CAS: 38180-46-0; 3-Chloro-2-Cyanopyridine

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2,3-二氯吡啶 以 二氯甲烷,N,N-二甲基甲酰胺 用作溶剂,以1.05 G (76%)的收率获得3-氯-2-氰基吡啶
参考文献:Heteropolycyclic Compounds And Their Use As Metabotropic Glutamate Receptor Antagonists
标题:Heteropolycyclic Compounds And Their Use As Metabotropic Glutamate Receptor Antagonists
摘要:本发明提供了作为代谢型谷氨酸受体拮抗剂的化合物和药物组合物,用于治疗神经系统疾病和障碍.还公开了制备这些化合物的方法.

专利信息

专利号:US-5204478-A
优先权日:1992-08-20
标题 :Process for the synthesis of 2,6-dichloro-5-fluoronicotinic acid and 2,6-dichloro-5-fluoronicotinoyl chloride
发明人：JENNINGS REX A
权利人:WARNER LAMBERT CO
摘要:An improved process for the preparation of 2,6-dichloro-5-fluoronicotinoyl chloride is described where a 2,6-dihydroxy-5-fluoronicotinic acid ester is converted in one step using phosphorus oxychloride and a lithium reagent to 2,6-dichloro-5-fluoronicotinoyl chloride and subsequent basic hydrolysis affords 2,6-dichloro-5-fluoronicotinic acid.

专利号:WO-2015123228-A1
优先权日:2014-02-11
标题 :Processes for the synthesis of intermediates of the herbicide flucetosulfuron
发明人：SHOU WANGGE; CHEN JIANGUO
权利人:FMC CORP
摘要:Processes for preparing intermediates of flucetosulfuron, a sulfonyl urea herbicide, are disclosed. Intermediate compounds are also presented.

专利号:US-12269802-B2
优先权日:2018-05-09
标题:Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl] amino] acetic acid
发明人：GORIN BORIS I; LANTHIER CHRISTOPHER M; LUONG ANNE BUU CHAU; COPP JAMES DENSMORE; GONZALEZ JAVIER; JAUTZE SASCHA; KRAUS ERICH; O'CONNOR ALAN
权利人:AKEBIA THERAPEUTICS INC
摘要:Disclosed herein are methods and processes of preparing vadadustat and pharmaceutically acceptable salts thereof, and intermediates of formula (I) and their salts useful for the synthesis of vadadustat.

专利号:EP-0655998-B1
优先权日:1992-08-20
标题:Improved process for the synthesis of 2,6-dichloro-5-fluoronicotinic acid and 2,6-dichloro-5-fluoronicotinoyl chloride

专利号:EP-0655998-A1
优先权日:1992-08-20
标 题 :METHOD FOR THE SYNTHESIS OF 2,6-DICHLOR-5-FLUORNICOTINIC ACID AND 2,6-DICHLOR-5-FLUORNICOTINOYL CHLORIDE.

专利号:WO-9404501-A1
优先权日:1992-08-20
标题 :Improved process for the synthesis of 2,6-dichloro-5-fluoronicotinic acid and 2,6-dichloro-5-fluoronicotinoyl chloride