CAS: 32692-19-6; 5-Nitroindoline

上下游产品

5-硝基-1,3-二氢-2H-吲哚-2-酮 5-Nitrooxindole 20870-79-5
1-乙酰基-5-硝基二氢吲哚 1-(5-Nitro-2,3-Dihydroindol-1-yl)Ethanone 33632-27-8
吲哚啉 1-Indoline 496-15-1
(5-Nitroindolin-1-yl)(Phenyl)Methanone 108619-08-5

5-硝基-1,3-二氢-2H-吲哚-2-酮置于硼烷四氢呋喃络合物体系中,用 四氢呋喃 作为反应溶剂,化学反应 0.5H,以54%的收率获得产物5-硝基二氢吲哚
参考文献:Quinolone And Tetrahydroquinolone And Related Compounds Having Nos Inhibitory Activity
标题:Quinolone And Tetrahydroquinolone And Related Compounds Having Nos Inhibitory Activity
摘要:本发明涉及抑制一氧化氮合酶(nos)的喹诺酮,四氢喹啉和相关化合物,特别是那些选择性地抑制神经型一氧化氮合酶(nnos)而不是其他nos同工型的化合物.本发明的nos抑制剂,单独或与其他药用活性剂结合使用,可用于治疗或预防各种医疗状况.

专利信息

专利号:US-9969685-B2
优先权日:2016-09-28
标 题 :Enantioselective synthesis of pyrroloindole compounds
发明人：SCHMIDT MICHAEL ANTHONY
权利人:BRISTOL MYERS SQUIBB CO
摘要:Compounds according to formula (I) or (II), wherein R 1 , R 2 , and R 3 are as defined in the specification, are versatile intermediates for the synthesis of DNA minor groove binder-alkylators having a cyclopropapyrroloindole (CPI) or seco-CPI alkylating subunit.

专利号:CN-108997189-A
优先权日:2017-06-07
标题:Catalyst for one-step synthesis of indole and preparation method thereof

专利号:US-2018086701-A1
优先权日:2016-09-28
标 题:Enantioselective synthesis of pyrroloindole compounds

专利号:CN-105523986-A
优先权日:2015-12-30
标 题 :A kind of synthesis method of efflux pump inhibitor N-hydrogen-2-arylindole and its derivatives

专利号:CN-106103716-A
优先权日:2013-07-12
标题:Method for RNA Interfering with DNA Polymerase and Inhibiting DNA Synthesis and Components of Its Complex

专利号:CN-103435528-A
优先权日:2013-07-17
标题:A simple synthesis process of an important pharmaceutical and chemical intermediate 5-nitroindole