CAS: 27655-40-9; Isoquinoline-5-Sulfonic Acid

上下游产品

CAS号105627-79-0 异喹啉-5-磺酰氯盐酸盐 | CAS号119-65-3 异喹啉 | CAS号7664-93-9 硫酸 | CAS号7732-18-5 水 | CAS号5984-79-2 isoquinoline; h... | CAS号84468-15-5 异喹啉-5-磺酰氯 | CAS号105627-79-0 异喹啉-5-磺酰氯盐酸盐 | CAS号2439-04-5 5-羟基异喹啉 | CAS号116970-50-4 N-(2-氨基乙基)-5-异喹...

异喹啉置于硫酸体系中,用60%的收率获得5-异喹啉磺酸
参考文献:Isoquinolinesulfonyl Derivative As Rho Kinase Inhibitor
标题:Isoquinolinesulfonyl Derivative As Rho Kinase Inhibitor
摘要:本发明公开了一类异喹啉磺酰衍生物作为rho激酶抑制剂,以及其药物组合物,并涉及它们的药用可接受用途.具体而言,本发明涉及如式(I)所示的化合物,或其药用可接受的盐.

专利信息

专利号:US-9982072-B2
优先权日:2013-10-30
标 题 :Synthesis of acetal compounds
发明人：LOCCUFIER JOHAN
权利人:AGFA GRAPHICS NV; AGFA NV
摘要:A process for the preparation of optionally asymmetric acetal compounds includes reacting a compound containing a hydroxyl group with a vinylether compound in the presence of a zwitterionic catalyst including at least one basic nitrogen containing structural fragment and at least one sulfonic acid group in its structure, with the proviso that a molar ratio of the basic nitrogen to sulfonic acid is 1:1.

专利号:US-2016237185-A1
优先权日:2013-10-30
标 题:Synthesis of acetal compounds

专利号:US-2008187575-A1
优先权日:2004-08-27
标题:Pyrimidine Derivatives
发明人：KLEBL BERT; BAUMANN MATTHIAS; HOPPE EDMUND; BREHMER DIRK; DAUB HENRIK; KERI GYORGY; VARGA ZOLTAN; MAROSFALVI JENO; ORFI LASZLO
权利人:KLEBL BERT; BAUMANN MATTHIAS; HOPPE EDMUND; BREHMER DIRK; DAUB HENRIK; KERI GYORGY; VARGA ZOLTAN; MAROSFALVI JENO; ORFI LASZLO
摘要:The present invention relates to pyrimidine derivatives, methods for their synthesis, and the use of said pyrimidine derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of cell proliferation disorders, cancer, leukemia, erectile dysfunction, cardiovascular diseases and disorders, inflammatory diseases, transplant rejection, immunological diseases, neuroimmunological diseases, autoimmune diseases, infective diseases including opportunistic infections, prion diseases and/or neuro-degeneration. Furthermore, the present invention relates to pharmaceutical compositions containing at least one pyrimidine derivative and/or pharmaceutically acceptable salts thereof as an active ingredient together with at least one pharmaceutically acceptable carrier, excipient or diluents as well as to methods for prophylaxis and/or treatment of the above-mentioned diseases and disorders.

专利号:CN-117229213-A
优先权日:2023-08-10
标题:An efficient synthesis method of carbamazepine

专利号:CN-113582926-B
优先权日:2021-09-09
标题:Synthesis method of 4-fluoroisoquinoline-5-sulfonyl chloride or pharmaceutically acceptable salt thereof