CAS: 68291-97-4; Benzo[d]Isoxazol-3-Ylmethanesulfonamide

相似化合物

73101-64-1 1188265-58-8 68291-99-6

上下游产品

CAS号73101-65-2 1,2-苯异噁唑-3-甲烷磺酰氯 | CAS号73101-64-1 1,2-苯并异噁唑-3-甲磺酸钠盐 | CAS号4865-84-3 1,2-苯并异恶唑-3-乙酸 | CAS号73101-64-1 1,2-苯并异噁唑-3-甲磺酸钠盐 | CAS号69-72-7 水杨酸 | CAS号73101-70-9 1,3-benzoxazol-... | CAS号68936-43-6 N-乙酰唑胺 | CAS号49670-47-5 2,2-dioxo-1,2λ6...

1,2-Benzisoxazole-3-Methanesulfonic Acid Sodium Salt置于三乙胺,三氯氧磷,氨体系中,用 1,2-二氯乙烷 作为反应溶剂,化学反应 6.0H,反应生成 唑尼沙胺
参考文献:One-Pot Process For The Preparation Of 1,2-Benzisoxazole-3-Methanesulfonamide
标题:One-Pot Process For The Preparation Of 1,2-Benzisoxazole-3-Methanesulfonamide
摘要:一种制备1,2-苯并异噁唑-3-甲磺酰胺的工艺,不需要固体中间体的分离,使用4-羟基香豆素作为起始化合物,以水和1,2-二氯乙烷作作为反应溶剂;以及一种工业上有用的制备1,2-苯并异噁唑-3-乙酸的工艺,通过在水中反应4-羟基香豆素和羟胺.

专利信息

专利号:US-10022446-B2
优先权日:2014-08-22
标题 :PH responsive hybrid hydrogel and method of synthesis thereof
发明人：KIZILEL SEDA; CEVIK OZLEM
权利人:KOC UENIVERSITESI
摘要:A pH-responsive hybrid hydrogel, namely poly(Methacrylic acid-grafted-Ethylene Glycol) P(MAA-g-EG) cross-linked with Styrene-Butadiene-Styrene (SBS) polymer and photopolymerized by visible light. The resulting polymer turned out to have better integrities, high swelling ratios, pH-responsive and biocompatible character. Also the visible-light-induced synthesis of these pH-responsive composite wherein eosin Y is used as photoinitiator and triethanolamine is used as a co-initiator is also disclosed in the invention.

专利号:WO-2016028237-A1
优先权日:2014-08-22
标题 :A novel ph responsive hydrogel and method of synthesis
发明人：KIZILEL SEDA; CEVIK OZLEM
权利人:KOÇ ÃœNIVERSITESI
摘要:A pH-responsive hydrogel, namely poly(Methacrylic acid-grafted-Ethylene Glycol) P(MAA-g-EG), that is synthesized via photopolymerization that is initiated by visible light with enhanced swelling properties as compared to P(MAA-g-EG) hydrogel that is synthesized through UV-light initiated photopolymerization technique. Also the method of synthesis of the said hydrogel and the use of the hydrogel in pharmacy for drug delivery applications.

专利号:US-7745471-B2
优先权日:2004-06-18
标题:Derivatives of 1,2-benzisoxazole-3-methane sulfonic acid as novel intermediates for the synthesis of zonisamide
发明人：NADDAKA VLADIMIR; KLOPFER EYAL; SAEED SHADY; ARAD ODED; KASPI JOSEPH
权利人:CHEMAGIS LTD
摘要:Derivatives of 1,2-benzisoxazole-3-methanesulfonic acid, which are non-hygroscopic and non-hydrated and their use as intermediates from the preparation of zonisamide are disclosed. Further disclosed are processes of preparing zonisamide from these 1,2-benzisoxazole-3-methanesulfonic acid derivatives, processes of preparing exemplary 1,2-benzisoxazole-3-methanesulfonic acid derivatives and crystalline forms of exemplary 2-benzisoxazole-3-methanesulfonic acid derivatives. A novel process of preparing zonisamide is also disclosed.

专利号:US-2008214827-A1
优先权日:2004-02-03
标 题:Synthesis of Cyanoimino-Benzoimidazoles
发明人：GOEHRING R RICHARD; WHITEHEAD JOHN; SHAO BIN
权利人:EURO CELTIQUE SA
摘要:Disclosed in certain embodiments is a process for synthesizing a compound of formula (V) and salts thereof.

专利号:US-2006009644-A1
优先权日:2004-06-18
标 题:Novel crystalline forms of sodium 1,2-benzisoxazole-3-methanesulfonate, processes of preparing same and use thereof in the synthesis of zonisamide
发明人：NADDAKA VLADIMIR; ADIN ITAI; KLOPFER EYAL; ARAD ODED; KASPI JOSEPH
权利人:NADDAKA VLADIMIR; ADIN ITAI; KLOPFER EYAL; ARAD ODED; KASPI JOSEPH
摘要:Disclosed is a process of preparing 1,2-benzisoxazole-3-methanesulfonamide (zonisamide). Also disclosed is a method of dehydrating sodium 1,2-benzisoxazole-3-methanesulfonate, a compound useful in the preparation of 1,2-bisoxazole-3-methanesulfonamide (zonisamide) as well as new crystalline forms of sodium 1,2-benzisoxazole-3-methanesulfonate.

专利号:US-12201669-B2
优先权日:2021-03-11
标 题:Small molecule suppressors of APOE gene expression and cerebral vascular amyloid pathology
发明人：TSAI LI-HUEI; BLANCHARD JOEL
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The present disclosure provides methods of inhibiting amyloid synthesis in a subject using small molecule inhibitors. The invention also includes methods of treating disease associated with amyloid synthesis, such as Alzheimer's disease. The small molecule inhibitors disclosed herein are compounds which are non-immunosuppressant cyclosporin including the pharmaceutically acceptable salts thereof.