As Kinase Inhibitors[fr] Dérivés De 2-Hétéroarylamino-Pyrimidine En Tant Qu'Inhibiteurs De Kinase
标题: 2-Heteroarylamino-Pyrimidine Derivatives As Kinase Inhibitors[fr] Dérivés De 2-Hétéroarylamino-Pyrimidine En Tant Qu'Inhibiteurs De Kinase
摘要:该发明提供了式(i)的化合物及其药物组合物,这些化合物可用作蛋白激酶抑制剂,以及使用这些化合物治疗,改善或预防与异常或失调激酶活性相关的疾病的方法.在某些实施例中,该发明提供了使用这些化合物治疗,改善或预防涉及c-Kit,Pdgfrα,Pdgfrβ,Csf1R,Abl,Bcr-Abl,Csk,Jnk1,Jnk2,P38,P70S6K,Tgfβ,Src,Egfr,Trkb,Fgfr3,Fes,Lck,Syk,Raf,Mkk4,Mkk6,Sapk2β,Brk,Fms,Kdr,C-Raf或b-Raf激酶异常激活的疾病或紊乱的方法.

专利信息

专利号:CN-104693241-A
优先权日:2015-03-02
标 题 :'One-pot method' synthesis of minodronic acid intermediate and method for preparing minodronic acid

专利号:US-9700543-B2
优先权日:2011-05-31
标题 :GLP-1 receptor stabilizers and modulators
发明人：BOEHM MARCUS F; MARTINBOROUGH ESTHER; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; FOWLER THOMAS; NOVAK ANDREW; MEGHANI PREMJI; BRAHMACHARY ENUGURTHI; YEAGER ADAM RICHARD
权利人:CELGENE INT II SÀRL
摘要:Compounds that bind the glucagon-like peptide 1 (GLP-1) receptor, methods of their synthesis, methods of their therapeutic and/or prophylactic use, and methods of their use in stabilizing GLP-1 receptor in vitro for crystallization of the GLP-1 receptor are provided. Certain compounds may have activity as modulators or potentiators with respect to glucagon receptor, GIP receptor, GLP-1 and GLP-2 receptors, and PTH receptor on their own or in the presence of receptor ligands such as GIP(1-42), PTH(1-34), Glucagon(1-29), GLP-2(1-33), GLP-1(7-36), GLP-1(9-36), oxyntomodulin and exendin variants.

专利号:IT-8224576-A1
优先权日:1982-12-03
标题 :New derivatives of aminopyridincarboxylic acids, their synthesis methods and pharmaceutical compositions containing them