CAS: 79538-20-8; 3,5-Difluorobenzyl Alcohol

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CAS号32085-88-4 3,5-二氟苯甲醛 | CAS号32085-88-4 3,5-二氟苯甲醛 | CAS号141776-91-2 3,5-二氟苄溴 | CAS号90390-28-6 N-(3,5-Difluoro...

3,5-二氟苯甲酸置于硼烷四氢呋喃络合物体系中,用 四氢呋喃 作为反应溶剂,化学反应 2.0H,以94.3%的收率获得产物3,5-二氟苄醇
参考文献:N-(取代磺酰基)苯甲酰胺类衍生物及其制备方法和医药用途
标题:N-(取代磺酰基)苯甲酰胺类衍生物及其制备方法和医药用途
摘要:本发明涉及n‑(取代磺酰基)苯甲酰胺类衍生物及其制备方法和医药用途.具体而言,本发明涉及一种通式(I)所示的n‑(取代磺酰基)苯甲酰胺类衍生物,其制备方法及其可药用的盐,以及它们作为治疗剂,特别是作为nav1.7抑制剂的用途,其中通式(I)中的各取代基的定义与说明书中的定义相同.

专利信息

专利号:US-10040752-B2
优先权日:2015-08-24
标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof
发明人：MKRTCHYAN GNEL; YAO QINGWEI
权利人:CODY LABORATORIES INC
摘要:Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

专利号:US-2019002394-A1
优先权日:2015-08-24
标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof

专利号:CN-111303179-A
优先权日:2020-03-17
标 题:Synthesis of a Class of Norcantharidin Carboxylic Acid Difluorobenzyl Esters and Its Antitumor Application

专利号:US-2017057909-A1
优先权日:2015-08-24
标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof

专利号:EP-3341354-A1
优先权日:2015-08-24
标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof

专利号:CN-111303179-B
优先权日:2020-03-17
标 题 :Synthesis of norcantharidin carboxylic acid difluoro benzyl ester and anti-tumor application thereof