CAS: 103-05-9; 2-Methyl-4-Phenyl-2-Butanol

该化合物是第三级酒精,分子配方为C11H16O,其特征为一个联苯组,附在分碳链上,该化合物在有机合成中用作中间体,特别是在香气,药品和特殊化学品的生产中使用,其结构具有稳定性和回活动性,适合各种通灵和凝聚反应.第三级酒精功能增强了其在创造复杂的分子结构中的效用.在普通有机溶剂中具有中等的挥发性和溶性,2-苯乙基-2-丙醇是实验室和工业应用中的多种试剂,其定义明确的化学特性确保合成工艺的性能.

结构式图片

相似化合物

2344-70-9 39516-03-5 22148-86-3

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

1,2-Dimethyl-3-Phenylpropylhydroperoxid 34586-02-2
2-Methyl-2-Phenethyloxirane
(3-(Methoxymethoxy)-3-Methylbutyl)Benzene 223930-74-3
Rac-3-甲基-1-苯基丁烷-1,3-二醇 (±)-1-Methyl-4-Phenylbutane-2,4-Diol 104174-42-7
1,1-二甲基-3-苯基丙醇乙酸酯 2-Methyl-4-Phenylbutan-2-Yl Acetate 103-07-1
1-苯基-3-甲基-3-羟基-1-丁酮 3-Hydroxy-3-Methyl-1-Phenyl-1-Butanone 43108-74-3
Benzyl 1,1-Dimethyl-3-Phenylpropyl Ether
3-苯基丙酸 3-Phenylpropionic Acid 501-52-0 2-Amino-1-Phenyl-3-Methylbutane 46114-16-3 4-Phenyl-2-Butanone 2550-26-7

合成工艺路线路线简述

  • 合成目标产物 2-Methyl-4-Phenyl-2-Butanol 主要起始原料 Benzylacetone And Methylmagnesium Chloride
  • (文献来源)合成步骤主要原料 Benzylacetone 和 Methylmagnesium Chloride
2-Methyl-2-Phenethyloxirane置于palladium On Activated Charcoal 甲酸铵体系中,用 乙醇 用作溶剂,化学反应 5.0H,以90%的收率获得2-甲基-4-苯基-2-丁醇
参考文献:Palladium Catalyzed,Regioselective Reduction Of 1,2-Epoxides By Ammonium Formate
标题:Palladium Catalyzed,Regioselective Reduction Of 1,2-Epoxides By Ammonium Formate
摘要:
Doi:10.1021/jo00120A042

海关参考信息

专利信息


专利号:US-2010240923-A1
优先权日:2007-11-29
标题:Enzymatic synthesis of (meth)acrylic esters of hydroxy-functional aromas
发明人:HAERING DIETMAR; WINTER GABI; SCHNELLER ARNOLD; AULENTA FRANCESCA
权利人:BASF SE
摘要:A process for preparing (meth)acrylic esters (F) of hydroxy-functional aromas (A), in which at least one hydroxy-functional aroma (A) in the presence of at least one enzyme (E) is esterified with (meth)acrylic acid (S), or transesterified with at least one (meth)acrylic ester (D), the reaction in the case of the transesterification being effected in the absence of solvents.

专利号:US-6239146-B1
优先权日:1998-06-02
标 题:Neurotrophic difluoroamide agents
发明人:VRUDHULA VIVEKANANDA M; DUBOWCHIK GENE M; DASGUPTA BIRESHWAR; VYAS DOLATRAI M
权利人:BRISTOL MYERS SQUIBB CO
摘要:The present invention relates to the design, synthesis, and the peptidyl-prolyl isomerase (PPIase or rotamase) inhibitory activity of novel alpha,alpha-difluoroacetamido compounds that are neurotrophic agents (i.e. compounds capable of stimulating growth or proliferation of nervous tissue) and that bind to immunophilins such as FKBP12 and inhibit their rotamase activity. This invention also relates to pharmaceutical compositions comprising these compounds.

专利号:US-10647942-B2
优先权日:2016-12-22
标题:Fragrance and flavor materials
发明人:BLANDINO MAUREEN; LANKIN MICHAEL E
权利人:TAKASAGO PERFUMERY CO LTD
摘要:The present disclosure is directed to the synthesis and application of undecavertol derivatives having unique and desired flavor and/or fragrant characteristics. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The present disclosure is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions.

专利号:US-12114681-B2
优先权日:2018-06-04
标题:Fragrance and flavor materials
发明人:BLANDINO MAUREEN; TANUMA KENJI
权利人:TAKASAGO PERFUMERY CO LTD
摘要:The synthesis and application of compounds having unique and desired flavor and/or fragrance characteristics are provided herein. The compounds herein can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The application is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions.

专利号:US-2021198229-A1
优先权日:2018-03-08
标 题 :Fragrance and flavor materials from 1-(2-hydroxy-4-methylcyclohexyl)-ethanone
发明人:DICKERSON THALIA S; LOMBARDO LOUIS J; LANKIN MICHAEL E
权利人:TAKASAGO PERFUMERY CO LTD
摘要:The present disclosure is directed to 1-(2-hydroxy-4-methycyclohexyl)-ethanone derivatives having unique and desired flavor and/or fragrance characteristics, as well as the synthesis and application of the derivatives. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor ingredients to modify or enhance already existing fragrance compositions, solvents, media, and the like.

专利号:US-2020062687-A1
优先权日:2016-12-22
标 题:Fragrance and flavor materials
发明人:BLANDINO MAUREEN; LANKIN MICHAEL E
权利人:TAKASAGO PERFUMERY CO LTD
摘要:The present disclosure is directed to the synthesis and application of ethyl linalool derivatives having unique and desired flavor and/or fragrance characteristics. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The present disclosure is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions.
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合成参考文献


摘要:Gagnon, A.; Benoit, E.; Le Roch, A., Science of Synthesis Knowledge Updates, (2018) 4, 69.
摘要:Bonrath, W.; Medlock, J. A.; Müller, M.-A., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 214.
摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
摘要:Joosten, A.; Brioche, J., Science of Synthesis: Modern Strategies in Organofluorine Chemistry , (2024) 1, 22.
摘要:Amii, H., Science of Synthesis: Modern Strategies in Organofluorine Chemistry, (2025) 2.
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