CAS: 760-21-4; 2-Ethyl-1-Butene

该化合物是一种有机化合物,由于结构中存在碳碳的双重结合,因此被归类为烷,由五碳链组成,在第三和第四个碳原子之间有双重结合,其特征为不饱和,与饱和碳氢化合物相比,它有助于其再活性.3-甲基戊烷在室温下一般是一种无色液体,表现出一种独特的碳氢气味.其分子式为C5H8,表明它有8个氢原子,用于5个碳原子,反映了其不饱和的性质.该化合物在有机溶剂中溶解,但在水中溶解度有限.由于存在双重结合,它可以发生各种化学反应,包括增加反应,使其在有机合成中有用.在处理这一化合物时,应当采取安全防范措施,因为如果吸入或浸泡,它可能是易燃的,而且可能有害.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号97-95-0 2-乙基-1-丁醇 | CAS号616-12-6 反-3-甲基-2-戊烯 | CAS号54509-73-8 ethene | CAS号592-41-6 1-己烯 | CAS号625-27-4 2-甲基-2戊烯 | CAS号6974-30-7 Butane,1-bromo-... | CAS号2065-66-9 甲基三苯基碘化 | CAS号96-22-0 3-戊酮 | CAS号4737-41-1 3-(氯甲基)戊烷 | CAS号859776-79-7 3-ethoxy-3-brom... | CAS号19792-52-0 2-氨基-2-丁基己醇 | CAS号77-74-7 3-甲基-3-戊醇 | CAS号96-14-0 3-甲基苯酚甲酯 | CAS号625-27-4 2-甲基-2戊烯 | CAS号616-12-6 反-3-甲基-2-戊烯 | CAS号13921-07-8 2-ethylbutylsul... | CAS号88-09-5 2-乙基丁酸 | CAS号1192-17-2 Oxirane, 2,2-diethyl | CAS号66225-51-2 3-Ethyl-1-pentanol | CAS号66553-16-0 2-ethylbutane-1...

合成工艺路线路线简述

    2-甲基-2-戊烯置于thorium Dioxide体系中,化学反应生成 2-乙基-1-丁烯
    参考文献:Goldwasser; Taylor,Journal Of The American Chemical Society,1939,Vol. 61,P. 1757
    标题:Goldwasser; Taylor,Journal Of The American Chemical Society,1939,Vol. 61,P. 1757

    海关参考信息

    专利信息


    专利号:US-8084007-B2
    优先权日:2004-01-30
    标题 :Methods of synthesis of isotropically enriched borohydride and methods of synthesis of isotropically enriched boranes
    发明人:SPIELVOGEL BERNARD; COOK KEVIN S
    权利人:SPIELVOGEL BERNARD; COOK KEVIN S; SEMEQUIP INC
    摘要:The invention provides new methods for the synthesis of isotopically enriched metal borohydrides, metal tetrahydroundecaborate salts, and decaborane from isotopically enriched 10 B-boric acid or 11 B-boric acid. The invention is particularly useful for synthesis of isotopically enriched sodium or lithium borohydride, MB 11 H 14 (where M is Li, Na, K, or alkylammonium), and decaborane.

    专利号:US-7825244-B2
    优先权日:2005-06-10
    标题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
    发明人:BAINDUR NAND; GAUL MICHAEL DAVID; KREUTTER KEVIN DOUGLAS; XU GUOZHANG
    权利人:JANSSEN PHARMACEUTICA NV
    摘要:The invention is directed to alkylquinoline and alkylquinazoline compounds of Formula C: n nwherein R 1 , R 2 , R 99 , and X are as defined herein, the use of such compounds in the synthesis of protein tyrosine kinase inhibitors, particularly inhibitors of FLT3 and/or c-kit and/or TrkB.

