CAS: 53087-13-1; 1-(Benzyloxy)-3-Bromobenzene

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CAS号591-20-8 3-溴苯酚 | CAS号100-44-7 氯化苄 | CAS号100-39-0 溴化苄 | CAS号585-79-5 间溴硝基苯 | CAS号100-51-6 苯甲醇 | CAS号584-08-7 碳酸钾 | CAS号34068-01-4 3-苄氧基苯乙酮 | CAS号946-80-5 苄基苯基醚 | CAS号72216-35-4 3-(苄氧基)氟苯 | CAS号26926-56-7 4-(3-phenylmeth... | CAS号765908-38-1 3-(苄氧基)苯硼酸频那醇酯 | CAS号591-20-8 3-溴苯酚 | CAS号320727-36-4 α-甲基-(3-苄氧基)苄醇 | CAS号1484-26-0 3-苄氧基苯胺 | CAS号156682-54-1 3-苄氧基苯硼酸 | CAS号893736-89-5 3'-(BENZYLOXY)[...

间溴苯酚,氯化苄置于potassium Carbonate体系中,用 丁酮 作为反应溶剂,化学反应 16.0H,以93%的收率获得产物3-苄氧基溴苯
参考文献:The Dramatic Influence Of The Location Of Bend And Of Lateral Fluoro Substitution On The Mesomorphic Properties Of Angular Chiral Esters Based On A 1,3-Disubstituted Benzene Ring
标题:The Dramatic Influence Of The Location Of Bend And Of Lateral Fluoro Substitution On The Mesomorphic Properties Of Angular Chiral Esters Based On A 1,3-Disubstituted Benzene Ring
摘要:本文详细描述了一系列基于1,3-二取代苯单元的3环和4环手性酯的合成及其介态特性.这些材料都偏离了液晶的常规线性分子结构,因此具有角度特性.其中一些材料的弯曲位于分子末端,链条偏离正常线性排列,因此可以准确描述为"曲棍球棒"分子结构.其他材料则具有真正的弯曲核结构,弯曲指向分子的中心,因此最好称为"回旋镖"形状.在所有情况下,各种角度材料之间以及与其线性类似物之间的介相形态和转变温度进行了有趣的比较.特别是,在新型角态材料中,侧向氟 Substituion 对转变温度的影响与已知线性类似物中的结果有显著不同.该研究工作是一个更大正在进行的研究项目的一部分,旨在探讨角液晶的介态和手性依赖特性.研究表明,当弯曲靠近分子的中心时,母体化合物中不可能出现介态.然而,这类化合物的侧向氟替代促进了液晶相的反应生成.当分子的弯曲是由于核心末端的末端单元引起时,则意外地得到了高清晰度点,同时这种材料显示出高倾斜角的潜力,以及强烈的螺旋介相倾向.对这些后者例子的侧向氟替代一致性地导致了明显更高的清晰度点,这与已知线性分子结构液晶中报告的行为形成了鲜明对比.
DOI:10.1039/b923267B

专利信息

专利号:WO-2025093057-A1
优先权日:2023-11-02
标题:Method for preparing metaraminol bitartrate
发明人：ZHAO TAOTAO; SHANG KUN; YANG SHIHONG; LI TIANQING; ZOU PENG; ZHANG QI
权利人:WUHAN WUYAO PHARMACEUTICAL CO LTD
摘要:The present disclosure belongs to the technical field of drug synthesis, and specifically relates to a method for preparing metaraminol bitartrate. The preparation method comprises the following steps: using benzyloxycarbonyl-L-alanine as a raw material, reacting same with dimethylhydroxylamine hydrochloride, and then reacting with 3-benzyloxybromobenzene, then performing a one-step hydrogenation reaction to obtain metaraminol, and finally forming a salt to obtain metaraminol bitartrate.

专利号:RU-2167148-C2
优先权日:1995-12-20
标题 :1-phenyl-2-dimethylaminomethylcyclohexane-1-ol compounds, methods of their synthesis and drug based on thereof

专利号:CN-119504454-A
优先权日:2024-11-21
标题:Synthesis process of meta-hydroxylamine bitartrate

专利号:RU-2178409-C2
优先权日:1995-07-11
标 题 :6-dimethylaminomethyl-1-phenylcyclohexane compounds as pharmaceutically active substances and method of their synthesis (variants)