CAS: 21906-31-0; 1-(2-Bromophenyl)Propan-2-One

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2-bromo-β-methyl-β-nitrostyrene 2-bromophenylacetyl chloride dimethylcadmium bromobenzene (d,l)-2-methoxyamphetamine methyl-(1-(ortho-bromophenyl)ethyl)-ketone 1-[2-(phenylethynyl)phenyl]-2-propanone 2-(6-methoxy-2-naphthyl)phenylacetone

邻溴氰苄置于硫酸,Sodium Hydride体系中,用 四氢呋喃,1,4-二氧六环,Mineral Oil 用作溶剂,化学反应 58.5H,反应生成2-溴苯基丙酮
参考文献:[1,5]-烷硫基基团转移介导的骨骼重排构建1,3-二硫代四联蛋白.
标题:[1,5]-烷硫基基团转移介导的骨骼重排构建1,3-二硫代四联蛋白.
摘要:描述了涉及[1,5]-烷硫基转移/环化序列的新型骨架重排.用催化量的sc(otf)3处理在均苄基位置具有硫缩酮部分的亚苄基丙二酸酯,以非常好的化学收率得到了烷硫基重排的加合物.对反应机理的详细研究表明,分子内共轭物的添加/开环顺序(不是通过空间转移)是实现该反应的关键.
Doi:10.1021/acs.Orglett.8B01610

专利信息

专利号:US-4742084-A
优先权日:1983-11-21
标 题 :Aralykyl (arylethynyl)aralkyl amines and their use as vasodilators and antihypertensives
发明人：CARSON JOHN R
权利人:MCNEILAB INC
摘要:Acetylenes of the formula (I): (I) wherein Y, m, R1, R2, q, Alk, R3 n and R4 are as defined herein and Ar1 and Ar2 are aromatic, including the salts and ammonium derivatives of formula (I), in treating angina, hypertension and cardiac arrhythmias. Pharmaceutical compositions, methods of use and synthesis and novel intermediates are also part of the invention.

专利号:US-4661635-A
优先权日:1983-11-21
标题 :Aralykyl (arylethynyl)aralkyl amines and their use as vasodilators and antihypertensives
发明人：CARSON JOHN R
权利人:MCNEILAB INC
摘要:Acetylenes of the formula (I): (I) wherein Y, m, R1, R2+L, q, Alk, R3, n and R4 are as defined herein and Ar1 and Ar2 are aromatic, including the salts and ammonium derivatives of formula (I), in treating angina, hypertension and cardiac arrhythmias. Pharmaceutical compositions, methods of use and synthesis and novel intermediates are also part of the invention.

专利号:CN-117126044-A
优先权日:2023-04-12
标 题 :A microwave-assisted synthesis method of methyl ketone compounds

专利号:CN-117126044-B
优先权日:2023-04-12
标题 :Microwave-assisted synthesis method of methyl ketone compound

专利号:CN-104710256-A
优先权日:2015-01-22
标 题:Cheap and efficient synthesis method of alpha-hydroxyketone compound