    专利号:US-2023183177-A1
    优先权日:2020-04-24
    标题:Enantioselective chemo-enzymatic synthesis of optically active amino amide compounds
    发明人:GRILL BIRGIT; WINKLER MARGIT; SCHWAB HELMUT; STROHMEIER GERNOT; DONSBACH KAI; WALDVOGEL SIEGFRIED R; ARNDT SEBASTIAN; WEIS DOMINIK
    权利人:PHARMAZELL GMBH
    摘要:The present invention relates to a novel biocatalytic process for the stereoselective preparation of alpha amino amide compounds catalyzed by NHase enzymes. A further aspect of the invention relates to novel NHase enzymes as well as further improved NHase enzyme mutants, nucleic acid molecules encoding these enzymes, recombinant microorganisms suitable for preparing such enzymes and mutants. Another aspect of the invention relates to a chemo-biocatalytic process for the preparation of lactam compounds comprising the new catalytic process for the preparation of alpha amino amide compounds catalyzed by NHase enzymes, as well as the chemical oxidation of the alpha amino amide by applying certain chemical oxidation catalysts suitable for converting the alpha amino amide under retention of its stereochemical configuration to the respective lactam. The novel chemo-biocatalytic process is particularly suited for the synthesis of valuable pharmaceutical compounds, like in particular (S)-Levetiracetam.

    专利号:US-10570114-B2
    优先权日:2016-05-19
    标题:Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling
    发明人:FISK JASON S; LI XIAOYONG; Muehlfeld Mark; BAUMAN ROBERT S; OPPENHEIMER JOSSIAN; TU SIYU; NITZ MARK A; CHAKRABARTI REETAM; FEIST SHAWN D; RINGER JAMES W; LENG RONALD B
    权利人:DOW AGROSCIENCES LLC
    摘要:Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.

    专利号:US-2013184465-A1
    优先权日:2010-09-30
    标 题:Process for the synthesis of thio-triazolo-group containing compounds
    发明人:DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL
    权利人:DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL; BASF SE
    摘要:The present invention relates to a process using specific magnesium reagents for providing thio-triazolo group-containing compounds and for the synthesis of precursors therefor. The invention furthermore relates to intermediates and to their preparation.

    专利号:US-9403854-B2
    优先权日:2001-03-30
    标 题 :Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts
    发明人:GRUBBS ROBERT H; CHATTERJEE ARNAB K; CHOI TAE-LIM; GOLDBERG STEVEN D; LOVE JENNIFER A; MORGAN JOHN P; SANDERS DANIEL P; SCHOLL MATTHIAS; TOSTE F DEAN; TRNKA TINA M
    权利人:CALIFORNIA INST OF TECHN
    摘要:The invention pertains to the use of Group 8 transition metal carbene complexes as catalysts for olefin cross-metathesis reactions. In particular, ruthenium and osmium alkylidene complexes substituted with an N-heterocyclic carbene ligand are used to catalyze cross-metathesis reactions to provide a variety of substituted and functionalized olefins, including phosphonate-substituted olefins, directly halogenated olefins, 1,1,2-trisubstituted olefins, and quaternary allylic olefins. The invention further provides a method for creating functional diversity using the aforementioned complexes to catalyze cross-metathesis reactions of a first olefinic reactant, which may or may not be substituted with a functional group, with each of a plurality of different olefinic reactants, which may or may not be substituted with functional groups, to give a plurality of structurally distinct olefinic products. The methodology of the invention is also useful in facilitating the stereoselective synthesis of 1,2-disubstituted olefins in the cis configuration.
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    合成参考文献


    摘要:Kostikov, R. R.; Khlebnikov, A. F.; Sokolov, V. V., Science of Synthesis, (2010) 47, 780.
    摘要:de Meijere, A.; Kozhushkov, S. I., Science of Synthesis, (2009) 48, 540.
    摘要:Kostikov, R. R.; Khlebnikov, A. F.; Sokolov, V. V., Science of Synthesis, (2010) 47, 821.
    摘要:Kostikov, R. R.; Khlebnikov, A. F.; Sokolov, V. V., Science of Synthesis, (2010) 47, 803.
    摘要:Dembitsky, V. M.; Yaremenko, I. A., Science of Synthesis Knowledge Updates, (2020) 2, 298.
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