CAS: 540-38-5; 4-Iodophenol

上下游产品

CAS号5122-99-6 4-碘苯硼酸 | CAS号123-30-8 对氨基苯酚 | CAS号13997-71-2 1-iodo-4-prop-2... | CAS号108-95-2 苯酚 | CAS号39735-76-7 1-iodo-4-prop-2... | CAS号109586-39-2 4-碘苯基三氟甲磺酸酯 | CAS号99522-34-6 2-(4-iodophenox... | CAS号33527-94-5 4-碘乙酰基苯酚 | CAS号106-41-2 对溴苯酚 | CAS号122-79-2 乙酸苯酯 | CAS号103808-68-0 4-碘-[2-(1-哌啶基)乙氧基l]苯 | CAS号10009-44-6 (2R)-2-(4-iodop... | CAS号324-94-7 4-氟-4'-羟基联苯 | CAS号398-23-2 4,4'-二氟联苯 | CAS号321-62-0 2'-Fluoro-4-bip... | CAS号64465-61-8 4-(3-氟苯基)苯酚 | CAS号3943-97-3 4-羟基肉桂酸甲酯 | CAS号5068-21-3 (4-羟基苯基)二苯基膦 | CAS号32604-29-8 4,4'-二乙酰氧基联苯 | CAS号4377-41-7 2-(氯甲基)喹啉

对碘苯胺置于uranyl Nirate Hexahydrate,水,三氟乙酸体系中,化学反应 36.0H,以93%的收率获得产物4-碘苯酚
参考文献:一种芳基酚类化合物及其合成方法和应用
标题:一种芳基酚类化合物及其合成方法和应用
摘要:本发明公开了一种式(3)芳基酚类化合物的合成方法.所有体系在空气或者氮气氛围中进行,利用可见光激发光敏剂催化.在反应溶剂中,以式(1)Arnr1R2和式(2)水为反应原料,在酸的辅助作用下,反应得到式(3)芳基酚类化合物.本发明式(1)Arnr1R2可以是一级胺,三级胺,也可以是甾体,氨基酸类衍生物,还可以是丙泊酚,扑热息痛,布洛芬,奥沙普秦,吲哚美辛类等药物或者衍生物.本发明合成方法原料廉价易得,反应操作简单,反应条件温和,反应收率较高,底物官能团兼容性好.本发明流体反应不仅可以实现基础化工品的放大,还可以实现精细化工品的放大,如药物丙泊酚,扑热息痛的合成.本发明具有广泛的应用前景和使用价值.

专利信息

专利号:US-10005720-B2
优先权日:2013-04-05
标题:Compounds useful for the treatment of metabolic disorders and synthesis of the same
发明人：SEXTON JONATHAN Z; BRENMAN JAY E; MUSSO DAVID L
权利人:NORTH CAROLINA CENTRAL UNIV; UNIV NORTH CAROLINA CHAPEL HILL
摘要:The present invention provides compounds of Formula (I): wherein variables X, Y, Z and R1 are as described herein. Some of the compounds described herein are glutamate dehydrogenase activators. The invention is also directed to pharmaceutical compositions comprising these compounds, uses of these compounds and compositions in the treatment of metabolic disorders as well as synthesis of the compounds.

专利号:US-2015239796-A1
优先权日:2014-02-19
标题:One pot synthesis of 18f labeledtrifluoromethylated compounds with difluoro(iodo)methane
发明人：RüHL THOMAS; RISS PATRICK; RAFIQUE WAQAS
权利人:UNIV OSLO
摘要:The present invention relates to compositions and methods for the synthesis of 18 F labeled compounds. In particular, the present invention relates to a copper (I) mediated one pot method for 18 F-trifluoromethylation of aromatic- or heteroaromatic halides with difluoro(iodo)methane (e.g., for use at PET imaging agents).

专利号:US-9273023-B2
优先权日:2011-11-01
标 题:Modular synthesis of graphene nanoribbons and graphene substructures from oligo-alkynes
发明人：ALABUGIN IGOR; BYERS PHILIP M
权利人:UNIV FLORIDA STATE RES FOUND
摘要:A method for the synthesis of carbon-based structures, particularly graphene substructures and ribbons, from oligo- and poly-alkyne starting materials.

专利号:US-2006287529-A1
优先权日:2003-02-20
标 题:Solid phase synthesis of antitumoral compounds
发明人：ALVAREZ MERCEDES; ALBERICIO FERNANDO; CIRONI PABLO; CUE VAS CARMEN; FRANCESCH ANDREAS; MARFIL MARTA
权利人:ALVAREZ MERCEDES; ALBERICIO FERNANDO; CIRONI PABLO; CUE VAS CARMEN; FRANCESCH ANDREAS; MARFIL MARTA
摘要:Lamellarins are prepared using a solid phase synthesis. In a first aspect, the process includes a step as follows: Formula (I) where R 1 to R 15 are as defined, and X is halogen, provided that one of R 2 , R 3 or R 4 is immobilised to a resin. In a second aspect, the process includes a step as follows: Formula (II) where R 1 ′ to R 5 ′, R 11 ′ and R 13 ′ are as defined, X 1 and X 2 are halogen, M is a metal function and PG is an amino protecting group, provided that one of that R 2 ′, R 3 ′ or R 4 ′ is immobilised to a resin.

专利号:EP-1641729-B1
优先权日:2003-07-09
标题:Use of functionalized onium salts as a soluble support for organic synthesis
发明人：VAULTIER MICHEL; GMOUH SAID; HASSINE FATIMA
权利人:CENTRE NAT RECH SCIENT; UNIV RENNES
摘要:The invention relates to the use of a onium salt functionalized by at least one organic function, as a soluble support, in the presence of at least one organic solvent, for organic synthesis of a molecule, in a homogenous phase, by at least one transformation of said organic function. The onium salt enables the synthesized molecule to be released. The onium salt is present in liquid or solid form at room temperature and corresponds to formula A₁⁺, X₁^-, wherein A₁⁺ represents a cation and X₁^- represents an anion.

专利号:US-2024424116-A1
优先权日:2023-06-16
标题:Pegylated-AU(III) Reagents for Rapid Cysteine S-Arylation of Biomolecules
发明人：MAYNARD HEATHER D; SPOKOYNY ALEXANDER; AYTAC HAYDEN MONTGOMERY; MESSINA MARCO; DOUD EVAN
权利人:UNIV CALIFORNIA
摘要:Compositions and methods for cysteine arylation of polypeptides using Au(III) organometallic complexes are disclosed herein. The bioconjugation reactions proceed rapidly at ambient temperature in various buffers. The compositions and methods enable the synthesis of PEGylated polypeptide conjugates with selectivity and high efficiency, allowing facile modification of complex biomolecules.