2-氯丙酸置于phosphonic Acid,氯体系中,化学反应生成 2,2-二氯丙酸 参考文献:Process For Making Alpha,Alphadihalopropionic Acids 标题:Process For Making Alpha,Alphadihalopropionic Acids
专利号:US-7304191-B2 优先权日:2000-08-07 标 题:Process for the synthesis of fluoroorganic compounds 发明人:MATHIEU VERONIQUE; JANSSENS FRANCINE; FRANKLIN JAMES 权利人:SOLVAY 摘要:The present invention relates to a fluorination method for the synthesis of halofluoroorganic compounds which can be used, inter alia, as precursors in the synthesis of 2,3-unsaturated fluoroorganic carbonyl compounds comprising a fluorine substituent in the 2 position.
专利号:US-7084281-B2 优先权日:2003-01-22 标题:Synthesis of dihalohydrins and tri- and tetra-substituted olefins 发明人:FALCK JOHN R; BARMA DEB K; KUNDU ABHIJIT 权利人:UNIV TEXAS 摘要:A novel synthesis reaction for highly stereospecific tri- and tetra-substituted olefins is described. A single stereoisomer of stable α-halo-α,β-ester is produced in high yield by the reaction of aldehyde or ketone with a trihalogenated compound such as trichloroacetate in the presence of CrCl 2 in a solvent. By varying the amount of CrCl 2 used, the stable dihalohydrin intermediate may be obtained as well.
专利号:WO-2024256370-A1 优先权日:2023-06-13 标 题 :Synthesis of glufosinate using an amidase-based process 发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN 权利人:BASF SE 摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.
专利号:US-2025120400-A1 优先权日:2021-12-10 标题:Synthesis of glufosinate using a hydantoinase-based process 发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN 权利人:BASF SE 摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.
专利号:WO-03064371-A1 优先权日:2002-02-01 标题 :Synthesis of fluorinating agents 发明人:CLEMENT MANDY 权利人:F2 CHEMICALS LTD; CLEMENT MANDY 摘要:The invention provides a method for the preparation of an acyl hypofluorite (I), the method comprising treating a mixture comprising a lower nitrile and a carboxylic acid with elemental fluorine. The preferred acyl hypofluorite is acetyl hypofluorite, the corresponding carboxylic acid is acetic acid, and the preferred nitrile is acetonitrile. The reaction is preferably carried out in a single phase on a continuous basis at room temperature, by treating a mixture of nitrile and carboxylic acid with a stream containing 10% fluorine gas in an inert gas such as nitrogen.
专利号:US-11919928-B2 优先权日:2016-03-16 标题 :Method for producing dihydrotentoxin 发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI 权利人:KUMIAI CHEMICAL INDUSTRY CO 摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.
参考标题:Palladium-Catalyzed Synthesis Of Benzofurans Via C-H Activation/oxidation Tandem Reaction And Its Application To The Synthesis Of Decursivine And Serotobenine 作者:Lei Guo,Fengying Zhang,Weimin Hu,Lei Li,Yanxing Jia 摘要:A New Palladium-Catalyzed Method For The Synthesis Of Benzofurans By Reaction Of 2-Hydroxystyrenes And Iodobenzenes Via A Câh Activation/oxidation Tandem Reaction Has Been Unprecedentedly Discovered. By Using This Strategy, The Overall Synthetic Efficiency Of The Synthesis Of Decursivine And Its Analogues Was Indeed Improved. Preliminary Mechanistic Studies Shed Light Into The Possible Mechanisms.
合成参考文献
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